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2014 | 22 | 2 | 89-97

Article title

Cognitive impairment predicts social disability in persons with epilepsy

Content

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Languages of publication

EN

Abstracts

EN
Introduction. Cognitive dysfunction is one of the main comorbidities of epilepsy which co-exists with seizures and contributes to the adverse impact of the disease on employment, education and interpersonal relationships. A fundamental question regarding cognitive dysfunction in epilepsy goes as follows: in comparison to seizures, what role does cognitive dysfunction play in causing social disability? The purpose of this review was to evaluate our understanding of the role cognitive impairment plays in social disability in persons with epilepsy (PWE). We systematically searched the medical literature and identified studies which assessed the impact of seizures and cognitive function on some aspect of social disability in PWE.Results and Discussion. We identified 12 studies which adequately measured all variables in non-surgical cohorts, and 9 studies of cohorts following epilepsy surgery. We found evidence from non-surgical and from surgical series that cognitive variables strongly correlate with levels of social disability.Conclusions. We conclude that efforts to better understand the origins of cognitive dysfunction in epilepsy and subsequently at developing treatment modalities will be needed in order to reduce the degree of social disability caused by the condition.

Publisher

Year

Volume

22

Issue

2

Pages

89-97

Physical description

Dates

published
1 - 12 - 2014
online
1 - 3 - 2015
received
19 - 5 - 2014
accepted
20 - 8 - 2014

Contributors

  • Geisel School of Medicine at Dartmouth
  • Dartmouth-Hitchcock Medical Center, Geisel School of Medicine at Dartmouth
  • Geisel School of Medicine at Dartmouth

References

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Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.-psjd-doi-10_1515_joepi-2015-0016
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