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Human diadenosine triphosphate hydrolase: Preliminary characterisation and comparison with the Fhit protein, a human tumour suppressor.

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Asensio A. C., Rodríguez-Ferrer C. R., Oaknin S., Rotllán P.
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2000
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vol. 47
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issue 2
435-441
EN
Human platelets diadenosine triphosphatase was characterised and compared with the Fhit protein, a human tumour suppressor with diadenosine triphosphatase activity. Both enzymes exhibit similar Km, are similarly activated by Mg2+, Ca2+ and Mn2+, and inhibited by Zn2+ and suramin. However, they are differentially inhibited by Fhit antibodies and exhibit differences in gel-filtration behaviour.
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