Mesoporous alumina as a biomaterial for
biomedical applications

• Authors: Elisabet Xifre-Perez , Josep Ferre-Borull , Josep Pallares , Lluis F. Marsal
• Languages of publication: EN

Abstracts

EN

Porous anodic alumina (PAA) is a biomaterial
based on a cost-effective electrochemical anodization of
pure aluminum with unique geometrical properties, i.e.,
self-ordering hexagonal pore distribution, tunable pore diameters
and interpore distances, and uniformity of the
pores in the vertical direction (nanochannels). These remarkable
properties have found important applications
in several fields such as energy storage, optics, photonics,
magnetism, catalysis and, in particular, in the
biomedicine field. In this work, we review the current
state of research and key issues on cell culture and implants,
drug delivery systems with complex release profiles
and specific action, and high efficiency and sensitivity
biosensors with different biosensing mechanisms, all
of them based on PAA. The biocompatibility, morphology
of the surface, nanoestructural engineering in-depth, surface
functionalization and coatings are discussed and analyzed
in detail.

Keywords

EN

porous anodic alumina; biocompatibility; toxicity; in vivo; in vitro; cell growth; functionalization; drugdelivery; micro and nanoparticles; biosensing

• Publisher: De Gruyter Open
• Journal: Mesoporous Biomaterials
• Year: 2015
• Volume: 2
• Issue: 1

Dates

received

23 - 6 - 2015

online

29 - 8 - 2015

accepted

6 - 8 - 2015

Contributors

author

Elisabet Xifre-Perez

• Departament
  d’Enginyeria Electrònica, Elèctrica i Automàtica, Universitat
  Rovira i Virgili, Avda. Països Catalans 26, 43007 Tarragona, Spain

author

Josep Ferre-Borull

• Departament
  d’Enginyeria Electrònica, Elèctrica i Automàtica, Universitat
  Rovira i Virgili, Avda. Països Catalans 26, 43007 Tarragona, Spain

author

Josep Pallares

• Departament
  d’Enginyeria Electrònica, Elèctrica i Automàtica, Universitat
  Rovira i Virgili, Avda. Països Catalans 26, 43007 Tarragona, Spain

author

Lluis F. Marsal

• Departament
  d’Enginyeria Electrònica, Elèctrica i Automàtica, Universitat
  Rovira i Virgili, Avda. Països Catalans 26, 43007 Tarragona, Spain

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Identifiers

DOI

10.1515/mesbi-2015-0004