Is cognitive processing affected in adults with hypospadias?: P300 study

• Authors: Hakan Tekeli , Hasan Koçoğlu , Cabir Alan , Mustafa Emir Tavşanlı , Halit Yaşar , Ercan Malkoç , Mustafa Tansel Kendirli , Ceyda Hayretdağ Örs , Ahmet Reşit Ersay , Handan Işın Özışık Karaman
• Languages of publication: EN

Abstracts

EN

Background: Hypospadias is a common urogenital
system disorder. The frenulum, which is the most
sensitive area of the glans penis, is not present in patients
with hypospadias. This may lead to a failure in sexual
and ejaculatory function, and cause emotional problems
affecting cognitive processes. Aim: We aimed to study auditory Event Related Potentials
(ERP) in patients with hypospadias to understand the
status of cognitive function. Materials and Methods: Seventeen patients with hypospadias
who presented to the Urology Outpatient Clinic
of Çanakkale Military Hospital, and 11 healthy individuals
of similar age were chosen. The auditory oddball paradigm
with ERP from the Cz and Fz head regions were
studied. The latency and amplitude of the P300 wave were
measured. Results: Both, the study and control groups consisted of
young males. Although the study group had a longer P300
latency and lower P300 amplitude when compared to control group, the results were not statistically significant
(p: 0.059 and 0.346 respectively). Conclusion: Although the results are not statistically significant,
our findings indicate that there may be cognitive
changes in patients with hypospadias. Further studies of
larger sample size and older patient cohorts are needed.

Keywords

EN

Hypospadias; Event Related Potentials-P300; Cognition

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2014
• Volume: 10
• Issue: 1

Dates

accepted

14 - 9 - 2015

received

18 - 1 - 2015

online

26 - 10 - 2015

Contributors

author

Hakan Tekeli

• GATA Haydarpaşa Eğitim Hastanesi, Department of
  Neurology, Istanbul, Turkey

author

Hasan Koçoğlu

• Gölcük Asker Hastanesi, Department of Urology,
  Kocaeli, Turkey

author

Cabir Alan

• Çanakkale Onsekiz Mart Üniversitesi,
  Department of Urology, Çanakkale, Turkey

author

Mustafa Emir Tavşanlı

• Okmeydani Education
  and Research Hospital Neurology Clinic Kaptanpasa Mahallesi
  Darülaceze Street No: 25 ZIP Code: 34384, Sisli, Istanbul, Turkey
• Okmeydanı Eğitim Araştırma Hastanesi,
  Department of Neurology, İstanbul, Turkey

author

Halit Yaşar

• Ankara Mevki Asker Hastanesi, Department of Neurology,
  Ankara, Turkey

author

Ercan Malkoç

• GATA Haydarpaşa Eğitim Hastanesi, Department of
  Urology, Istanbul, Turkey

author

Mustafa Tansel Kendirli

• GATA Haydarpaşa Eğitim Hastanesi, Department of
  Neurology, Istanbul, Turkey

author

Ceyda Hayretdağ Örs

• Çanakkale
  Onsekiz Mart Üniversitesi, Department of Neurology., Çanakkale,
  Turkey

author

Ahmet Reşit Ersay

• Çanakkale Onsekiz Mart Üniversitesi,
  Department of Urology, Çanakkale, Turkey

author

Handan Işın Özışık Karaman

• Çanakkale
  Onsekiz Mart Üniversitesi, Department of Neurology., Çanakkale,
  Turkey

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Identifiers

DOI

10.1515/med-2015-0059