Complex formation reactions of palladium(II)-1,3-diaminopropane with various biologically relevant ligands. Kinetics of hydrolysis of glycine methyl ester through complex formation

• Authors: Ahmed El-Sherif , Mohamed Shoukry , Ramadan El-Bahnasawy , Dalia Ahmed
• Languages of publication: EN

Abstracts

EN

The interaction of [Pd(DAP)(H2O)2]2+ (DAP = 1,3-diaminopropane) with some selected bio-relevant ligands, containing different functional groups, were investigated. The ligands used are dicarboxylic acids, amino acids, peptides and DNA constituents. Stoichiometry and stability constants of the complexes formed are reported at 25°C and 0.1 M ionic strength. The results show the formation of 1:1 complexes with amino acids and dicarboxylic acids. The effect of chelate ring size of the dicarboxylic acid complexes on their stability constants is examined. Peptides form both 1:1 complexes and the corresponding deprotonated amide species. DNA constituents form 1:1 and 1:2 complexes. The effect of dioxane on the acid dissociation constants of CBDCA and the formation constant of its complex with Pd(DAP)2+ was reported. The kinetics of hydrolysis of glycine methyl ester bound to [Pd(DAP)(H2O)2]2+ was studied at 25°C and 0.1M ionic strength. [...]

Keywords

EN

Amino acids; 1,3-diaminopropane; Peptides; DNA constituents and potentiometric titration

• Publisher: De Gruyter Open
• Journal: Open Chemistry
• Year: 2010
• Volume: 8
• Issue: 4
• Pages: 919-927

Dates

published

1 - 8 - 2010

online

17 - 6 - 2010

Contributors

author

Ahmed El-Sherif

• Faculty of Science, Chemistry Department, Cairo University, P.O. Box 12611, Cairo, Egypt

author

Mohamed Shoukry

• Faculty of Science, Chemistry Department, Cairo University, P.O. Box 12611, Cairo, Egypt

author

Ramadan El-Bahnasawy

• Faculty of Science, Chemistry Department, Elmenoufia University, Shebeen El-Koom, P.O. Box, 13040, Egypt

author

Dalia Ahmed

• Faculty of Science, Chemistry Department, Elmenoufia University, Shebeen El-Koom, P.O. Box, 13040, Egypt

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Identifiers

DOI

10.2478/s11532-010-0057-4