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EN
The aim of the study was to investigate the influence of kohlrabi and broccoli sprouts added to diet on the concentrations of short-chain fatty acids in faeces samples of rats with thyroid dysfunction. Two models of hypothyroidism were used. First one was based on the diet with iodine deficiency and the second by sulfadimethoxine addition to the animal drinking water. In most cases the concentrations of acetic acid, propanoic acid and butanoic acid in stool samples obtained from rats with thyroid dysfunction were insignificantly lower than found in control group. Moreover, almost in all cases the diet enriched with brassica sprouts insignificantly increased the concentration of fatty acids in investigated material. Significant positive correlation between concentrations of butanoic and acetic acids was found in different groups of rats. In conclusion, the addition of brassica or kohlrabi sprouts in rat’s diet may slightly alleviate the decline of concentrations of some fatty acids in stool of animals with thyroid dysfunction. Long term effects of this phenomenon should be evaluated in future studies.
EN
Resistant starches are type of dietary fibers. However, their physiological effects depend on the way they resist digestion in the gastrointestinal tract. The objective of this study was to examine the hypothesis that new type of RS4 preparations, of in vitro digestibility of about 50%, obtained by cross-linking and acetylation, acts as a prebiotic by increasing short chain fatty acids content in cecum digesta. The rats were fed with diet containing pregelatinized, cross-linked and acetylated starches as a main carbohydrate source. Pregelatinized, but not chemically modified, potato starch was used in the composition of the control diet. After two weeks of experiment the increase of short chain fatty acids contents in ceceum digesta was observed. The intake of starch A, cross-linked only with adipic acid, resulted in increase of about 40% of short chain fatty acids content, whereas starch PA cross-linked with sodium trimetaphosphate and adipic acid of about 50%. The utmost twofold increase was observed in the case of the production of propionic acid. In contrast, the content of butyric acid increased (12%) only as an effect of consumption of starch PA and even decreased (about 30%) in case of starch A. Both RS4 starches caused an increase of the production of acetic acid by more than 40%. No changes in serum biochemistry, liver cholesterol and organ weights of rats were stated.
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