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The effects of cochleostomy of hearing threshold in animal experiment

100%
Stanisławek-Sut O., Morawski K., Niemczyk K.
Otolaryngologia Polska
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2010
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vol. 64(7)
17-21
EN
SUMMARY Introduction: To assess an effect of cochleostomy on hearing threshold in guinea pigs. Material and methods: The authors performed animal experiments using fi ve 3-month-old guinea pigs. Before experiment hearing threshold were evaluated. Surgery involved access to the temporal bone by a post-auricular incision. After a wide opening of the bulla cochleostomy was created (10 000 turn/min, diamond bur of 0,8 mm diameter). Hearing threshold was identifi ed on the basis of presence of wave V in auditory brainstem responses (ABR) for click and frequency-specifi c stimulation. Also morphology and latency changes for wave V for this stimulation was assesed. Hearing status was evaluated before, just after and 1-, 2-, and 4-weeks after surgery. For surgical procedure and ABR examination all animals were anesthetized with an intramuscular injection of ketamine (50 mg/kg) mixed with xylazine (9 mg/kg) in the supplemental doses. After surgery the animal was treated by antibioticoterapy for 3 days – Enrofl oksacyna 0,3 ml subcutaneouly and analgesic – Tolfedine 0,05 mg in second day. Results: Four week observation of ABR morphology and hearing thresholds for click and frequency-specifi c stimulation of 100 dB SPL intensity showed only temporary changes confi rming that cochleostomy did not affect cochlear function. Conclusions: The correctly performed cochleostomy in guinea pigs did not affect persistently the cochlear function indicating that such an option of CI electrode insertion in patients is safe.
2
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Stability of ABR Wave V Threshold in Early Hearing Diagnostics in Children from Selected Groups at Risk of Congenital Hearing Loss

100%
Kocoń S., Skórkiewicz K., Stręk P., Ziarno R., Składzień J., Hartwich P., Tomik J.
Polish Journal of Otolaryngology
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2021
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vol. 75
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issue 1
7-15
EN
Introduction: Upon hearing that the “little” patient has trouble with hearing, we are mostly interested in the level of his hearing threshold. When the child is in the first year of life, results can only be achieved by means of ABR test. Subsequent control tests, especially in children from the hearing loss risk groups selected in this study, show that the obtained outcomes are subject to fluctuations. Their fluctuating nature is manifested by the instability of wave V threshold in subsequent diagnostic periods. Such variability often delays the implementation of the appropriate proceeding. Knowledge of the dissimilarity of behavior of the wave V threshold occurring in individual groups at risk of hearing loss allows for the correct interpretation of the obtained results, and thus, effective therapeutic measures. Aim: The aim of the paper is to analyze the stability of wave V threshold during the first year of life in children from selected risk groups for congenital hearing disorders. Material and methods: From the patient population of 2,114 individuals examined in 2015–2016 at a reference center participating in the Universal Neonatal Hearing Screening Program in 2015–2016, the results of 250 children were subjected to retrospective analysis. Furthermore, 4 groups of little patients were formed (children with Down syndrome; children with other diseases or damage to the nervous system; children with cleft palate or cleft lip and cleft palate; children with congenital cytomegaly) in whom diagnostic practice revealed variable results of the wave V threshold. We analyzed the results of tests obtained during the first year of the child’s life divided into 4 diagnostic periods. Results: The highest percentage of instability in the established threshold of wave V between individual diagnostic periods occurred in the group of children with cleft palate or cleft lip and cleft palate. In the group of children with Down syndrome, it was observed that the instability of the ABR test results decreased over time. In the group of children with other diseases or damage of the nervous system, the highest percentage of the lack of stable ABR wave V thresholds was observed between the 1st and 2nd as well the 1st and 4th diagnostic periods. On the other hand, in the group of children with congenital CMV, there was a relatively low percentage of instability of results. Conclusions: (1) Although the ABR test is a diagnostic standard, in particular groups of patients the study is burdened with high variability of measurement results in subsequent diagnostic periods. Such a group of patients are children with cleft palate or cleft lip and cleft palate; therefore, it must receive particular attention in treatment planning; (2) in selected groups at risk of hearing loss, due to the high percentage of children with hearing impairment (70%), the validity of performing newborn hearing screening tests was confirmed.
3
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Preliminary Study on the Influence of Headphones for Listening Music on Hearing Loss of Young People

100%
Dobrucki A. B., Kin M. J., Kruk B.
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4
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The estimation of behavioral audiograms, auditory brainstem response (ABR) thresholds and auditory steady-state response (ASSR) thresholds of young adults with normal hearing

