Search results

1

Risk Factors for Wound Dehiscence after Laparotomy – Clinical Control Trial

100%

Kenig J., Richter P., Żurawska S., Lasek A., Zbierska K., Nowak W.

Polish Journal of Surgery

|

2012

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vol. 84

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issue 11

565-573

EN

Described in the literature dehiscence rate in the adult population is 0.3-3.5%, and in the elderly group as much as 10%. In about 20-45% evisceration becomes a significant risk factor of death in the perioperative period. The aim of the study was to identify the main risk factors for abdominal wound dehiscence in the adult population. Material and methods. The study included patients treated in the 3rd Department of General Surgery, Jagiellonian University Collegium Medicum in Cracow in the period from January 2008 to December 2011, in which at that time laparotomy was performed and was complicated by wound dehiscence in the postoperative period. For each person in a research group, 3-4 control patient were selected. Selection criteria were corresponding age (± 2-3 years), gender, underlying disease and type of surgery performed. Results. In 56 patients (2.9%) dehiscence occurred in the postoperative period with 25% mortality. The group consisted of 37 men and 19 women with the mean age of 66.8 ± 12.6 years. Univariate analysis showed that chronic steroids use, surgical site infection, anastomotic dehiscence/fistula in the postoperative period and damage to the gastrointestinal tract are statistically significant risk factors for dehiscence. Two first of these factors occurred to be independent risk factors in the multivariate analysis. In addition, due to the selection criteria, a group of risk factors should also include male gender, emergency operation, midline laparotomy, colorectal syrgery and elderly age (> 65 years). Logistic regression analysis did not show that a particular surgeon, time of surgery or a particular month (including holiday months) were statistically significant risk factor for dehiscence. Conclusions. Wound dehiscence is a serious complication with relatively small incidence but also high mortality. Preoperative identification of risk factors allows for a more informed consent before patient’s treatment and to take measures to prevent or minimize the consequences of complication associated with it.

2

Risk factors of 30-day mortality following surgery for colorectal cance

80%

Mik M., Dziki Ł., Trzciński R., Dziki A.

Polish Journal of Surgery

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2016

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vol. 88(1)

26-31

EN

The 30-day mortality is one of the factors reflecting the quality of treatment. All these efforts focused on decreasing 30-day mortality will directly improve quality of care. The aim of the study was to identify risk factors of 30-day postoperative mortality in a cohort of patients operated on for colorectal cancer in one tertiary colorectal centre. Material and methods. Patients operated on due to colorectal cancer (CRC) between 2008 and 2014 were included in the study. 30-day mortality was assessed as an endpoint of the retrospective study. All records were collected from prospective database. Results. 1744 patients were operated on due to CRC. The 30-day mortality was noted in 65 patients (3.5%). In multivariable analyses we revealed that spread disease and poor general condition at admission were risk factors of 30-day mortality: OR 2.35; 2.01‑2.57 95%CI, p=0.03 and OR 2.18; 1.95‑2.41 95% CI; p=0.01, respectively. Emergency surgery significantly increased the risk of 30-day mortality: OR 2.64; 2.45‑2.87 95%CI; p=0.009. Low serum albumin concentration level and diabetes mellitus were additional risk factors for 30-day mortality, OR 1.65; 1.52‑1.78 95%CI; p=0.01 and OR 1.67; 1.41‑1.82 95%CI; p=0.03, respectively. Mortality was significantly higher after resection procedures than after only palliative operations: 4.21% vs 1.57%; p=0.002. Conclusions. Emergent patients, patients with advanced disease and in poor general state have to be assessed by multidisciplinary team to prepare them to operation. Additionally to reduce the risk of 30-day mortality decision of extend of surgery should be made by experienced surgeons.

3

Hypoalbuminemia as a relapse risk factor after high dose chemotherapy and autologous stem cell transplantation in patients with Hodgkin’s lymphoma

80%

Koźlik P., Długosz-Danecka M., Pacholczak R., Bryk A., Krawczyk A., Jurczak W.

