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Efficacy of trifluridine/tipiracil as IV line chemotherapy in a young woman with metastatic colorectal cancer. A case report

100%
Wiśniowski R.
OncoReview
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2020
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vol. 10
|
issue 1
23-26
EN
Colorectal cancer is the most common gastrointestinal malignancy and the third most frequently diagnosed cancer worldwide. Trifluridine/tipiracil represents an approved option for the treatment of advanced metastatic colorectal cancer in patients who are refractory, or are not considered candidates for currently available therapies. We present a case of a young woman with refractory metastatic colorectal cancer treated with this agent as the IV line of chemotherapy in which remarkable prolongation of progression free survival time was observed.
2
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Long-term disease control during TAS-102 therapy in the VI line treatment in a 73-year-old mCRC patient. A case report

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Skalij P., Tokajuk P., Jelski S., Wojtukiewicz M.
OncoReview
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2020
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vol. 10
|
issue 1
15-17
EN
A case of 73-year-old patient with metastatic colorectal cancer who underwent trifluridine/tipiracil therapy within the VI line was presented. Treatment with trifluridine/tipiracil allowed to achieve stabilization of the existing cancer for nearly 7 months.
3
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TAS-102 – a new option in the treatment of patients with advanced colorectal cancer after failure or intolerance to other therapies

100%
Skalij P., Tokajuk P., Wojtukiewicz M. Z.
OncoReview
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2020
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vol. 10
|
issue 1
8-14
EN
Colorectal cancer is the second cause of death from malignant cancer, following lung cancer. Approximately 35–45% of patients with colorectal cancer will develop distant metastases over time. Palliative systemic treatment remains the standard for non-operative distant metastases. TAS-102 is a novel orally administered antineoplasmatic thymidine-based nucleoside analog which represents an approved option for the treatment of advanced metastatic colorectal cancer in patients who are refractory, or are not considered canditates for, currently available therapies.
4
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Thrombosis of the deep dorsal penile vein and corpora cavernosa of the penis as the first symptoms of colon cancer. Case report and literature review

100%
Roslan M., Przudzik M., Borowik M., Wronka H., Kozielec Z., Michalak M., Grabysa R.
OncoReview
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2020
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vol. 10
|
issue 3
98-102
EN
The case describes an 86-year-old man with thrombosis of the deep dorsal vein and corpora cavernosa of the penis who developed symptoms 4 months before hospitalisation. An accurate imaging diagnostics supplemented with a biopsy of the corpus cavernosum confirmed the initial diagnosis. Moreover, an adenocarcinoma of the hepatic flexion of the colon with numerous metastatic lesions, including those to the crus of penis were found. Diagnostic and therapeutic difficulties were described and the results obtained were discussed in the context of available literature.
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