The dynamics of the surface layer of lipid membranes doped by vanadium complex: computer modeling and EPR studies

• Authors: Ryszard Olchawa , Dariusz Man , Barbara Pytel
• Languages of publication: EN

Abstracts

EN

Penetration of the liposome membranes doped with vanadium complex formed in the liquid-crystalline phase from egg yolk lecithin (EYL) by the TEMPO (2,2,6,6-tetramethylpiperidine-1-oxyl) spin probes has been investigated. The penetration process was followed by 360 hours at 24°C, using the electron spin resonance (EPR) method. The spectroscopic parameter of the partition (F) of this probe indicated that a maximum rigidity of the membrane was at 3% concentration of the vanadium complex. Computer simulations showed that the increase in the rigidity of the membrane corresponds to the closure of gaps in the surface layer of the membrane, and indicates the essential role of the membrane surface in transport processes.

Keywords

EN

EPR probe; lipid membrane; membrane fluidity; Monte Carlo simulation

• Publisher: De Gruyter Open
• Journal: Nukleonika
• Year: 2015
• Volume: 60
• Issue: 3
• Pages: 395-398

Dates

published

1 - 7 - 2015

accepted

16 - 4 - 2015

received

20 - 11 - 2014

online

6 - 8 - 2015

Contributors

author

Ryszard Olchawa

• Institute of Physics, Opole University, 48 Oleska Str., 45-052 Opole, Poland

author

Dariusz Man

• Institute of Physics, Opole University, 48 Oleska Str., 45-052 Opole, Poland

author

Barbara Pytel

• Institute of Physics, Opole University, 48 Oleska Str., 45-052 Opole, Poland

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Identifiers

DOI

10.1515/nuka-2015-0070