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vol. 8

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issue 4

114-119

EN

Assessing the risk factors according to EORTC (European Organization of Research and Treatment of Cancer) or HD IPS (Hodgkin’s lymphoma International Prognostic Score) is crucial for choosing the adequate I line therapy in Hodgkin’s lymphoma patients. However, none of those scales predicts the efficacy of autologous stem cell transplant (ASCT) in relapsing/refractory (R/R) patients. Progression- free survival (PFS) after ASCT corelates with the response to salvage regimens. Thirty-nine Hodgkin’s lymphoma patients transplanted at Jagiellonian University Department of Hematology with a follow-up exceeding 5 years were analyzed. Despite long time periods since the diagnosis, initial serum albumin levels seem to correlate with progression after autologous stem cell transplant and indicate high probability of relapse within 5 months following the procedure with favorable test characteristics.

4

Analysis of risk factors for oral cavity and oropharynx cancer in the authors’ own material

80%

Nowosielska-Grygiel J., Owczarek K., Bielińska M., Wacławek M., Olszewski J.

Otolaryngologia Polska

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2017

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vol. 71(2)

23-28

EN

Introduction: The aim of the study was to analyse the risk factors for oral cavity and oropharynx cancer in peopled examined under the Head and Neck Cancer Awareness Week in 2016, Lodz. Material and methods. In Lodz, 21st September 2016, under the Head and Neck Cancer Awareness Week, 106 people, including 67 women aged 29–77 and 39 men aged 23–84, underwent preventive examinations in the hospital department. Prior to the laryngological examination, the patients were asked to answer questions that referred to their education, medical case history, symptoms, smoking habits with the number of cigarettes per day, alcohol intake, the number of lifetime sexual partners, oral sex engagement, incidents of head and neck cancer in the family history. Results: The major part of the examined patients were women and men with the secondary and high level of education, 47,76% and 35,82%, and 58,97% and 35,91% respectively. The patients were informed by mass media about the planned preventive medical examinations – 80,60% women and 79,49% men. The most common symptoms reported by women were: hoarse voice in 61,19% cases, dysphagia in 32,84% cases and burning sensation and/or pain in the oral cavity in 29,85% cases. The examined male patients mainly showed hoarse voice (46,15%), other symptoms (43,59%) and dysphagia (25,64%). 28,35% women and 28,20% men smoked cigarettes, while passive smokers were 22,38% and 25,64% respectively. Alcohol consumption was reported by 67,16% women and 82,05% men, rather occasionally. Having oral sex was noted in 25,37% women and 38,46% men, mostly with multiple sexual partners. Among the studied patients, 13,43% women and 5,12% men suffered from malignant cancer, including 2,98% women and 2,56% men who reported head and neck carcinoma in the medical interview. On the basis of the interview and ENT examination, 11,94% women and 17,94% men were qualified for the extended oncological diagnostics. Conclussion. The Fourth Head and Neck Cancer Awareness Week shows the increased interest in preventive screening, especially oncological screening, and thus the necessity of such preventive activities in the future.

5

Analysis of risk factors for oral cavity and oropharynx cancer in the authors’ own material

80%

Nowosielska-Grygiel J., Owczarek K., Bielińska M., Wacławek M., Olszewski J.

