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1
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The role of pepsin in the laryngopharyngeal reflux

100%
Kowalik K., Krzeski A.
Otolaryngologia Polska
|
2017
|
vol. 71(6)
7-13
EN
Laryngopharyngeal reflux (LPR) is a common defect among laryngological and phoniatric patients. Although LPR is categorized as a superficial gastroesophageal reflux disease (GERD), differential diagnosis should treat these two diseases separately. LPR symptoms can be assessed in the interview using as a tool the reflux symptom index (RSI). In addition, changes in the larynx that occur during LPR might be seen during laryngoscopy and classified according to the reflux finding score (RFS). One of the main mucosal irritants in LPR is pepsin which digests proteins and impairs the functions of the upper respiratory tract cells by affecting carbonate anhydrase (CAIII) and the Sep 70 protein. Pepsin initiates inflammatory changes within the larynx, nasopharynx and nasal cavity. The use of pepsin detection in upper and lower throat secretions is a new direction in LPR diagnostics.
2
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Laryngeal tumour of neurogenetic origin – case report and review of the literature

100%
Majszyk D., Krawczyk P., Kloc M., Rytel A., Osuch-Wójcikiewicz E., Niemczyk K.
Polski Przegląd Otorynolaryngologiczny
|
2019
|
vol. 8(3)
35-39
EN
Schwann cell tumours are a rare group of benign neoplasms that origin form peripheral nerves. 0.1%–1.5% develops in the larynx causing hoarseness, difficulty swallowing and dyspnoea. The treatment of choice is surgical resection of the tumour during open type surgery or endoscopic procedure. The chosen surgical technique depends on tumour location, size observed in clinical examination and imaging. Also, clinical manifestation of the disease is included in the decision-making process.
3
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The role of pepsin in the laryngopharyngeal reflux

100%
Kowalik K., Krzeski A.
Polish Journal of Otolaryngology
|
2017
|
vol. 71
|
issue 6
7-13
EN
Laryngopharyngeal reflux (LPR) is a common defect among laryngological and phoniatric patients. Although LPR is categorized as a superficial gastroesophageal reflux disease (GERD), differential diagnosis should treat these two diseases separately. LPR symptoms can be assessed in the interview using as a tool the reflux symptom index (RSI). In addition, changes in the larynx that occur during LPR might be seen during laryngoscopy and classified according to the reflux finding score (RFS). One of the main mucosal irritants in LPR is pepsin which digests proteins and impairs the functions of the upper respiratory tract cells by affecting carbonate anhydrase (CAIII) and the Sep 70 protein. Pepsin initiates inflammatory changes within the larynx, nasopharynx and nasal cavity. The use of pepsin detection in upper and lower throat secretions is a new direction in LPR diagnostics.
4
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Oncocytic cystadenoma of the larynx – case report

100%
Czesak M., Bruzgielewicz A., Niemczyk K.
|
2015
|
vol. 4(4)
45-48
EN
An uncommon oncocytic cystadenoma of the larynx in a 60-year-old woman is presented. The only one symptom reported by the patient was hoarseness. She was treated by endolaryngeal surgery with CO2 laser excision. Pathogenesis and methods of treatment are discussed.
5
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Role of psychological factors in pathogenesis of disturbances of voice caused with vocal nodules

88%
Ratajczak J., Grzywacz K., Wojdas A., Rapiejko P., Jurkiewicz D.
Otolaryngologia Polska
|
2008
|
vol. 62(6)
758-763
EN
Introduction. Hoarseness is most frequent complaint notifi ed by ill in phoniatric outpatient clinics. Looking of causes notifi ed of disturbances of voice often we ascertain in larynx existence of vocal nodules. Changes these come into being in consequence of excessive or irregular phonations. Single incident of disturbances of voice caused with oedema changes nascent of in consequence of inappropriate work with voice does not wake of our trouble, instead returns this of type of complaint provoke to other researches coexisting of etiological factors this diseases. Aim. Estimation of infl uence of individual personality trait of ill on formation of vocal nodules. Material and methods. One examined 20 patients with vocal nodules classifi ed to treatments operating and 20 without disturbances of voice. All patients were subjected to otolaryngological and stroboscopic examinations. Character created of voice one examined at help of scale GRBAS, instead infl uence of disturbances of voice on quality of life ill at help of test VHI. Psychological examinations one executed using questionnaire State-Trait-Anxiety-Inventory( STAI), questionnaire NEO-FFI and questionnaire of aggression Buss-Perry. Results. Obtained results showed, that persons with returning vocal nodules, both during of research as in different situations everyday lives characterizes with higher level of fear and have greater inclination to worry oneself. Ill from groups examined in greater degree are extroverts, show greater activity and more are contagious socially in comparison to persons of comparative group. Attitude this in situations extorting rivalry will be able to be ruthless, are well organized guided, scrupulous and consistently endeavour to aim. Conclusions. Wanting effi ciently to treat persons with returning vocal nodules we should subject to ill psychological examination and in once of ascertainment of irregularity to correct it, what at simultaneous correct treatment of organic changes should diminish frequency or to eliminate returns of disease. Skill psychological looks on patient by therapists treating disturbances of voice and speeches in case not large emotional instabilities probably would be able to improve results of treatment ill not only with functional disturbances of voice but also with disturbances of voice caused with organic changes in larynx.
6
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Recurrent hypertrophic laryngeal lesions in a patient with a history of pesticide exposure – a case report

88%
Kloc M., Krawczyk P., Rzepakowska A., Niemczyk K.
Polski Przegląd Otorynolaryngologiczny
|
2020
|
vol. 9(1)
39-44
EN
Chronic irritation of the laryngeal mucosa by external factors can lead to the development of dysphonia: hoarseness, change of the voice tone or weakening of its strength. Patients who additionally report alarming symptoms, such as dyspnea, dysphagia, or odynophagia require urgent diagnosis and treatment. Long-term exposure to irritants may lead to the development of numerous recurrent hypertrophic laryngeal lesions requiring continuous otorhinolaryngological care and multiple surgical procedures, as it was in the presented case.
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