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Liver injury during long-term Aspirin Treatment After Desensitization (ATAD) in a patient with nonsteroidal anti-inflammatory drugs-exacerbated respiratory disease (N-ERD) – A case report

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Frachowicz K., Wardzyńska A., Sajna A., Makowska J. S., Kowalski M. L.
Alergia Astma Immunologia - przegląd kliniczny
|
2019
|
vol. 24
|
issue 1
30-32
EN
We report a case of a 65-year-old woman with respiratory problems increased by N-ERD, who after 9 years of daily intake of 650 mg of aspirin after desensitization experienced a significant liver enzymes elevation, consistent with drug-induced liver injury. Clinical symptoms of liver injury and elevated serum transaminases levels resolved after aspirin intake discontinuation.
PL
W pracy przedstawiono opis przypadku 65-letniej kobiety z chorobą dróg oddechowych zaostrzaną przez NLPZ (N-ERD, astma aspirynowa), u której po dziewięciu latach codziennego przyjmowania aspiryny w dawce 650 mg wystąpił istotny wzrostu stężenia enzymów wątrobowych wskazujący na polekowe uszkodzenie wątroby. Kliniczne i enzymatyczne cechy uszkodzenia wątroby ustąpiły po zaprzestaniu przyjmowania aspiryny.
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