Preliminary Clinical Study On Ms Treatment With Hyperbaric Oxygenation

• Authors: Kazimierz Ulewicz , Janusz Masłowski , Przemysław Michniewski , Brunon Kierznikowicz , Romuald Olszański
• Languages of publication: EN

Abstracts

EN

The authors conducted the preliminary clinical investigation on 16 multiple sclerosis (Sclerosis multiplex) patients of median disease duration 9.33 years and symptoms evaluated on Kurtzke’s scale. The patients underwent between 25 and 30 hyperbaric oxygen exposures at a pressure of 2 ata in intervals spread over a few days. The patients were qualified and classified to the treatment symptomatologically according to Fisher but the obtained results were evaluated according to the standardised Disability Status Scale by Kurtzke. During the investigations the authors carried out additional quantitative immunoglobulin and complement activity determination, lymphocyte T and B determinations as well as the usually applied clinical and laboratory investigations. Evident clinical improvement was observed in 14 patients, but in the case of one patient a deterioration was observed after 15 hyperbaric expositions (resulting in the hyperbaric oxygen treatment being stopped), whilst in another case no curative effect could be observed. By utilising the 50% haemolysis method, within the examined immunological parameters the authors observed an increase of complement fractions and its activity, white lymphocytes T and B examined qualitatively did not maintain the characteristic shift. The authors are still discussing the obtained results.

Keywords

EN

hyperbaric oxygen; sclerosis multiplex; therapy

• Publisher: De Gruyter Open
• Journal: Polish Hyperbaric Research
• Year: 2015
• Volume: 51
• Issue: 2
• Pages: 47-51

Dates

published

1 - 6 - 2015

online

18 - 11 - 2015

accepted

2 - 6 - 2014

Contributors

author

Kazimierz Ulewicz

• Department of Human Epidemiology and Ecology of the Institute of Clinical Medicine, Medical Academy of Cracow in Rzeszów, Maritime and Tropical Medicine Institute of Gdynia, Maritime Medicine Institute of the Warsaw Medical Academy in Gdynia, Poland

author

Janusz Masłowski

• Department of Human Epidemiology and Ecology of the Institute of Clinical Medicine, Medical Academy of Cracow in Rzeszów, Maritime and Tropical Medicine Institute of Gdynia, Maritime Medicine Institute of the Warsaw Medical Academy in Gdynia, Poland

author

Przemysław Michniewski

• Department of Human Epidemiology and Ecology of the Institute of Clinical Medicine, Medical Academy of Cracow in Rzeszów, Maritime and Tropical Medicine Institute of Gdynia, Maritime Medicine Institute of the Warsaw Medical Academy in Gdynia, Poland

author

Brunon Kierznikowicz

• Department of Human Epidemiology and Ecology of the Institute of Clinical Medicine, Medical Academy of Cracow in Rzeszów, Maritime and Tropical Medicine Institute of Gdynia, Maritime Medicine Institute of the Warsaw Medical Academy in Gdynia, Poland

author

Romuald Olszański

• Department of Human Epidemiology and Ecology of the Institute of Clinical Medicine, Medical Academy of Cracow in Rzeszów, Maritime and Tropical Medicine Institute of Gdynia, Maritime Medicine Institute of the Warsaw Medical Academy in Gdynia, Poland

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Identifiers

DOI

10.1515/phr-2015-0010