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Number of results

Journal

2014 | 10 | 1 |

Article title

Inclusion body myositis – pathomechanism and lessons from genetics

Content

Title variants

Languages of publication

EN

Abstracts

EN
Inclusion body myositis is a rare, late-onset
myopathy. Both inflammatory and myodegenerative
features play an important role in their pathogenesis.
Overlapping clinicopathological entities are the familial
inclusion body myopathies with or without dementia.
These myopathies share several clinical and pathological
features with the sporadic inflammatory disease.
Therefore, better understanding of the genetic basis and
pathomechanism of these rare familial cases may advance
our knowledge and enable more effective treatment
options in sporadic IBM, which is currently considered a
relentlessly progressive incurable disease.

Publisher

Journal

Year

Volume

10

Issue

1

Physical description

Dates

received
18 - 2 - 2014
online
26 - 2 - 2015
accepted
30 - 1 - 2015

Contributors

  • Division of Neuropathology,
    Institute of Pathology
  • Institute
    of Internal Medicine, Third Department of Internal Medicine,
    Division of Clinical Immunology
  • Institute
    of Internal Medicine, Third Department of Internal Medicine,
    Division of Clinical Immunology
  • Institute
    of Internal Medicine, Third Department of Internal Medicine,
    Division of Clinical Immunology
author
  • Division of Neuropathology,
    Institute of Pathology
author
  • Department of Neurology, University of Debrecen,
    Faculty of Medicine, Debrecen, Hungary
author
  • Division of Neuropathology,
    Institute of Pathology
  • Institute
    of Internal Medicine, Third Department of Internal Medicine,
    Division of Clinical Immunology
  • University of Debrecen,
    Faculty of Medicine, Institute of Pathology, Division of Neuropathology,
    4032 Debrecen, Nagyerdei krt. 98. Tel.: + 36 52 255-248;
    e-mail: tibor.hortobagyi@kcl.ac.uk

References

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Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.-psjd-doi-10_1515_med-2015-0030
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