Polish Journal of Otolaryngology

|

2017

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vol. 71

|

issue 2

23-28

EN

Introduction: The aim of the study was to analyse the risk factors for oral cavity and oropharynx cancer in peopled examined under the Head and Neck Cancer Awareness Week in 2016, Lodz. Material and methods. In Lodz, 21st September 2016, under the Head and Neck Cancer Awareness Week, 106 people, including 67 women aged 29–77 and 39 men aged 23–84, underwent preventive examinations in the hospital department. Prior to the laryngological examination, the patients were asked to answer questions that referred to their education, medical case history, symptoms, smoking habits with the number of cigarettes per day, alcohol intake, the number of lifetime sexual partners, oral sex engagement, incidents of head and neck cancer in the family history. Results: The major part of the examined patients were women and men with the secondary and high level of education, 47,76% and 35,82%, and 58,97% and 35,91% respectively. The patients were informed by mass media about the planned preventive medical examinations – 80,60% women and 79,49% men. The most common symptoms reported by women were: hoarse voice in 61,19% cases, dysphagia in 32,84% cases and burning sensation and/or pain in the oral cavity in 29,85% cases. The examined male patients mainly showed hoarse voice (46,15%), other symptoms (43,59%) and dysphagia (25,64%). 28,35% women and 28,20% men smoked cigarettes, while passive smokers were 22,38% and 25,64% respectively. Alcohol consumption was reported by 67,16% women and 82,05% men, rather occasionally. Having oral sex was noted in 25,37% women and 38,46% men, mostly with multiple sexual partners. Among the studied patients, 13,43% women and 5,12% men suffered from malignant cancer, including 2,98% women and 2,56% men who reported head and neck carcinoma in the medical interview. On the basis of the interview and ENT examination, 11,94% women and 17,94% men were qualified for the extended oncological diagnostics. Conclussion. The Fourth Head and Neck Cancer Awareness Week shows the increased interest in preventive screening, especially oncological screening, and thus the necessity of such preventive activities in the future.

6

Predictive factors for preeclampsia in pregnant women: a unvariate and multivariate logistic regression analysis

80%

Direkvand-Moghadam A., Khosravi A., Sayehmiri K.

|

2012

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vol. 59

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issue 4

673-677

EN

Introduction: Several risk factors have been used to predict preeclampsia. The role of some risk factors as predictors associated with preeclampsia among Iranian women was analyzed in the present study using logistic regression. Materials and Methods: 610 women attending the obstetric ward of Mustafa hospital in Ilam were enrolled in this study. Demographic variables such as age, Body Mass Index (BMI), medical and obstetrics variables such as education, number of pregnancy, abortion and parity from May to September 2010 were analyzed. We used the unvaried and multiple logistic regression analyses to predict preeclampsia. Results: The history of preeclampsia, hypertension, and infertility showed to be good independent predicator variables for preeclampsia using multivariate logistic regression analysis (OR was 5.46, 2.34 and 3.07 respectively). Area Under the Receiver Operation Character (AUROC) was estimated to be 0.67 (95% CI 0.59-0.67, p<0.01) indicating the efficacy of the model for the prediction. Conclusion: The history of preeclampsia, hypertension and infertility predict preeclampsia with an increased odds ratio. Using such variables in regression analysis can help to diagnose preeclampsia beforehand and hence allow timely intervention.

7

The effectiveness of screening for major cardiovascular risk factors in the population of small towns in Poland

80%

Rutkowski M., Wierucki Ł., Wojciechowska A., Zdrojewski T.

European Journal of Translational and Clinical Medicine

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2021

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vol. 4

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issue 1

57-64

EN

Background: Screening represents an important tool to improve detection of cardiovascular risk factors. Uniform standards for screening programs and for evaluation of their effectiveness are still lacking. Material and methods: The results of the Polish 400 Cities Project (P400CP) were analyzed by age and gender, and with regard to the prevalence and awareness of cardiovascular risk factors. The P400CP population were volunteers reporting for screening tests in small towns, and a representative sample was used as control. Results: Mean age in the screening group was 10 years more than in the representative sample. Two thirds of participants were women. First-time diagnosis rates for elevated arterial blood pressure, hyperglycemia and hypercholesterolemia in the screening were 28%, 15% and 51%, respectively. Almost 40% of participants reported previously diagnosed hypertension (vs. 25% of the control sample), 7% vs. 4% reported diabetes and 16% vs. 9% – hypercholesterolemia. Smokers represented 16.5% of participants (36% of the control sample). Conclusions: “Open” screening programs fail in targeting young adults, especially males, and people reporting for screening are often already diagnosed with arterial hypertension and/or diabetes. Despite these limitations, “open” screening is effective in detecting undiagnosed cases of hypercholesterolemia. Non-smokers report for screening tests more often.

