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EN
Background: Hyperbaric therapy is a relatively new non-invasive therapeutic method. It involves inhaling the patient with pure oxygen using a pressure of 2 to 3 absolute atmospheres (ATA). The main purpose of this therapy is to improve the healing mechanisms and repairing processes in the case of various types of wounds and diseases. While in medicine this method is quite popular, in sport it is rarely used today and if so than mainly for the purposes of faster return to full fitness of athletes after injuries or after heavy, intense training conditions. Case study: Two subjects took part in the experiment. Training sessions were performed based on the selected original set of exercises within 29 days. Experiment participant was under conditions of increased pressure (2.5 ATA), during the session he breathed 100% oxygen, provided by the individual respiratory system. The measurement of muscle strength level of selected muscle groups, in selected motor tasks was estimated in (maximum weight – which is the maximum external resistance defeated in one repetition). It was found that there were increases in the level of muscle strength in selected muscles groups in first participant as a result of the applied set of exercises (motor tasks) and the effect of the hyperbaric sessions. Conclusions: The results of the study show that there was a visible/significant influence of the hyperbaric session on increasing the muscle function based on strength training example. This method in combination with adequate strength training sessions could be used in many areas connected with psychomotor development of human abilities.
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Anomalously large kinetic isotope effect

100%
Open Chemistry
|
2007
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vol. 5
|
issue 4
1019-1063
EN
Activated diffusion of water between macromolecules in swollen cellulose is accompanied by anomalously high kinetic isotope effects of oxygen. The separation factor of heavy-oxygen water (H218O /H216O) is thousands of permilles instead of tens of permilles according to modern Absolute Rate Theory. This anomalous separation under usual conditions is disguised by the opposing process of very fast equalization to equilibrium through water-filled cellulose pores. This process is quicker by approximately 3 orders of magnitude than diffusion through the cellulose body. As a consequence, this opposition-directed equalization virtually eliminates the results of isotope separation. To reveal this anomaly it is necessary to suppress equalization, which was the primary problem for both discovery of this anomaly and its investigation. The method of investigating the anomalous separation in cellulose was developed with suppression of this negative influence. Discussion of the theoretical nature of the anomalous kinetic isotope effect is presented. This theoretical study would probably permit the discovery and use for isotope separation of the anomalously high isotope effect for other chemical elements, in particular, for those heavier than oxygen. [...]
EN
COVID pandemic has been a cause of extensive morbidity and mortality worldwide. Patients with severe COVID have been observed to suffer from remnant lung damage, fibrosis and oxygen dependency. These patients have still an unpredictable course and outcome. The outcome of these patients is not clearly defined yet. The signs and symptoms in such patients persisting even 4 weeks after acute COVID-19 has been recently named as "Long COVID". In the present case series, we present the course and outcome of two such ‘Long COVID’ patients who presented with severe hypoxemic respiratory failure. These patients were managed with a prolonged application of Non-invasive ventilation with high flow oxygen and alongwith glycaemic control, steroids and antibiotics. The patients showed tremendous response to the treatment and could be weaned from NIV after about three weeks of therapy. These cases demonstrate the utility of NIV, even in severe hypoxemic respiratory failure, in Long COVID.
PL
Pandemia COVID była przyczyną rozległej zachorowalności i śmiertelności na całym świecie. Zaobserwowano, że pacjenci z ciężkim COVID cierpią z powodu resztkowego uszkodzenia płuc, zwłóknienia i uzależnienia od tlenu. Ci pacjenci nadal mają nieprzewidywalny przebieg choroby i jej zakończenie. Wynik końcowy tych pacjentów nie jest jeszcze jasno określony. Oznaki i objawy u takich pacjentów utrzymują się nawet 4 tygodnie po ostrym COVID-19, co zostało niedawno nazwane "Długim COVID". W niniejszej serii przypadków przedstawiamy przebieg i wyniki dwóch pacjentów z "długim COVID", u których wystąpiła ciężka hipoksemiczna niewydolność oddechowa. Pacjenci ci byli leczeni z przedłużonym zastosowaniem wentylacji nieinwazyjnej z wysokim przepływem tlenu, wraz z kontrolą glikemii, sterydami i antybiotykami. Pacjenci wykazali się niesamowitą odpowiedzią na leczenie i można było odstawić NIV po około trzech tygodniach terapii. Te przypadki pokazują użyteczność NIV, nawet w ciężkiej hipoksemicznej niewydolności oddechowej, w przewlekłym COVID.
EN
Introduction: The goal of our study was to identify and compare impact of specific dual focus of concen tration known in Goju - ryu school as a system of KZR (closed hands kata) - heishu, conce ntration inside the body versus KOR (open hands kata) - kaishu, conce ntration outside of the body . Method: . St udysample consisted of Karate Dojo Pivovarník karateka from Hanušovce nad Topľou, Slovak republic (n=7, 6 m en and 1 woman), all of them were holders of at least . 1 st . Dan maste r grade, they were able to practice in dual focus. We h ave compared the trainings performed by both system s KZR vs. KOR while respecting relatively identical co nditions. At the same time we observed physiologi cal, biochemical and somatic indicators. P articipants completed a questionnaire , consent form and filled out personality questionna ire . The data were evaluated with statistical programs MS Excel, SPSS Statistics, bio chemical results were obtained in laboratory Synlab Sl ovakia s.r.o, Prešov and the data were ca lculated by Dorste, Planta  14  . To determine the significance of difference s at entrances and exits KZR vs. KOR we used the Mann - Whitne U – test and Wilco xon test . S tatis tical significance was set at (p < 0. 01 , p < 0.05). Result: We assumed that the dual concentration will not ca use any significant differences from training KZR com pare to KOR. However, that was not confirmed. We have detected several statistically significant physiological biochemical and somatic differences. Summary: Our results po int to the possibility of efficiency gains and prediction in g training (performance, i ntensity etc. ). Nevertheless, this pilot study does not allow the results to be generalized for relatively small sample size , and the number of such studies, in spite of thisour study points out the high potential and possible future objectification.
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2000
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vol. 47
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issue 1
201-207
EN
It is shown that oxygen is not absolutely needed for stress-induced synthesis of catalase T in the yeast Saccharomyces cerevisiae. Yeast cells develop heat resistance after exposure to elevated temperatures in anoxia. The levels of catalase activity and thermotolerance are comparable to those in aerobically stressed cells. While these results obviously do not exclude a stress signaling role of reactive oxygen species in some systems, as postulated by other authors, they suggest that the question of the obligatory requirement for reactive oxygen species in other stress signaling systems should be rigorously re-investigated.
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