Efficient Lewis acid-assisted Brønsted acid (LBA) catalysis in the iron-catalyzed Friedel-Crafts alkylation reaction of indoles

• Authors: Zhen-Yu Jiang , Ji-Rong Wu , Li Li , Xi-Huai Chen , Guo-Qiao Lai , Jian-Xiong Jiang , Yixin Lu , Li-Wen Xu
• Languages of publication: EN

Abstracts

EN

Lewis acid-assisted Brønsted acid (LBA) catalysis was proposed for the iron-catalyzed Friedel-Crafts alkylation of indoles with chalcones. This proposal was supported by the ESI-MS and cyclic voltammetry. The addition of acac to the iron-catalyzed Friedel-Crafts alkylation of indoles with chalcones created a powerful catalytic system, which makes the alkylation reactions occur easily under mild conditions. [...]

Keywords

EN

Iron catalysis; Friedel-Crafts; Lewis acid; Brønsted acid

• Publisher: De Gruyter Open
• Journal: Open Chemistry
• Year: 2010
• Volume: 8
• Issue: 3
• Pages: 669-673

Dates

published

1 - 6 - 2010

online

25 - 4 - 2010

Contributors

author

Zhen-Yu Jiang

• Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education, Hangzhou Normal University, Hangzhou, 310012, P. R. China

author

Ji-Rong Wu

• Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education, Hangzhou Normal University, Hangzhou, 310012, P. R. China

author

Li Li

author

Xi-Huai Chen

• Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education, Hangzhou Normal University, Hangzhou, 310012, P. R. China

author

Guo-Qiao Lai

• Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education, Hangzhou Normal University, Hangzhou, 310012, P. R. China

author

Jian-Xiong Jiang

• Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education, Hangzhou Normal University, Hangzhou, 310012, P. R. China

author

Yixin Lu

• Department of Chemistry, National University of Singapore, Singapore, 117543, Republic of Singapore

author

Li-Wen Xu

• Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education, Hangzhou Normal University, Hangzhou, 310012, P. R. China

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Identifiers

DOI

10.2478/s11532-010-0016-0