Search results

1

Changes in the pancreas caused by different types of hypertension

100%

Nowińska P., Kasacka I.

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2017

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vol. 64

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issue 4

591-595

EN

Hypertension is considered a lifestyle disease. Unfavorable forecasts predict a significant increase in the number of patients suffering from this disorder. Many changes in various organs have been observed as a result of ischemia. An interesting question arises of whether differences between the mechanisms occurring in different types of hypertension could produce different effects in the organs. It is well known that there is a close relationship between hypertension and insulin resistance. On the other hand, insulin resistance is the main cause of type 2 diabetes, which develops in parallel with changes in the pancreas. The pancreas is a very important organ since it produces enzymes crucial for the digestive process, as well as performs an important endocrine function. The work presented here focuses primarily on the latter issue. The authors present an overview of contemporary literature concerning the influence of different types of hypertension on the function of the pancreas.

2

Comparison between bioelectrical impedance analysis and anthropometric indices in hypertensive patients

80%

Krzesiński P., Rozbicki P., Pałkowska-Goździk E., Banak M.

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vol. 14

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issue 3

301-305

EN

Aim: Obesity is one of the most crucial challenges of contemporary medicine. Bioelectrical impedance analysis is a useful tool to identify individuals with increased fat mass. However, the equipment is relatively expensive, especially compared to basic anthropometric methods. The aim of this study was to evaluate the relations between anthropometric indices and bioelectrical impedance analysis in patients with uncomplicated arterial hypertension. Material and methods: In 137 hypertensives the correlations between fat mass (absolute, FM; relative, %FM) and anthropometric parameters (body mass index, BMI; waist circumference, WC; waist-to-hip ratio, WHR; waist-to-height ratio, WHtR; body adiposity index, BAI; visceral adiposity index, VAI) were analysed. Results: Classic anthropometrics correlated well with bioimpedance indices of adipose tissue content: %FM vs. BAI (R = 0.77), WHtR (R = −0.54), BMI (R = 0.52), WC (R = 0.29); FM vs. BMI (R = 0.82), WC (R = 0.66), BAI (R = 0.58), VAI (R = 0.26), WHtR (R = 0.23), WHR (R = 0.19). In females BMI, WC and BAI showed the strongest correlations with adiposity. In males they were WHtR and WC. Conclusions: Some anthropometric measurements show good agreement with bioelectrical impedance analysis and can be considered a valid surrogate for body composition assessment in the case of its inaccessibility. In hypertensive women WC and BMI seem to be the most precise in the assessment of %FM, while in men WHtR and WC are more useful.

PL

Cel: Otyłość należy do głównych wyzwań współczesnej medycyny. Analiza bioimpedancyjna stanowi użyteczne narzędzie identyfikacji osób ze zwiększoną masą tkanki tłuszczowej. Niestety, sprzęt do analizy bioimpedancyjnej jest dość kosztowny, zwłaszcza w porównaniu z podstawowymi metodami antropometrycznymi. Celem pracy była ocena związku pomiędzy pomiarami antropometrycznymi a analizą bioimpedancyjną u pacjentów z niepowikłanym nadciśnieniem tętniczym. Materiał i metody: U 137 osób z nadciśnieniem tętniczym oceniono korelacje między ilością tkanki tłuszczowej (bezwzględnej, fat mass, FM; względnej, %FM) a parametrami antropometrycznymi (wskaźnik masy ciała, body mass index, BMI; obwód talii, waist circumference, WC; wskaźnik talia–biodra, waist-to-hip ratio, WHR; wskaźnik talia–wzrost, waistto-height ratio, WHtR; wskaźnik otłuszczenia ciała, body adiposity index, BAI; wskaźnik wisceralnej – trzewnej tkanki tłuszczowej, visceral adiposity index, VAI). Wyniki: Klasyczne pomiary antropometryczne korelowały z bioimpedancyjnymi wskaźnikami zawartości tkanki tłuszczowej: %FM vs BAI (R = 0,77), WHtR (R = −0,54), BMI (R = 0,52), WC (R = 0,29); FM vs BMI (R = 0,82), WC (R = 0,66), BAI (R = 0,58), VAI (R = 0,26), WHtR (R = 0,23), WHR (R = 0,19). U kobiet najsilniejszy związek z ilością tkanki tłuszczowej wykazywały BMI, WC i BAI, zaś u mężczyzn – WHtR i WC. Wnioski: Niektóre pomiary antropometryczne wykazują wysoką zgodność z analizą bioimpedancyjną i mogą być brane pod uwagę jako zastępcze wskaźniki oceny składu ciała w przypadku braku możliwości jej zastosowania. U kobiet z nadciśnieniem tętniczym najbardziej precyzyjne w ocenie %FM okazują się WC i BMI, podczas gdy u mężczyzn są to WHtR i WC.

