The Formation of Polycomplexes of Poly(Methyl Vinyl Ether-Co-Maleic Anhydride) and Bovine Serum Albumin in the Presence of Copper Ions

• Authors: Mesut Karahan , Zeynep Mustafaeva , Cemal Özeroğlu
• Languages of publication: EN

Abstracts

EN

The binary and ternary complex formations of poly(methyl vinyl ether-co-maleic anhydride) (PMVEMA) with copper ions and with bovine serum albumin (BSA) in the presence of copper ions in phosphate buffer solution at pH = 7 were examined by the techniques of UV-visible, fluorescence, dynamic light scattering, atomic force microscopy measurements. In the formation of binary complexes of PMVEMA-Cu(II), the addition of copper ions to the solution of PMVEMA in phosphate buffer solution at pH = 7 forms homogeneous solutions when the molar ratio of Cu(II)/MVEMA is 0.5. Then the formations of ternary complexes of PMVEMA-Cu(II)-BSA were examined. Study analysis revealed that the toxicities of polymer-metal and polymer-metal-protein mixture solutions depend on the nature and ratio of components in mixtures.

Keywords

EN

polyelectrolyte; bovine serum albumin; copper ions; metal complexes; biological processes; biomaterials

• Publisher: De Gruyter Open
• Journal: Polish Journal of Chemical Technology
• Year: 2014
• Volume: 16
• Issue: 3
• Pages: 97-105

Dates

published

1 - 9 - 2014

online

3 - 10 - 2014

Contributors

author

Mesut Karahan

• Üsküdar University, Faculty of Engineering and Natural Sciences, Department of Bioengineering, 34662 Uskudar-Istanbul, Turkey

author

Zeynep Mustafaeva

• Yildiz Technical University, Faculty of Chemical and Metallurgical Engineering, Department of Bioengineering, 34220 Esenler-Istanbul Turkey

author

Cemal Özeroğlu

• Istanbul University, Faculty of Engineering, Department of Chemistry, 34320 Avcılar-Istanbul Turkey

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Identifiers

DOI

10.2478/pjct-2014-0058