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Interchangeability of three different methods of calculating Pure Tone Average in patients with vestibular schwannoma to assess the risk of surgery-related hearing loss

100%
Ochal-Choińska A., Lachowska M., Kurczak K., Niemczyk K.
Otolaryngologia Polska
|
2020
|
vol. 74(5)
11-16
EN
Background: Patients with vestibular schwannoma (VS) most commonly present with hearing threshold reduction for high frequencies and a falling type of audiometric curve. However, it is doubtful whether all Pure Tone Averages described in the literature characterize patients with VS correctly, as the type of PTA which comprises higher frequencies may be more appropriate for hearing status assessment in those patients. Aim: The aim of this study was to analyze 3 common methods of calculating Pure Tone Averages (PTA1 – 500, 1000, 2000 and 3000 Hz; PTA2 – 500, 1000, 2000 and 4000 Hz; PTA3 – 500, 1000 and 2000 Hz) and to determine which of them is the most reliable for the assessment of VS patients. Material and Methods: The study group included 86 patients operated on due to vestibular schwannoma accessed via the middle cranial fossa. Results: Regarding the method of calculating Pure Tone Averages (PTA1, PTA2 and PTA3) identical or similar correlations were found between the preoperative values of Pure Tone Averages (PTA1, PTA2 and PTA3) and surgery-related hearing loss, as well as individual parameters of audiologic tests. Conclusions: Pure Tone Averages calculated according to 3 different methods (PTA1, PTA2, PTA3) may be used interchangeably in the assessment of hearing in VS patients.
2
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Vertigo in cerebellopontine angle tumor Patients

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Zarębska-Karpieszuk P., Bartoszewicz R., Pierchała K., Niemczyk K.
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2015
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vol. 4(4)
27-31
EN
Cerebellopontine angle tumors are a group of tumors that originate from the posterior cranial fossa. Most of them are acoustic neuromas arising from the Schwann cell sheath of the vestibular branch of VIII cranial nerve. Those benign tumors usually present with unilateral hearing loss (53–57%), tinnitus (79–82%), and vertigo/imbalance (18–50%). The objective of this study was documentation-based evaluation of 53 out of 96 patients that received surgical treatment in the ENT Department of Medical University in Warsaw during the period from May 2012 to May 2014, with special consideration of vertigo/imbalance in relation to other symptoms. Statictical analysis has shown larger frequency of vertigo/imbalance in patients with mild to moderate hearing loss and positive corelation between the largest diameter of the tumor and the vestibular deficit in VNG (videonystagmography). The corelation of vestibular deficit in VNG and imbalance symptoms was only estabilished in the group with intrameatal localization of the tumor (T1).
3
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Interchangeability of three different methods of calculating Pure Tone Average in patients with vestibular schwannoma to assess the risk of surgery-related hearing loss

100%
Ochal-Choińska A., Lachowska M., Kurczak K., Niemczyk K.
Polish Journal of Otolaryngology
|
2020
|
vol. 74
|
issue 5
11-16
EN
Background: Patients with vestibular schwannoma (VS) most commonly present with hearing threshold reduction for high frequencies and a falling type of audiometric curve. However, it is doubtful whether all Pure Tone Averages described in the literature characterize patients with VS correctly, as the type of PTA which comprises higher frequencies may be more appropriate for hearing status assessment in those patients. Aim: The aim of this study was to analyze 3 common methods of calculating Pure Tone Averages (PTA1 – 500, 1000, 2000 and 3000 Hz; PTA2 – 500, 1000, 2000 and 4000 Hz; PTA3 – 500, 1000 and 2000 Hz) and to determine which of them is the most reliable for the assessment of VS patients. Material and Methods: The study group included 86 patients operated on due to vestibular schwannoma accessed via the middle cranial fossa. Results: Regarding the method of calculating Pure Tone Averages (PTA1, PTA2 and PTA3) identical or similar correlations were found between the preoperative values of Pure Tone Averages (PTA1, PTA2 and PTA3) and surgery-related hearing loss, as well as individual parameters of audiologic tests. Conclusions: Pure Tone Averages calculated according to 3 different methods (PTA1, PTA2, PTA3) may be used interchangeably in the assessment of hearing in VS patients.
4
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New directions in molecular diagnostics and therapy of vestibular schwannomas

75%
Litwiniuk M., Makuszewska M., Bartoszewicz R., Niemczyk K.
Polski Przegląd Otorynolaryngologiczny
|
2020
|
vol. 9(4)
55-59
EN
The molecular basis for the formation and growth of vestibular schwannomas (VS) has been elucidated in the recent years. The main genetic and epigenetic aberrations, changes in gene expression and specific signaling pathways involved in pathogenesis of sporadic VS and neurofibromatosis type II (NF2) have been defined. These findings facilitated the search for prognostic markers in VS and potential targets for biological therapy. This publication summarizes the main directions of research in the field of molecular diagnostics and pharmacotherapy of VS based on biological agents.
5
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Methodology for Skull Tap Vestibular Evoked Myogenic Potentials (Tap-cVEMP)

75%
Glinka P., Lachowska M., Niemczyk K.
Polski Przegląd Otorynolaryngologiczny
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2017
|
vol. 6(3)
29-33
EN
Objective: The aim of this study is to present a methodology of vestibular evoked myogenic potentials registered from sternocleidomastoid muscle (SCM) using skull tap stimulation (Tap-cVEMP) in a patient with cerebellopontine angle tumor (CPAT). Material and methods: A 23-year-old female with CPAT. The methodology of Tap-cVEMP is introduced. The results of VEMP is confronted with surgical information about the tumor. Results: The results of AC-cVEMP and Tap-cVEMP revealed the inferior vestibular nerve bundle to be affected by the tumor with intact superior bundle. Information obtained from VEMP was confirmed during surgery. Conclusion: Skull Tap Vestibular Evoked Myogenic Potentials (Tap-cVEMP) may be the useful method in the diagnostics of CPAT. AC-cVEMP and Tap-cVEMP may be helpful to evaluate the functional integrity of both vestibular nerve bundles providing the information about their involvement in the pathological process.
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