3

Analysis of etiology and treatment methods of epistaxis in adult patients visiting

80%

Syniec M., Prygiel J., Dubielska A., Taradaj K., Deja M. D., Balcerzak J.

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2015

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vol. 4(4)

21-26

EN

Introduction: Epistaxis is not only the most commonly seen type of bleeding in laryngological emergency department, but also a frequent reason of visiting this department. It may be a symptom of trivial disorder or serious systemic either chronic disease.Aim of study: The primary objective of this study was to analyze the etiology and treatment methods of epistaxis in adult patients. Material and methods: This was the retrospective study of 574 adult patients who visited the Emergency Department of Otolaryngology in Public Central Teaching Hospital between 1st January and 30th December 2014 because of epistaxis. There were 274 females and 300 males with the mean age of 64,6 years (woman), and 60,3 years (men). Results: 228 patients (39,7%) were chronically treated for hypertension. Blood pressure measurement was performed in 335 patients (58,4%) and elevation over 160 mmHg systolic, or over 95mmHg diastolic took place in 132 cases (22,99%). Other significant factor observed in the study was anticoagulant and antithrombotic drug usage. In 134 cases (22,3%) patients were treated with medicine from this group (the most frequently- acetylsalicylic acid). Other accompanying disorders were: heart failure, atrial fibrillation, diabetes mellitus, other cardio-/cerebro-vascular diseases, COPD, respiratory track infection. The most common intervention in case of epistaxis was nasal packing (Rapid Rhino – 248 patients, Spongostan sponge – 129 patients). Captoprilum was administered in 79 cases (13,8%) to normalize elevated blood pressure. 90 patients (15,6%) required an additional internal medicine consultation. Conclusion: The impaired control of hypertension and treatment with oral anticoagulant (acenocumarol) or antithrombotic drugs (acetylsalicylic acid) were the most common reasons of epistaxis in examined group of patients. The most frequent symptomatic management were packing with Spongostan sponge and Rapid Rhino balloon tampon. Typical anterior nasal tamponade with gauze was much less frequent. The treatment according to the etiology was added if needed.

4

Acute Cardiovascular Alterations in Hypertensive Renal Patients During Exercise with Constant Load in the Interdialytic Period

80%

Malfatti C., Ferreira S.

Human Movement

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2010

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vol. 11

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issue 2

157-161

EN

Purpose. The study investigated acute cardiovascular alterations during aerobic exercise in interdialytic phase. Basic procedures. Seven hypertensive men with chronic renal disease (CRD) and seven healthy men (C) were matched according to the age (CRD: 48.5 ± 8.5; C: 45.28 ± 9.3) and body mass index (CRD: 24.2 ± 2.8 kgm-2; C: 26.7 ± 2.7 kgm-2). The exercise was executed on a cycloergometer during 6 minutes at 75% of HRmax and 3 minutes of recovery without load at 55 - 60 rpm. The patients came twice and were controlled only on an occasion at the hospital at 9.00 am. The exercise was performed before and 24 hours after haemodialysis (HD). The blood samples were drawn immediately before and 24 hours after HD for hematocrit and hemoglobin analysis. The statistical difference was verified by the ANOVA and two-tailed unpaired Student's t-test only for p < 0.05. Main findings. After HD, the systolic blood pressure (SBP) shows reduction in the first stage (~14%; p < 0.05) and in the recovery period of exercise (~18%; p < 0.05). A hypotension effect of HD was better observed in the diastolic blood pressure (DBP) from the 5th to 9th min of exercise (~20%; p < 0.05). The HD did not modify biochemical (hematocrit and hemoglobin), physiological (Rest SpO2; rest SBP; rest DBP and VO2max) and body weight parameters. Conclusions. The study showed a significant reduction in blood pressure levels during the exercise, principally in DBP 24 hours after HD, suggesting that exercise executed during this period can induce better tolerance to exercise in dialyzed patients.

