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Mechanisms of type I interferon action and its role in infections and diseases transmission in mammals

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Niedźwiedzka-Rystwej P., Tokarz-Deptuła B., Deptuła W.
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2017
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vol. 64
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issue 2
199-205
EN
Interferons (IFNs) are pivotal regulators of immunological processes. This paper describes mainly type I interferons -α and -β and their recently recounted signaling pathways, especially connected with ISGs - interferon stimulated genes, having a crucial role in regulating IFN recruitment. Moreover, the paper shows the data on the role of interferons -α and -β in infections - not only commonly known viral infections, but also bacterial, fungal and parasitic.
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