Hydrate of 2,3:4,5-di-O-isopropylidene-β-D-arabino-hexos-2-ulo-2,6-pyranose as new crystalline reagent in the preparation of Amadori derived peptides

• Authors: Piotr Stefanowicz , Joanna Batorska , Monika Kijewska , Hubert Bartosz-Bechowski , Zbigniew Szewczuk , Tadeusz Lis
• Languages of publication: EN

Abstracts

EN

We established, that crystalline hydrate of 2,3:4,5-di-O-isopropylidene-β-D-arabino-hexos-2-ulo-2,6-pyranose is a new, convenient and stable reagent for solid phase synthesis of peptide derived Amadori products. The structure of the title compound was studied by X-ray analysis, NMR spectroscopy, and high resolution ESI-MS. The crystal structure indicated the existence of two symmetry-independent molecules that were not connected with hydrogen bonds. A comparison with previously reported 2,3:4,5-di-O-isopropylidene-β-D-fructopyranose revealed, that these two compounds are isostructural. [...]

Keywords

EN

2,3:4,5-di-O-isopropylidene-β-D-arabino-hexos-2-ulo-2,6-pyranose; solid phase synthesis; X-ray studies; Amadori products

• Publisher: De Gruyter Open
• Journal: Open Chemistry
• Year: 2010
• Volume: 8
• Issue: 1
• Pages: 28-33

Dates

published

1 - 2 - 2010

online

16 - 2 - 2010

Contributors

author

Piotr Stefanowicz

• Faculty of Chemistry, University of Wrocław, 50-383, Wrocław, Poland

author

Joanna Batorska

• Faculty of Chemistry, University of Wrocław, 50-383, Wrocław, Poland

author

Monika Kijewska

• Faculty of Chemistry, University of Wrocław, 50-383, Wrocław, Poland

author

Hubert Bartosz-Bechowski

• Faculty of Chemistry, University of Wrocław, 50-383, Wrocław, Poland

author

Zbigniew Szewczuk

• Faculty of Chemistry, University of Wrocław, 50-383, Wrocław, Poland

author

Tadeusz Lis

• Faculty of Chemistry, University of Wrocław, 50-383, Wrocław, Poland

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Identifiers

DOI

10.2478/s11532-009-0123-y