5

Polymorphism in intron 23 of the endothelial nitric oxide synthase gene (NOS3) is not associated with hypertension.

80%

Derebecka N., Hołysz M., Dankowski R., Wierzchowski M., Trzeciak W. H.

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2002

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vol. 49

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issue 1

263-268

EN

Nitric oxide (NO) is synthesised in the vascular endothelium by nitric oxide synthase (NOS3) and is an important factor in the regulation of blood pressure. Impaired synthesis of NO due to mutations in the NOS3 gene is associated with hypertension. To date several allelic variants of the NOS3 gene have been identified and their possible linkage with hypertension investigated. We studied the distribution of genotypes and frequency of alleles of the G11T polymorphism in intron 23 of the NOS3 gene in patients with hypertension and in a control group of healthy individuals. The polymorphism was determined by PCR-RFLP analysis. The distribution of genotypes in the patients with hypertension and in the healthy individuals did not differ significantly from the values predicted from Hardy-Weinberg equilibrium for the general population. No major differences in the distribution of the G11T polymorphism in the patients and healthy individuals were found (P > 0.05).

6

The Prevalence of Arterial Hypertension among Students of West Pomeranian Voivodeship

80%

Umiastowska D., Żółtowska H.

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vol. 11

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issue 3

81-86

EN

The research was carried out as part of the research project N N 404 260335 “The lifestyle of children and adolescents and their level of athleticism, fitness and somatic development” during Crampton test in 2633 students of elementary, secondary and high schools in West Pomeranian Voivodeship. 214 subjects, that is 8.1% of the whole group, were qualified for the group with the hypertension. The arterial hypertension was reported in 7.9% of girls and 8.4% of boys. The statistically significant dependencies between the prevalence of arterial hypertension and the size of metropolitan area where the children and adolescents live, as well as their sex were observed.

7

White blood cells count and its populations in patients with acute coronary syndromes and co-morbidities

80%

Vakaliuk I., Alghzawi I.

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EN

INTRODUCTION: Acute coronary syndromes (ACS) and sudden death cause most ischemic heart disease (IHD)- related deaths, which represent 1.8 million deaths per year, with similar numbers of men and women dying from coronary artery disease (CAD). It’s known that inflammation plays crucial role in atherosclerotic plaque formation and its destabilization. The purpose of this study is to evaluate of white blood cells count in its subpopulation in patients with ACS and modifiable cardiovascular risk factors – arterial hypertension and 2 type Diabetes Mellitus (DM). MATERIAL AND METHODS: In this observational cohort trial we observed of 184 patients with ACS. All patients were randomized into four groups: 1st group - 42 patients with ACS without arterial hypertension (AH) or DM; 2nd group – 56 patients with ACS and previous AH; 3rd group – 42 patients with ACS and 2 type DM; and 4th group – 44 patients with ACS and AH and DM. We studied of leukocytes count and their subpopulations in blood. RESULTS: The mean white blood cells count was significant higher in patients with ASC, compared with control group: 8.23 [6.50; 9.40] vs 5.49 [5.20; 5.70] (p<0.001). Similarly, ACS caused increase of leukocytes subpopulation count in blood. The significant higher count of white blood cells was observed in patients with ACS and co-morbidities: 2 type DM and its association with AH. In patients with ACS and previous AH we observed significant lower neutrophils count (p<0.05), but increased quantity of lymphocytes, compared with patients with ACS without co-morbidities (p<0.001). DM and its association with AH was characterized of neutrophils, lymphocytes and monocytes counts growth. CONCLUSIONS:ACS is characterized of raised white blood cells count and its population, especially in cases of association with 2 type Diabetes Mellitus.