100%
Szymańska A., Gryczyński M., Pajor A.
Otolaryngologia Polska
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2008
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vol. 62(6)
735-739
EN
Introduction. One of the basic audiological parameter in estimation of hearing sensitivity is hearing threshold. The need for an objective tool to effi ciently predict the audiogram caused that the use and importance of ASSR method is growing in recent times. However, the technique is quite new and needs to be still improved. Aim of the study was the estimation of behavioral audiogram in comparison with ABR and ASSR threshold of young adults with normal hearing. Material and methods. The study sample included 9 subjects with normal hearing (18 ears) with no abnormalities in otoscopy. Behavioral hearing thresholds and ASSRs to carrier frequencies of 0.5, 1, 2, and 4 kHz were obtained. The ASSRs were assessed with Bio-logic MASTER system by the use of four sinusoidal tones both frequency – and amplitude – modulated given simultaneously to every ear for each carrier frequency. The potentials are collected, averaged and analyzed in this method by the fast Fourier transform to yield statistically signifi cant responses. Electrophysiologic threshold responses for click ABR stimuli for the same carrier frequencies for right and left ear were obtained by the use of Bio-logic Navigator Pro unit. Differences and correlations between the ASSRs, ABRs and the behavioral thresholds were determined. Results. We discovered that the values of pure tone audiograms and ABRs thresholds values differ from ASSRs considerably. We could also observed that the difference between behavioral and ABRs threshold is less than for behavioral and ASSRs threshold. Conclusion. To conclude, this study shows that auditory steady-state responses technique is not useful method in estimating of hearing threshold of young adults with normal hearing.
5
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Stability of ABR Wave V Threshold in Early Hearing Diagnostics in Children from Selected Groups at Risk of Congenital Hearing Loss

100%
Kocoń S., Skórkiewicz K., Stręk P., Ziarno R., Składzień J., Hartwich P., Tomik J.
|
|
vol. 75(1)
7-15
EN
Introduction: Upon hearing that the “little” patient has trouble with hearing, we are mostly interested in the level of his hearing threshold. When the child is in the first year of life, results can only be achieved by means of ABR test. Subsequent control tests, especially in children from the hearing loss risk groups selected in this study, show that the obtained outcomes are subject to fluctuations. Their fluctuating nature is manifested by the instability of wave V threshold in subsequent diagnostic periods. Such variability often delays the implementation of the appropriate proceeding. Knowledge of the dissimilarity of behavior of the wave V threshold occurring in individual groups at risk of hearing loss allows for the correct interpretation of the obtained results, and thus, effective therapeutic measures. Aim: The aim of the paper is to analyze the stability of wave V threshold during the first year of life in children from selected risk groups for congenital hearing disorders. Material and methods: From the patient population of 2,114 individuals examined in 2015–2016 at a reference center participating in the Universal Neonatal Hearing Screening Program in 2015–2016, the results of 250 children were subjected to retrospective analysis. Furthermore, 4 groups of little patients were formed (children with Down syndrome; children with other diseases or damage to the nervous system; children with cleft palate or cleft lip and cleft palate; children with congenital cytomegaly) in whom diagnostic practice revealed variable results of the wave V threshold. We analyzed the results of tests obtained during the first year of the child’s life divided into 4 diagnostic periods. Results: The highest percentage of instability in the established threshold of wave V between individual diagnostic periods occurred in the group of children with cleft palate or cleft lip and cleft palate. In the group of children with Down syndrome, it was observed that the instability of the ABR test results decreased over time. In the group of children with other diseases or damage of the nervous system, the highest percentage of the lack of stable ABR wave V thresholds was observed between the 1st and 2nd as well the 1st and 4th diagnostic periods. On the other hand, in the group of children with congenital CMV, there was a relatively low percentage of instability of results. Conclusions: (1) Although the ABR test is a diagnostic standard, in particular groups of patients the study is burdened with high variability of measurement results in subsequent diagnostic periods. Such a group of patients are children with cleft palate or cleft lip and cleft palate; therefore, it must receive particular attention in treatment planning; (2) in selected groups at risk of hearing loss, due to the high percentage of children with hearing impairment (70%), the validity of performing newborn hearing screening tests was confirmed.
6
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The Influence of a Single Therapeutic Dose of Methadone on Selected Auditory Functions in Patients Addicted to Opioids and Undergoing Substitution Therapy – a Preliminary Study

75%
Tarnowska E., Wicher A., Sęk A., Gorzelańczyk E. J.
Archives of Acoustics
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2018
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vol. 43
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issue 1
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