8

Clostridium difficile infection in patients hospitalized in the gastroenterology ward – retrospective analysis

80%

Podlaszewska K., Ewa M. P., Gąsiorowska A.

Polish Journal of Surgery

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2018

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vol. 90(1)

7-12

EN

INTRODUCTION. Clostridium difficile associated colitis became over last years a worldwide medical issue. It involves patients of the Polish hospitals too. The aim of the study was the analysis of CDAD incidence and the course of infection in Gastroenterology Ward of Regional Specialist Hospital of Zgierz, 2012-2015. MATERIAL AND METHODS. Retrospective analysis of the medical documentation of 79 patients with CDAD was performed. Demographic and epidemiological data and the clinical course of infection were analyzed. RESULTS. The study group comprised of women in 59,5% and men in 40,5%. The patients’ average age was 70,5 years. The average hospitalization period was 10,3 days. CDAD infection seasonality was proved, with statistically significant peak in springtime. 73% of patients were previously hospitalized and 85% - had co-morbidities. 76% of patients underwent antibiotherapy, whilst 29% - used PPI prior to CDAD diagnosis. 50,6% of patients had severe CDAD diagnosed. The recurrence reached 14%. In 19% of patients CDAD resulted in death. DISCUSSION. The results of the study confirm increase of the incidence of the patients with CDAD in Gastroenterology Ward over 4-years’ observation. The prevalence was higher among 65+ patients, after prior hospitalization and antibiotherapy. The co-morbidities was a significant risk factor, especially common in severe cases. CONCLUSION. The results we obtained confirm substantial importance of Clostridium difficile infection leading to antibiotherapy-associated diarrhea among adults, causing prolonged hospitalization, increased prevalence and mortality of patients. Getting to know and minimizing the risk factors will prevent the future outbreak of the disease.

9

Follow-up on the diagnostic level of children covered by the Universal Neonatal Hearing Screening Program in Poland, divided into voivodships

80%

Greczka G., Zych M., Dąbrowski P., Gasińska A., Król A., Szyfter-Harris J., Szyfter W.

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vol. 73(4)

1-7

EN

Introduction: Thanks to the Polish Universal Neonatal Hearing Screening Program (PUNHSP), all newborns in Poland undergo a free, screening hearing examination. Between 2006 and 2015, the average number of tested children per year was 373,477. According to the analysis of The Central Database (CDB), only 55.8% of the children attended the detailed hearing examinations at the second level of the Program. Aim: The aim of this study is to analyse the dates concerning the attendance of the children at the diagnostic level of PUNHSP in different regions of Poland. Materials and methods: To conduct an analysis of this fact and find out the reasons for low attendance at the second level in 2015, a telephone survey questionnaire was developed for parents who had not registered their babies for further consultation – 3,239 randomly selected parents. Results: The analysis revealed that the number of children examined at the second diagnostic level of the program is in fact much higher than the results of The Central Database show. The actual number is 83.6% as opposed to 55.8%. As a result of the telephone questionnaire some inaccuracies in the input data to the CDB were detected. The main errors in gathering the information for the CDB were incorrect OAE test result and no examination performed. C onclusion: In Poland the worst results (i.e. questionnaire results compared to CDB) for the attendance at the diagnostic level were shown in Pomorskie, Lubelskie, Mazowieckie and Podlaskie regions. In many cases there was a large discrepancy between the reality and the information in the CDB. The improvement of clarity concerning the CDB application is important in order to minimise the possibility of malformation in the CDB.