8

Phytotherapy as an alternative method to supp ort treatment of hypertension

80%

WYKURZ P., MUSZYŃSKA B.

Medicina Internacia Revuo

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2017

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vol. 28

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issue 108

202-215

EN

Hypertension is a dangerous chronic disease; it is the most common cause of death in Poland, Europe and the United States. In Poland, the estimated number of people with hypertension is about 36%. The development of this disease is progressive, a large proportion of people are unaware of their disease in the early stages. The use of basic recommendations for the prevention of hypertension i. e. stopping smoking, limiting alcohol intake and weight gain, increasing physical activity, limiting salt intake and changing eating habits can effectively lower blood pressure by 20-50 mm Hg. Such a considerable effect can significantly help a person with grade 2 hypertension (160-179 / 100-109 mm Hg). Phytotherapy is the branch of medicine that uses plants for medicinal purposes. Active compounds contained in plant raw materials can be used in heart and vascular diseases. They exhibit anti-arrhythmic, hypotensive, dilate peripheral, cerebral, coronary vessels, improving lipid profile, antioxidant, vasoprotective, antiplatelet, anti-inflammatory, immunostimulatory and diuretic. They exhibit negative chronotropic, but dromotropic and inotropic positive activity. Phytotherapy can be used as an alternative method to support the treatment of hypertension. In combination with basic preventive recommendations, it can delay the treatment by synthetic drugs for a very long time. It is therefore worth using herbs and their blends to improve the quality of our lives.

9

71%

Balbatun A., Louka F. R., Malinski T.

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2003

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vol. 50

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issue 1

61-68

EN

The endothelium plays a critical role in maintaining vascular tone by releasing nitric oxide (NO). Endothelium derived NO diffuses to smooth muscles, triggering their relaxation. The dynamic of NO production is a determining factor in signal transduction. The present studies were designed to elucidate dynamics of NO release from normal and dysfunctional endothelium. The nanosensors (diameter 100-300 nm) exhibiting a response time better than 100 μs and detection limit of 1.0×10-9 mol L-1 were used for in vitro monitoring of NO release from single endothelial cells from the iliac artery of normotensive (WKY) rats, hypertensive (SHR) rats, and normal and cholesterolemic rabbits. Also, the dynamics and distribution of NO in left ventricular wall of rabbit heart were measured. The rate of NO release was much higher (1200 ± 50 nmol L-1 s-1) for WKY than for SHR (460 ± 10 nmol L-1 s-1). Also, the peak NO concentration was about three times higher for WKY than SHR. Similar decrease in the dynamics of NO release was observed for cholesterolemic rabbits. The dynamics of NO release changed dramatically along the wall of rabbit aorta, being highest (0.86 ± 0.12 μmol L-1) for the ascending aorta, and lowest for the iliac aorta (0.48 ± 0.15 μmol L-1). The distribution of NO in the left ventricular wall of rabbit heart was not uniform and varied from 1.23 ± 0.20 μmol L-1 (center) to 0.90 ± 0.15 μmol L-1 (apex). Both, the maximal concentration and the dynamics of NO release can be useful diagnostic tools in estimating the level of endothelial dysfunction and cardiovascular system efficiency.

15

Increased Frequency of Ace Gene DD Genotype in Normotensive Male Smokers with Abdominal Aortic Aneurysm

71%

Waliszewski K., Słomski R., Oszkinis G., Majewski W., Pawlaczyk K.

