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Number of results
2014 | 1 | 1 |

Article title

Imaging of myocardial infarction with
thermoacoustic tomography: An ex vivo study

Content

Title variants

Languages of publication

EN

Abstracts

EN
In the present study, we evaluated the feasibility
of thermoacoustic tomography (TAT) for imaging of ex
vivo mouse hearts with myocardial infarction. A circular
scanning TAT system with an unfocused transducer was
used to recover the dielectric property distribution of normal
andmyocardial infarcted mouse heart tissues. The applicability
of this myocardial infarction imaging system
was validated using a model of myocardial infarction in
two Sprague-Dawley rats and verified through comparison
with magnetic resonance imaging (MRI). TAT results not
only indicated the location and ischemia and the extent of
myocardial ischemia (MI), but also showed good imaging
contrast between infarcted and normal myocardium without
the use of contrast agent. The experimental results suggest
that TAT may provide a unique opportunity to enable
real-time precision imaging to determine the site of injury
intraoperatively

Publisher

Year

Volume

1

Issue

1

Physical description

Dates

received
1 - 12 - 2014
accepted
18 - 5 - 2015
online
18 - 8 - 2015

Contributors

author
  • School of Physical Electronics,
    University of Electronic Science and Technology of China,
    Chengdu, 610054, China
author
  • Department
    of radiology, Beijing Jishuitan hospital, Beijing, 100035, China
author
  • The Fourth Affiliated Hospital of China Medical University,
    Shenyang, 110032, China
author
  • School of Physical Electronics,
    University of Electronic Science and Technology of China,
    Chengdu, 610054, China
author
  • School of Physical Electronics,
    University of Electronic Science and Technology of China,
    Chengdu, 610054, China

References

  • [1] Lou, C., & Xing, D. (2010). Temperature monitoring utilisingthermoacoustic signals during pulsed microwave thermotherapy:a feasibility study. International Journal of Hyperthermia,26(4), 338-346.[Crossref][WoS]
  • [2] Nie, L., Xing, D., Zhou, Q., Yang, D., & Guo, H. (2008).Microwave-induced thermoacoustic scanning CT for highcontrastand noninvasive breast cancer imaging. Medicalphysics, 35(9), 4026-4032.[WoS][Crossref]
  • [3] Zhu, L., Xu, L. X., & Chencinski, N. (1998). Quantification ofthe 3-D electromagnetic power absorption rate in tissue duringtransurethral prostatic microwave thermotherapy usingheat transfer model. Biomedical Engineering, IEEE Transactionson, 45(9), 1163-1172.
  • [4] Pham, T., Beigie, C., Park, Y., & Wong, J. Y. (2014). Microbubblesas Theranostics Agents. In Nano-Oncologicals (pp. 329-350).Springer International Publishing.
  • [5] Ogunlade, O., & Beard, P. (2014, March). Electric and magneticproperties of contrast agents for thermoacoustic imaging. InSPIE BiOS (pp. 89432V-89432V). International Society for Opticsand Photonics.
  • [6] Osepchuk, J. M., & Petersen, R. C. (2001). Safety standards forexposure to RF electromagnetic fields. Microwave Magazine,IEEE, 2(2), 57-69.
  • [7] Huang, L., Yao, L., Liu, L., Rong, J., & Jiang, H. (2012). Quantitativethermoacoustic tomography: Recovery of conductivitymaps of heterogeneous media. Applied Physics Letters,101(24), 244106.[WoS][Crossref]
  • [8] Huang, L., Liu, L., Lu, K., Zhong, X., Li, T., Chen, B., & Jiang, H. 3GHz Thermoacoustic Tomography System.
  • [9] Nikolova, N. K. Microwave Biomedical Imaging. Wiley Encyclopediaof Electrical and Electronics Engineering.
  • [10] Janse, M. J., & Wit, A. L. (1989). Electrophysiological mechanismsof ventricular arrhythmias resulting from myocardial ischemiaand infarction. Physiol Rev, 69(4), 1049-1169.
  • [11] Serguei Y. S., Alexander E. B., Vitaly G. P., Yuri E. S., Thomas C.W., Alexander E. S. (2003). Microwave Tomography for Detection/Imaging ofMyocardial Infarction. I. Excised Canine Hearts.Annals of Biomedical Engineering, 31(3), 262-270.[Crossref]
  • [12] Rajiah P., Desai M. Y., Kwon D., Flamm S. D. (2013). MR imagingof myocardial infarction. Sep-Oct, 33(5), 1383-412.

Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.-psjd-doi-10_1515_phto-2015-0003
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