BANSAI - An optofluidic approach for biomedical
analysis

• Authors: Markus Knoerzer , Christoph Prokop , Graciete M. Rodrigues Ribeiro , Horst Mayer , Jens Brümmer , Arnan Mitchell , Dominik G. Rabus , Christian Karnutsch
• Languages of publication: EN

Abstracts

EN

Lab-on-a-chip based portable blood analysis
systems would allow point-of-care measurements, e.g. in
an ambulance, or in remote areas with no fast access to
medical care. Such a systemwould provide much faster information
about the health of a patient. Here,we present a
system that is based on absorption spectroscopy and uses
an organic laser, which is tunable in the visible range. The
feasibility of the system is shown with a table-top setup
using laboratory equipment. Measurements of human albumin
show linear behaviour in a range from 2.5 g/L to
60 g/L. In a consecutive setup the system is implemented
on a microfluidic chip and is capable of measuring
simultaneously transmitted and side scattered intensities,
even with ambient light present. Air-suspended grating
couplers on polymers are shown as the first element of a
lab-on-a-chip implementation.

Keywords

EN

optofluidic; microfluidic; biomedical analysis; blood analysis; lab-on-a-chip; point-of-care analysis; organiclaser

• Publisher: De Gruyter Open
• Journal: Optofluidics, Microfluidics and Nanofluidics
• Year: 2015
• Volume: 2
• Issue: 1

Dates

received

12 - 9 - 2015

online

31 - 12 - 2015

accepted

8 - 11 - 2015

Contributors

author

Markus Knoerzer

• Institute for Optofluidics and
  Nanophotonics (IONAS), Karlsruhe University of Applied Sciences,
  Moltkestr. 30, 76133 Karlsruhe, Germany
• Microplatforms Research Group, School of Electrical and
  Computer Engineering, RMIT University, GPO Box 2476, Melbourne
  VIC 3001, Australia

author

Christoph Prokop

• Institute for Optofluidics and
  Nanophotonics (IONAS), Karlsruhe University of Applied Sciences,
  Moltkestr. 30, 76133 Karlsruhe, Germany
• Microplatforms Research Group, School of Electrical and
  Computer Engineering, RMIT University, GPO Box 2476, Melbourne
  VIC 3001, Australia

author

Graciete M. Rodrigues Ribeiro

• Zentralinstitut
  für Laboratoriumsmedizin, Mikrobiologie und Transfusionsmedizin,
  Städtisches Klinikum Karlsruhe, Moltkestr. 90, 76133
  Karlsruhe, Germany

author

Horst Mayer

• Zentralinstitut
  für Laboratoriumsmedizin, Mikrobiologie und Transfusionsmedizin,
  Städtisches Klinikum Karlsruhe, Moltkestr. 90, 76133
  Karlsruhe, Germany

author

Jens Brümmer

• Zentralinstitut
  für Laboratoriumsmedizin, Mikrobiologie und Transfusionsmedizin,
  Städtisches Klinikum Karlsruhe, Moltkestr. 90, 76133
  Karlsruhe, Germany

author

Arnan Mitchell

• Microplatforms Research Group, School of Electrical and
  Computer Engineering, RMIT University, GPO Box 2476, Melbourne
  VIC 3001, Australia

author

Dominik G. Rabus

• Microplatforms Research Group, School of Electrical and
  Computer Engineering, RMIT University, GPO Box 2476, Melbourne
  VIC 3001, Australia
• Bürkert Fluid Control Systems, Christian-Bürkert-
  Str. 13-17, 74653 Ingelfingen, Germany

author

Christian Karnutsch

• Institute for Optofluidics and
  Nanophotonics (IONAS), Karlsruhe University of Applied Sciences,
  Moltkestr. 30, 76133 Karlsruhe, Germany

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Identifiers

DOI

10.1515/optof-2015-0003