Polish Journal of Surgery

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2007

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vol. 79

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issue 5

368-374

EN

The aim of the study was to assess whether the association between abdominal aortic aneurisms (AAAs) and the angiotensin-converting enzyme (ACE) DD genotype is changed in male smokers.Material and methods. The ACE I/D polymorphism was examined by PCR in 112 subjects with AAA and in 50 control subjects. The frequency of ACE genotypes (II, ID and DD) in the patient group was assessed in subgroups divided on the basis of blood pressure, smoking and sex.Results. A significant increase in the frequency of ACE DD genotypes has been found in all AAA patients studied (odds ratio OR=2.6; range 1.3-5.6, p <0.0002) when compared to the remaining ACE genotypes (ID and II) and the control group. The respective values were higher when all 74 male smokers with AAA were assessed (OR=3.6; p <0.006). No increase in ACE DD genotype frequency was seen in all females (38) and male nonsmokers when compared to the respective control group (n=16) (OR=1.4; p <0.75).In the group of normotensive AAA patients, the proportion of ACE DD genotype in relation to the remaining ACE genotypes (ID and II) was found to be higher than in the general AAA patient population (odds ratio OR=6.14; range 2.5-14.9, p <0.0001). In 32 normotensive male smokers with AAA, the respective values were higher (OR=8.3).Conclusions. An increased frequency of the ACE DD genotype in normotensive male smokers may account in large part for the increase in DD genotype occurrence noted in all AAA patients.

16

Risk factors for central serous chorioretinopathy

71%

Gawęcki M.

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issue 1

34-41

EN

Central serous chorioretinopathy is a well-described ocular disorder affecting primarily young individuals. As chronic forms of central serous chorioretinopathy are often leading to significant visual impairment, potential risk factors for its development are constantly analyzed in numerous studies. Review of available research shows that predominant risk factors for central serous chorioretinopathy include male gender, steroid intake, pregnancy, Cushing syndrome, chronic or acute stress, maladaptive personal traits, and increased choroidal thickness. Other factors, such as hypertension, gastric ulcer and reflux or genetic predispositions probably increase the risk of central serous chorioretinopathy onset, but its quantification remains the question of debate.

17

Ocena stężeń białka szoku termicznego Hsp60 u kobiet ciężarnych z nadciśnieniem tętniczym ciążowym w III trymestrze ciąży i po porodzie

61%

BODZEK P., STOŁTNY P., JANOSZ-GAŁDYŚ I., OLEJEK A.

Ginekologia i Położnictwo

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2014

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vol. 9

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issue 3

34-39

EN

Introduction. Heat shock protein (Hsp) in the human body provides protection against cellular and environmental stress factors. Their primary role is to weaken the effects of stressors. In conditions of cellular stress we observe the rapid increase in concentrations of Hsp in the cytoplasm and their transport, among others, to the nucleus, where it protects DNA, pre-mRNA, pre-ribosomes and nuclear proteins from degradation. Aim of the study. Evaluation of the clinical usefulness of the determination of the concentrations of heat shock protein Hsp60 in the following groups: healthy pregnant women, pregnant women with gestational hypertension in the third trimester of pregnancy and during labor and non-pregnant women. Material and methods. The study included 64 women: 28 pregnant women with pregnancy complicated by gestational hypertension, 16 healthy pregnant women and 20 healthy women who are not pregnant. The designation of the concentrations of heat shock proteins having a molecular weight of 60 kDa (Hsp60) was performed with use of enzyme-linked immunosorbent assay (ELISA). Results. Average concentrations of Hsp60 proteins were statistically significantly different between the start and end point of taking the sample for determination (III trimester of pregnancy vs. after delivery), both in the group of healthy pregnant women and in women with gestational hypertension. In both groups, the concentration of Hsp60 was significantly higher after delivery. In addition, a highly statistically significant difference in the concentration of Hsp60 between the group of non-pregnant women and healthy pregnant group after delivery was demonstrated, the concentration of Hsp60 was significantly higher after delivery. Conclusions. Pregnancy does not affect the concentration of the heat shock protein Hsp60. Delivery induces increased concentrations of heat shock proteins both in normal pregnancy and pregnancy complicated by hypertension.