10

Retrospective evaluation of risk factors for oral cavity and oropharynx cancers in patients under the program of head and neck cancers prevention

80%

Kowalski A., Olszewski J., Zielińska-Bliźniewska H.

Polish Journal of Otolaryngology

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2019

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vol. 73

|

issue 6

24-31

EN

Introduction: The aim of the study was to analyze the risk factors for oral cavity and pharyngeal cancer in people examined under the Head and Neck Cancer Prophylaxis Program. Material and methods: The study was conducted in a total of 300 patients, including 186 women and 114 men, as part of the Head and Neck Cancer Prevention Program in 2014–2018. Before the laryngological examination, the patients completed a demographic and medical questionnaire regarding the risk factors of head and neck cancer, including education, reported disease symptoms, smoking addiction, number of cigarettes smoked daily, alcohol consumption, frequency of visits in a dental office, oral hygiene measures, number of sexual partners, oral sex, family medical history of head and neck cancer. Results: The subjects reported the following symptoms: hoarseness 43.33%, difficulty swallowing 21.33%, pain or mouth burning 20.33% and other symptoms were observed in 46.33%. The main dental symptoms were: bleeding from the gums during teeth brushing in 48.89%, dry mouth 45.56%. Currently 20.33% of respondents smoke, whereas 54% of patients smoked in the past. In the analyzed material, the majority (80%) consumed alcoholic beverages. 27.67% of respondents admitted having oral sex, including 24.73% of women and 32.46% of men. After performing the extended diagnostics, the tumor was found in 10% of the subjects. C onclusions: Statistical significance of differences was found: between hoarseness and alcohol consumption, both in women and in men, between hoarseness and smoking in women, between difficulty in swallowing and smoking in women, between burning/pain in the mouth and smoking in men, between hoarseness and the cultivation of oral sex in men, between the difficulty of swallowing and the practice of oral sex in the studied men and between burning/pain in the oral cavity and the occurrence of malignancy.

11

The Influence of Selected Risk Factors on the Hearing Threshold Level of Noise Exposed Employees

80%

Dudarewicz A., Toppila E., Pawlaczyk-Łuszczyńska M., Śliwińska-Kowalska M.

Archives of Acoustics

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2010

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vol. 35

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issue 3

12

The influence of risk factors associated with lifestyle on the development of breast cancer

80%

Szeja N., Słoma M.

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vol. 8

|

issue 4

137-144

EN

Breast cancer is the most common result of mutual correlation between hormonal determinants, environmental and genetic. Mechanisms of its development include: high estrogen concentration, impaired glucose metabolism, hyperglycemia, hyperinsulinemia, high levels of insulin-like growth factor 1, persistent inflammation and oxidative stress, and impaired cellular apoptosis. The aim of the study was to analyze data on the risk factors of breast cancer, which have been divided according to the period of diagnosis for pre-menopausal and postmenopausal. Due to the fact that a large part of the determinants of the occurrence of this cancer is modifiable, it is necessary to raise the awareness of the population about it. Maintaining proper body mass through the use of a balanced diet rich in calcium, non-starch vegetables and products rich in carotenoids, while limiting alcohol consumption and care for physical activity, are the best prevention of breast cancer. At the same time, further research is needed to explain the uncertainty of current observations.

13

An Association of ARG399GLN Polymorphism ofXRCC1Gene with a Risk of Colorectal Cancer

80%

Kabziński J., Przybyłowska K., Mik M., Sygut A., Dziki Ł., Dziki A., Majsterek I.

