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An analysis of factor infl uencing the outcome of patients with locally advanced larynx cancer

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Kubrak J., Jarema A., Falco M., Rogowska D., Rubik A., Torbé B.
Otolaryngologia Polska
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2008
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vol. 62(6)
691-694
EN
Purpose. Results of treatment of locally advanced larynx cancer T3-4No-4 are unsatisfi ed. The aim of study is analysis of risk factors. Methods and Materials. 112 patiens with larynx cancer after radical surgical treatment had postoperative radiotherapy (conventional or accelarated). Results. The 3-year overall survival (OS) was 58%. Margin status and numer of risk factors had impast on OS. The 3-year locoregional control (LRC) was 80%. Number of risk factors, level of hemoglobin, overall tratment time and dose were signifi cantly associated with LRC. Incidence of distant metastases was asssociated with G3 suamous cell carcinoma and index of nalignancy H. Glanz.
2
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Accelerated postoperative radiotherapy in patients with advanced larynx cancer

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Kubrak J., Chosia M., Maj P., Jarema A.
Otolaryngologia Polska
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2010
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vol. 64(7)
60-64
EN
Aim: The aim of study was test effi cacy of accelerated postoperative radiotherapy – concomitant boost in patients with advanced larynx cancer. Methods and Materials: The prospective study included 112 patients with advanced larynx cancer after radical surgical treatment. Patients had postoperative radiation therapy, conventional (C) or accelerated (CB). Results: The 3-year overall survival in CB was 59%, in C – 58% (p=0,2), 3-year locoregional control in CB – 83%, in C – 75% (p=0.01), the 3-year disease free survival was in CB – 72%, C – 66% (p=0.1). Conclusion: Concomitant boost postoperative radition therapy did not improove overall survival, loco-regional control, disease free survival. Patients with close surgical margins, longer interval between surgery and radiation, high level of hemoglobin, T4 had benefi t from accelerated radiotherapy.
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Renesans of supracricoid partial laryngectomy with crico-epiglotto-hyoidopexy or with crico -hyoidopexy – is it possible? Literature rewiev

88%
Berger G., Kosztła - Hojna B., Reszeć J., Chyczewski L.
Polski Przegląd Otorynolaryngologiczny
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2017
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vol. 6(4)
14-23
EN
Supracricoid partial laryngectomy (SCPL) with crico-epiglotto-hyoidopexy (CHEP) or crico- hyoidopexy (CHP) is technically difficult. Although SCPL is effective in patients with laryngeal cancer, postoperative rehabilitation of speech and swallowing is needed for good functional outcomes. We discuss what patients can benefit from SCPL, with CHEP or CHP, and when these procedures are contraindicated.
4
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Phonosurgical voice rehabilitation in patients with primary larynx cancer after laser cordectomy CO2

88%
Berger G., Chyczewski L., Kosztyła-Hojna B.
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vol. 6(1)
48-57
EN
The aim of the treatment of early laryngeal cancer is complete oncological cure and simultaneously voice and swallowing preservation. According to the European Laryngological Society (ELS) classification of CO2 laser cordectomy, full voice recovery is seen in subepithelial cordectomy (ELS Type I ) and near complete in subligamental cordectomy (ELS type II). Voice deterioration is usually seen after more extensive levels of cordectomy (ELS types III-V). Voice quality after microsurgical laser cordectomy depends on the presence or absence of synechiae in the anterior commissure and on the quantity of the removed thyro-arytenoid muscle. More extensive reduction of the vocal muscle quantity causes more intensive glottic incompetence. Contralateral healthy vocal fold, rudimentary, cicatrixial previously operated vocal fold and false ventricular folds may take part in postoperative supraglottic voice compensation. All patients should undergo speech and voice therapy after terminating the scaring process on the operated vocal fold. Patients routinely undergo a minimum of 6 months of voice rehabilitation which allows speech therapy to yield the best possible voice. Phonosurgical techniques i.e. medialization thyroplasty, augmentation techniques, Zeitels’s laryngoplasty or Lichtenberger’s technique in treatment of synechia in the anterior commissure are successfully performed to restore the vocal competence. Voice preservation after treatment of early laryngeal cancer of the vocal fold improves life quality of the patient.
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