PL

Wstęp. Białka szoku termicznego (Hsp) w organizmie człowieka pełnią funkcję ochronną przed czynnikami stresu komórkowego oraz środowiskowego. Podstawowa ich rola polega na osłabianiu efektów działania czynników stresowych W warunkach stresu komórkowego obserwowany jest szybki wzrost stężeń Hsp w cytoplazmie oraz ich transport m.in. do jadra komórkowego, gdzie chronił DNA, pre-mRNA, prerybosomy oraz białka jądrowe przed degradacją. Cel pracy. Ocena przydatności klinicznej oznaczania stężeń białek szoku cieplnego Hsp60 w grupach: zdrowych kobiet ciężarnych, ciężarnych z nadciśnieniem tętniczym ciążowym w III trymestrze ciąży i w okresie porodu oraz kobiet nieciężarnych. Materiał i metody. Badaniem objęto 64 kobiety: 28 kobiet ciężarnych z ciąż powikłaną nadciśnieniem tętniczym ciążowym, 16 zdrowych kobiet ciężarnych oraz 20 zdrowych kobiet nie będących w ciąży. Oznaczenia stężeń białek szoku cieplnego o masie cząsteczkowej 60 kDa (Hsp60) dokonano metodą immunoenzymatyczną (ELISA). Wyniki. Średnie stężenia białka Hsp60 różniło się znamiennie statystycznie pomiędzy początkowym i końcowym punktem pobrania (III trymestr ciąży vs. po rozwiązaniu ciąży) zarówno w grupie kobiet ciężarnych zdrowych, jak i w grupie kobiet z nadciśnieniem tętniczym ciążowym. W obu grupach stężenie Hsp60 było znamiennie wyższe po rozwiązaniu ciąży. Ponadto wykazano wysoce znamienną statystycznie różnicę w stężeniu Hsp60 pomiędzy grupą kobiet nieciężarnych a grupą ciężarnych zdrowych po rozwiązaniu ciąży, stężenie Hsp60 było znamiennie wyższe po rozwiązaniu ciąży. Wnioski. Ciąża nie wpływa na stężenie białka szoku termicznego Hsp60. Rozwiązanie ciąży indukuje wzrost stężenia białek szoku termicznego zarówno w ciąży fizjologicznej, jak i powikłanej ciążowym nadciśnieniem tętniczym.

18

The role of family support in self-control of individuals with hypertension in Sindangasih village, Cianjur regency

61%

Arini Ayu S., Sari Rahayu E., Eshadrianti Idris F.

Innowacje w Pielęgniarstwie i Naukach o Zdrowiu

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2023

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vol. 8

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issue 2

7-36

PL

Wstęp. Jeden z systemów wsparcia społecznego uzyskuje się od rodziny, członkowie rodziny odgrywają bardzo ważną rolę we wpływaniu lub zmianie własnego stylu życia w kierunku dążenia do poprawy zdrowia, w tym samoopieki osób z nadciśnieniem tętniczym. Cel. W badaniu tym zidentyfikowano rolę wsparcia rodziny dla samokontrolujących się osób z nadciśnieniem tętniczym w wiosce Sindangasih, Kab. Ciandżur. Metody badawcze. Projekt tego badania opiera się na analizie korelacji z przekrojem. Dobór próby metodą celowego doboru próby na łącznej próbie 106 osób. Dane Pierwotne uzyskane z kwestionariuszy i wyników obserwacji. Badania przeprowadzono w wiosce Sindangasih w okresie listopad 2022 – maj 2023. Wyniki. Wyniki testu statystycznego z wykorzystaniem ilościowych badań korelacyjnych o poziomie istotności (a) s0,05, wskazujące na istnienie związku pomiędzy rolą wsparcia emocjonalnego rodziny a zachowaniami samoopiekuńczymi osób z nadciśnieniem tętniczym (p=0,000), istnieje korelacja między rolą wsparcia poczucia własnej wartości rodziny a zachowaniami samoopiekuńczymi osób z nadciśnieniem tętniczym (p=0,001), istnieje korelacja między rolą wsparcia informacyjnego rodziny a zachowaniami samoopiekuńczymi osób z nadciśnieniem tętniczym (p =0,001), istnieje korelacja między rolą wsparcia instrumentalnego rodziny a zachowaniami samoopiekuńczymi osób z nadciśnieniem tętniczym (p=0,000), istnieje korelacja między rolą wsparcia rodziny a zachowaniami samoopiekuńczymi osób z nadciśnieniem tętniczym (p=0,000) w wiosce Sindangasih, Kab. Ciandżur. Wnioski. Wsparcie rodziny może być strategią, którą można zastosować w leczeniu nadciśnienia tętniczego i innych chorób, ponieważ jest ono uwzględnione w obu przypadkach i ma pozytywny wpływ na nawyki samoopieki pacjenta.