Polish Journal of Surgery

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2010

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vol. 82

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issue 12

677-680

EN

Colorectal cancer is one of the most commonly diagnosed cancer and a leading cause of death from cancer. DNA repair defects have been associated with an individual susceptibility to cancer. Therefore, polymorphisms of DNA repair genes, including XRCC1 gene, are suspected to may increase the risk of colorectal cancer.The aim of the study was to examine the association between Arg399Gln polymorphisms of XRCC1 gene and the occurrence of colorectal cancer. Research and understanding of the molecular basis of the formation of colorectal cancer will allow for typing of genetically loaded persons and qualifying them to a high-risk group.Material and methods. In case-control study we genotyped 150 colorectal cancer patients and 170 healthy subjects from Polish population. Analysis was performed by PCR-restriction fragment length polymorphism (PCR-RFLP).Results. We found that Gln/Gln genotype is associated with increased risk of colorectal cancer (OR 1.984; Cl 95% 1.070-3.677; p=0.029). We also found that Arg/Gln genotype is a risk factor for progression of tumor growth (OR 3.52; Cl 95% 1.157-10.707; p=0.023).Conclusions. The current state of research suggests a link between Arg399Gln XRCC1 polymorphism and increased risk of colorectal cancer. Therefore, we conclude that the Arg399Gln polymorphism of XRCC1 gene may underlie at the molecular basis of the causes of colorectal cancer.

14

Life hazard ratio – a new scale for assessing the severity of injury in the populetionalstud

80%

Nogalski A., Lűbek T., Ochal A., Jojczuk M.

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vol. 85

|

issue 7

381-386

EN

The heterogeneous population of patients affected by trauma is extremely difficult to systematize. This is due to the diversity of mechanisms of injury, the nature and severity of the injury and the population, which relate to injuries, diverse in terms of gender, age, presence of comorbidities that make up the final severity of the injury and a certain degree of danger to life. The aim of the study was to develop a universal method to assess the severity of injury and loss of life resulting from their consequences, using the parameters available in the Polish administrative databases, a similar diagnostic efficacy as other used scales to assess the severity of damage. Material and methods. The study analyzed a group of 92 463 patients hospitalized due to injuries sustained as a result of injuries in all hospitals of the Lublin region in 2003-2005. Developed catalogs risk factors, reference to the population of the Lublin province. Results. Developed five models predictive of injury severity scale counterparts, which include different combinations of risk factors associated with the type of injury, age of the patient and the mechanism of injury that have been evaluated for their diagnostic efficacy in differentiating the expected outcomes. Prediction model have the best diagnostic efficacy AUROC 0.9615, SE 0.0025 and 95% CI 0,9565-0,9665, hereinafter referred to as Life Hazard Ratio (LHR), which has a similarly high diagnostic efficacy as the other, examined in the work of the rock assess the severity of damage AUROC 0.9585, SE 0.0368, 95% CI0 0.8849-1. Conclusions. 1. The proposed method of use of the International Classification ICD-10 allows the use of regional administrative databases to conduct detailed analyzes of population and monitor trends in the epidemiology of injuries. 2. Developed Life Hazard Ratio (LHR)is a universal method for the objective evaluation of the severity of injuries and the associated risk of life-threatening, can also conduct population studies. 3. LHR has a comparable rate of diagnostic efficacy as other commonly used scales assessing the severity of the injury.

15

An analysis of factor infl uencing the outcome of patients with locally advanced larynx cancer

80%

Kubrak J., Jarema A., Falco M., Rogowska D., Rubik A., Torbé B.

Otolaryngologia Polska

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2008

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vol. 62(6)

691-694

EN

Purpose. Results of treatment of locally advanced larynx cancer T3-4No-4 are unsatisfi ed. The aim of study is analysis of risk factors. Methods and Materials. 112 patiens with larynx cancer after radical surgical treatment had postoperative radiotherapy (conventional or accelarated). Results. The 3-year overall survival (OS) was 58%. Margin status and numer of risk factors had impast on OS. The 3-year locoregional control (LRC) was 80%. Number of risk factors, level of hemoglobin, overall tratment time and dose were signifi cantly associated with LRC. Incidence of distant metastases was asssociated with G3 suamous cell carcinoma and index of nalignancy H. Glanz.

