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in the keywords:  nematodes; choline metabolism; phosphatidylcholine biosynthesis
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2003
|
vol. 50
|
issue 4
1239-1243
EN
Nematodes were found to synthesize phosphorylcholine-containing molecules not present in higher organisms, i.e. phosphorylcholine-substituted glycosphingolipids and (glyco)proteins. Investigations on the biosynthesis of these structures provided first biochemical evidence for the presence of the Kennedy and Bremer-Greenberg pathways in the model organism Caenorhabditis elegans.
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