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  1. 2 OncoReview

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  1. 2 2017

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  1. 2 Kuc-Rajca M.

  2. 2 Walaszkowska-Czyż A.

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Lapatinib in the treatment of advanced HER2-positive breast cancer

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Kuc-Rajca M., Walaszkowska-Czyż A.
OncoReview
|
2017
|
vol. 7
|
issue 3
144-149
EN
The overexpression of the HER2 receptor and its gene amplification are observed in c. 20% of newly diagnosed cases of breast cancer and associated with a more aggressive clinical course and poorer prognosis. New HER2-targeted drugs, such as lapatinib, pertuzumab and trastuzumab emtansine, significantly improve patient outcomes. The article reviews the role of lapatinib in HER-targeted therapy and describes the treatment sequence of two women with HER2-positive advanced breast cancer.
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Publication available in full text mode
Content available

Lapatinib in the treatment of advanced HER2-positive breast cancer

100%
Kuc-Rajca M., Walaszkowska-Czyż A.
OncoReview
|
2017
|
vol. 7
|
issue 3
144-149
EN
The overexpression of the HER2 receptor and its gene amplification are observed in c. 20% of newly diagnosed cases of breast cancer and associated with a more aggressive clinical course and poorer prognosis. New HER2-targeted drugs, such as lapatinib, pertuzumab and trastuzumab emtansine, significantly improve patient outcomes. The article reviews the role of lapatinib in HER-targeted therapy and describes the treatment sequence of two women with HER2-positive advanced breast cancer.
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