16

Gender-related incidence, risk factors exposure and survival rates of laryngeal cancers – the 10-years analysis of trends from one institution

80%

Majszyk D., Bruzgielewicz A., Osuch-Wójcikiewicz E., Rzepakowska A., Niemczyk K.

Polish Journal of Otolaryngology

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2019

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vol. 73

|

issue 3

6-10

EN

Objectives: The aim of the study was the analysis of the epidemiology of laryngeal cancer over 10 years in relation to known risk factors and to assess the current survival rates in this group of patients. Methods: The data were retrospectively collected from patients’ medical records, then entered in the database using dedicated software and a statistical analysis was performed. Results: 512 subjects - 443 men (86.5%) and 69 women (13.5%) were enrolled into the study. The male-to-female ratio was 6.4:1. There were 97.1% smoking women and 98% smoking men, however the history of more than 20 cigarettes per day smoking admitted 81.1 % of women and 94.6% of men. Heavy alcohol consumption was the case in 14 (20.3%) women and in 307 (69.3%) men. For both the size of heavy alcohol consumption and the size of excessive tobacco use, there was found statistically significant difference between women and men with laryngeal cancer (p<0.05). In the majority of male and female subjects, the tumour was located in the supraglottis/glottis area. Apparently this tumour location was much more common among women, accounting for 60.9% of cases , while in men was confirmed in 39.3% of cases. The stages of the laryngeal cancer were similarly of high advancement for both the men and women - stages III and IV were confirmed in 82.6% of women and in 77.6% of men. The over 5-year survival rate was 39.1% among women and 37.2% among men. Conclusions Contradictory to decreased exposure to risk factors and the shorter period for diagnosis, the higher stages of cancer were observed in women. Although in women the advancement was higher and the majority of cases were located in unfavourable supraglottic area, the survival rates were higher. Key words: laryngeal cancer, epidemiology, men and women, risk factors

17

Follow-up on the diagnostic level of children covered by the Universal Neonatal Hearing Screening Program in Poland, divided into voivodships

80%

Greczka G., Zych M., Dąbrowski P., Gasińska A., Król A., Szyfter-Harris J., Szyfter W.

Polish Journal of Otolaryngology

|

2019

|

vol. 73

|

issue 4

1-7

EN

Introduction: Thanks to the Polish Universal Neonatal Hearing Screening Program (PUNHSP), all newborns in Poland undergo a free, screening hearing examination. Between 2006 and 2015, the average number of tested children per year was 373,477. According to the analysis of The Central Database (CDB), only 55.8% of the children attended the detailed hearing examinations at the second level of the Program. Aim: The aim of this study is to analyse the dates concerning the attendance of the children at the diagnostic level of PUNHSP in different regions of Poland. Materials and methods: To conduct an analysis of this fact and find out the reasons for low attendance at the second level in 2015, a telephone survey questionnaire was developed for parents who had not registered their babies for further consultation – 3,239 randomly selected parents. Results: The analysis revealed that the number of children examined at the second diagnostic level of the program is in fact much higher than the results of The Central Database show. The actual number is 83.6% as opposed to 55.8%. As a result of the telephone questionnaire some inaccuracies in the input data to the CDB were detected. The main errors in gathering the information for the CDB were incorrect OAE test result and no examination performed. C onclusion: In Poland the worst results (i.e. questionnaire results compared to CDB) for the attendance at the diagnostic level were shown in Pomorskie, Lubelskie, Mazowieckie and Podlaskie regions. In many cases there was a large discrepancy between the reality and the information in the CDB. The improvement of clarity concerning the CDB application is important in order to minimise the possibility of malformation in the CDB.

18

Modern Factors of Health and Their Peculiarities for Teenagers

80%

Surmach M. J., Tishchenko E., Piecewicz-Szczęsna H.