EN

Introduction. One of the social support systems is obtained from the family, family members play a very important role in influencing or changing their own lifestyle towards efforts to improve health including self-care for people with hypertension. Aim. This study identified the role of family support on self-control individuals with hypertension in Sindangasih Village, Kab. Cianjur. Research Methods. The design of this study is correlation analytic with the cross-sectional. Sampling using purposive sampling with a total sample of 106 people. Data Primary obtained from questionnaires and observation results. The research was conducted in the village Sindangasih with a timeframe of November 2022 - May 2023. Results. The results of the statistical test using quantitative correlation research with a significance level (a) s0.05, indicating that there is a correlation between the role of family emotional support and the self-care behavior of people with hypertension (p=0.000), there is a correlation between the role of family esteem support and the self-care behavior of people with hypertension (p=0.001), there is a correlation between the role of family information support and the self-care behavior of people with hypertension (p=0.001), there is a correlation between the role of family instrumental support and the self-care behavior of people with hypertension (p=0.000), there is a correlation between the role of family support and self-care behavior of hypertension sufferers (p=0.000) in Sindangasih Village, Kab. Cianjur. Conclusion. Family support can be a strategy that can be used to manage hypertension and other diseases because it is included in both and positive impact on patient self-care habits.

19

Cost-effectiveness analysis of psychotherapy in treatment of essential hypertension in primary care

61%

Kalmatayeva Z., Zholamanova A.

Archives of Psychiatry and Psychotherapy

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2014

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vol. 16

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issue 4

57-64

EN

Aim of the study. To estimate expediency of psychotherapy in patients with essential hypertension from a clinical and economic perspective. Place and duration of study. Clinical material was collected from September 2011 to February 2012 in Polyclinic no. 12, Almaty and the Central City’s Polyclinic, Kaskelen. Method. 75 patients with identified psychosomatic disorders (37 male, 38 female) suffering from hypertension of a first or second degree (from 140/90 to 179/109mmHg) were randomised into two groups (mean age 48.5±3.69 and 47.5±4.2 years). All patients received therapy within the same scheme, but group 1 was additionally treated with psychotherapy. Results. Qualitative improvements were shown on all scales of the “Mini-mult” test for group 1. The control examination of mean blood pressure (BP) at week 14 found a statistically significant difference in final systolic blood pressure (SBP) between the two groups (134.27±3.7 vs. 137.33±3.9, p=0.032), but no such difference in final diastolic blood pressure (DBP) (82.93±5.1 vs. 83.81±4.3, p=0.198). The average cost of the 24-week treatment per person was 47.81USD for group 1 (standard treatment with psychotherapy) and 48.62USD for group 2 (standard treatment). The cost of SBP reduction was 1.98 vs. 2.53USD per 1mmHg for group 1 and 2 respectively and for DBP reduction it was 3.19 vs. 3.73USD per 1mmHg for group 1 and 2 respectively. Blood pressure (BP) reduction was faster in group 1 (7.05 vs. 7.97 weeks). Conclusions. Conservative treatment of hypertension combined with comprehensive psychotherapy leads to better results compared with a conventional conservative treatment scheme, from psychological, clinical and economic points of view, bur results can be different in another country. More trials in different countries with greater numbers of patients are necessary.

20

Czy występują istotne różnice w ilości zażywanych leków przeciwnadciśnieniowych między chorymi na cukrzycę i nadciśnienie tętnicze a chorymi na nadciśnienie tętnicze?

61%

Markowicz A., Grzeszczak W.

