The aim of the present work is to present the problems connected with occupational therapy that make the major part of the programmes for the treatment for mobility limitations connected with different dysfunctions. In many cases, the obstacle in performing the comprehensive programme for the treatment for mobility is pain of a musculoskeletal character. This difficult problem is still connected with many questions and requires further research. In this paper some aspects of the problem are presented. Many occupational therapists, psychologists, physiotherapists, find the employment in this tough area of musculoskeletal pain is a very difficult challenging. Chronic pain has some features making occupational therapy difficult to conduct. An extensive review of the literature suggests that the knowledge around personalized medicine, rehabilitation and occupational therapy continues to grow.
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