Polish Journal of Public Health

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2015

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vol. 124

|

issue 3

152-155

EN

The work aimed at specifying modern features of civilizational factors influence on the health, revealing peculiarities of young age, establishing reflexion of modern factors of health in methodological approaches to health studying. Changes in understanding health are reflected in its studying methodology. The analysis of sociological research data shows, that the social stress became the main reason of medical-demographic situation deterioration in days of reforms. The mechanism of its influence was the loss of effective labor motivation, social envy, and deterioration of spiritual condition of a society. Material well-being decrease was not a determinative factor. The problem of inequalities in health gets the increasing urgency. It is connected with physical and social living environment; availability of qualitative medical aid; specific features of behavior of people. At a medical aid guarantee, and at teenage age, factors of social living environment, which influence behavior in health sphere by means of stigmatization are especially significant.

19

Trends in the treatment of risk factors for stroke in a Czech stroke unit

80%

Simunek L., Krajickova D., Vysata O., Valis M.

Open Medicine

|

2014

|

vol. 10

|

issue 1

EN

The goal of this study is to evaluate therapeutic trends for several diseases that represent risk factors for stroke. The relative frequency of therapy with compounds that influence the risk factors for stroke was monitored in a group of 3,290 patients who were hospitalised in the Stroke Unit at the University Hospital in Hradec Kralove between 2005 and 2012. For most drugs monitored, the reasons for the significant decrease or increase in use were causes other than the reduction of stroke risk. Despite this finding, the majority of statistically significant changes had, according to review of comparative studies, a posi- tive effect on prevention of stroke. Motivation to change treatment of stroke risk factors, such as hypertension, diabetes mellitus and hypercholesterolemia, was mainly aimed at sufficient disease management with a minimum of adverse effects. On the other hand, optimization of stroke recurrence and economic factors were motivations to treatment changes in prevention with antiplatelets. Antidiabetics were associated with an increase in met- formin use and reduction in insulin use. For antihyperten- sives, the most significant reduction was associated with the use of diuretics, although calcium channel blockers and beta-blockers are also less used. Additionally, the use of the ACE inhibitor ramipril increased

20

Retrospective evaluation of risk factors for oral cavity and oropharynx cancers in patients under the program of head and neck cancers prevention

80%

Kowalski A., Olszewski J., Zielińska-Bliźniewska H.

Otolaryngologia Polska

|

2019

|

vol. 73(6)

24-31

EN

Introduction: The aim of the study was to analyze the risk factors for oral cavity and pharyngeal cancer in people examined under the Head and Neck Cancer Prophylaxis Program. Material and methods: The study was conducted in a total of 300 patients, including 186 women and 114 men, as part of the Head and Neck Cancer Prevention Program in 2014–2018. Before the laryngological examination, the patients completed a demographic and medical questionnaire regarding the risk factors of head and neck cancer, including education, reported disease symptoms, smoking addiction, number of cigarettes smoked daily, alcohol consumption, frequency of visits in a dental office, oral hygiene measures, number of sexual partners, oral sex, family medical history of head and neck cancer. Results: The subjects reported the following symptoms: hoarseness 43.33%, difficulty swallowing 21.33%, pain or mouth burning 20.33% and other symptoms were observed in 46.33%. The main dental symptoms were: bleeding from the gums during teeth brushing in 48.89%, dry mouth 45.56%. Currently 20.33% of respondents smoke, whereas 54% of patients smoked in the past. In the analyzed material, the majority (80%) consumed alcoholic beverages. 27.67% of respondents admitted having oral sex, including 24.73% of women and 32.46% of men. After performing the extended diagnostics, the tumor was found in 10% of the subjects. C onclusions: Statistical significance of differences was found: between hoarseness and alcohol consumption, both in women and in men, between hoarseness and smoking in women, between difficulty in swallowing and smoking in women, between burning/pain in the mouth and smoking in men, between hoarseness and the cultivation of oral sex in men, between the difficulty of swallowing and the practice of oral sex in the studied men and between burning/pain in the oral cavity and the occurrence of malignancy.

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Risk Factors for Wound Dehiscence after Laparotomy – Clinical Control Trial