Poly(methylhydrosiloxane)-supported chiral thiourea-based bifunctional catalysts

• Authors: Alessandra Puglisi , Maurizio Benaglia , Elisabetta Massolo , Giuseppe Celentano
• Languages of publication: EN

Abstracts

EN

The design, the synthesis and the successful immobilization of a modified Takemoto's catalyst is described. As support, poly(methylhydrosiloxane (PMHS) was chosen for its several positive features: it is a cheap, commercially available polymer, easily functionalized with simple experimental procedures. The PMHS-anchored enantiomerically pure bifunctional organocatalyst was employed in the stereoselective addition of activated carbon nucleophiles to nitrostyrene and its recovery and recyclability was preliminarily investigated.

Keywords

EN

Organocatalysis; Supported catalysts; Poly(methylhydrosiloxane); Chiral thioureas; Michael addition

• Publisher: De Gruyter Open
• Journal: Recyclable Catalysis
• Year: 2012
• Volume: 1
• Pages: 1-5

Dates

online

23 - 8 - 2012

Contributors

author

Alessandra Puglisi

• Dipartimento di Chimica, Università degli Studi di Milano, via Golgi 19, 20133, Milano, Italy

author

Maurizio Benaglia

• Dipartimento di Chimica, Università degli Studi di Milano, via Golgi 19, 20133, Milano, Italy

author

Elisabetta Massolo

• Dipartimento di Chimica, Università degli Studi di Milano, via Golgi 19, 20133, Milano, Italy

author

Giuseppe Celentano

• Dipartimento di Scienze Farmaceutiche, Università degli Studi di Milano, Via Mangiagalli 25, 20133, Milano, Italy

References

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• S. Guizzetti, M. Benaglia, J. S. Siegel, Chem. Comm. 2012, 3188-3190.
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• Typically supported catalyst 9 with a 1:1 x/y ratio was employed in catalytic experiments; the use of polymers with different x/y ratio did not bring any appreciable variation in the stereochemical efficiency of the catalytic system.

Identifiers

DOI

10.2478/recat-2012-0001