Annales Academiae Medicae Silesiensis

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2018

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issue 72

209-215

EN

INTRODUCTION: Diabetes, as well as hypertension, cause significant deterioration in the quality of life as well as shortening the patient’s survival time. The aim of the study was to find answers to the following questions: 1) how many antihypertensive drugs are used by patients with hypertension and by patients with diabetes and hypertension; 2) are more antihypertensive drugs used by patients with impaired renal function; 3) are there any differences in the amount of antihypertensive drugs used between the observed groups. MATERIAL AND METHODS: The study included 300 consecutive patients qualified for urgent admission to the Department of Internal Medicine, Diabetology and Nephrology in Zabrze. The reason for admission was unstable blood pressure in subjects with hypertension and diabetes or hypertension without diabetes. Body weight and height were measured using an AED mechanical column scale. 24-hour automatic blood pressure measurement was performed with an Oscar 2 device. RESULTS: There were no statistically significant differences between the amount of medication used by patients with hypertension with or without diabetes. It was shown that along with deteriorating kidney function, the subjects used significantly more antihypertensive drugs (especially diabetic patients and those with hypertension). CONCLUSIONS: 1. Patients with hypertension and with or without diabetes use on average 3.53 ± 2.22 antihypertensive drugs. In this regard, differences between the studied groups were not demonstrated. 2. Along with deteriorating kidney function, the number of antihypertensive drugs used by patients increases, especially in patients with diabetes. 3. Along with deteriorating kidney function, the amount of antihypertensive medication used is higher in patients with diabetes and hypertension compared to hypertensive patients without diabetes.

PL

WSTĘP: Cukrzyca oraz nadciśnienie tętnicze powodują zarówno istotne pogorszenie jakości życia, jak i skrócenie czasu przeżycia chorego. Celem pracy było znalezienie odpowiedzi na następujące pytania: 1) ile średnio leków przeciwnadciśnieniowych zażywa chory na nadciśnienie oraz chory na cukrzycę i nadciśnienie tętnicze; 2) czy na skutek upośledzenia czynności nerek chorzy zażywają większą ilość leków przeciwnadciśnieniowych; 3) czy występują różnice w ilości stosowanych leków przeciwnadciśnieniowych między badanymi przez nas grupami. MATERIAŁ I METODY: Do badania włączyliśmy kolejnych 300 chorych zakwalifikowanych w trybie pilnym do przyjęcia do Kliniki Chorób Wewnętrznych, Diabetologii i Nefrologii w Zabrzu. Powodem przyjęcia były nadciśnienie tętnicze i cukrzyca lub nadciśnienie tętnicze bez cukrzycy. Pomiaru masy ciała oraz wzrostu dokonano przy użyciu mechanicznej wagi lekarskiej kolumnowej ze wzrostomierzem firmy AED. 24-godzinnego automatycznego pomiaru ciśnienia tętniczego krwi dokonano aparatem Oscar 2. WYNIKI: Nie wykazano znamiennych statystycznie różnic między ilością stosowanych leków u chorych na nadciśnienie z cukrzycą lub bez cukrzycy. Wykazano, że wraz z pogarszającą się czynnością nerek badani zażywali istotnie więcej leków przeciwnadciśnieniowych (szczególnie chorzy na cukrzycę i nadciśnienie tętnicze). WNIOSKI: 1. Chorzy na cukrzycę i nadciśnienie tętnicze oraz chorzy na nadciśnienie tętnicze bez cukrzycy stosują średnio 3,53 ± 2,22 leków spośród określonych grup leków przeciwnadciśnieniowych. Brak różnic w ilości zażywanych leków między badanymi grupami. 2. Wraz z pogorszeniem czynności wydalniczej nerek wzrasta ilość leków przeciwnadciśnieniowych zażywanych przez chorych, szczególnie u chorych na cukrzycę. 3. Wraz z pogorszeniem czynności nerek ilość stosowanych leków przeciwnadciśnieniowych jest większa u chorych na cukrzycę i nadciśnienie niż u chorych na nadciśnienie bez cukrzycy.

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