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EN
The aim of the paper is to present an overview of recent findings on the environmental and behavioral factors influencing the development of atherosclerosis. The authors primarily concentrated on deliberations of possibile main causes of the damage of the endothelium. At the same time the following pathogenic mechanisms as cellular dysfunction, inflammation and coagulation disorders have been enumerated. The links between the state of the vascular endothelium and life style have been emphasized. It is also important to note that the primary causes of the endothelial damage should be traced as originally suggested many years ago viewing such factors as anger, hostility, aggression, impulsiveness and depression but with a new approach. The authors supplement the comments, on the environmental factors influencing the development of atherosclerosis, with basic data on family predisposition to the development of this disease. They highlight that current genetic research have not determined genes responsible for atheroscelosis. According to the authors the considerations and conclusions presented in this overview are important for the educational purposes related to the most frequent disease process resulting in many diseases in medical disciplines.
PL
Celem pracy jest dokonanie przeglądu najnowszych ustaleń dotyczących czynników środowiskowych i behawioralnych biorących udział w powstawaniu i patogenezie miażdżycy. Tym samym, jakkolwiek wymieniono w niej takie mechanizmy patogenetyczne jak zaburzenia funkcji makrofagów, procesy zapalne i zaburzenia krzepnięcia, to jednak autorzy skoncentrowali się przede wszystkim na rozważeniu możliwych pierwotnych przyczyn uszkodzenia śródbłonka naczyń. Podkreślono powiązania pomiędzy jego stanem a stylem życia. Istotnym jest zwrócenie uwagi na fakt, że poszukując pierwotnych przyczyn uszkodzenia śródbłonka należy ponownie – lecz z użyciem nowego warsztatu – rozważyć rolę zaproponowanych, już wiele lat temu, czynników osobowościowych i behawioralnych, a wśród nich wrogość, agresywność, impulsywność czy depresję. Komentarze o środowiskowych czynnikach wpływających na rozwój miażdżycy uzupełniono ponadto danymi na temat predyspozycji rodzinnej do powstawania tego procesu chorobowego. Podkreślono, że dotychczasowe badania genetyczne nie określiły krytycznych chorobotwórczych wariantów genów, co skłoniło autorów do tymczasowego sformułowania o „braku wyznaczników dziedziczności”. Przedstawione rozważania mają zdaniem autorów znaczenie dla uzupełnienia procesu dydaktycznego dotyczącego tego najbardziej rozpowszechnionego procesu chorobowego skutkującego licznymi jednostkami chorobowymi w wielu dyscyplinach medycznych.
EN
Clefts that occur in children are a special topic. Avoiding risk factors, and also an early diagnosis of cleft possibility can result in minimizing or avoiding them. If on the other hand when clefts occur they require a long-term, multistage specialized treatment. Etiology of clefts seems to be related to many factors. Factors such as genetic, environmental, geographic and even race factors are important. Identification of risk factors can lead to prevention and prophylactic behaviors in order to minimize its occurrence. Exposure to environmental factors at home and work that lead to cleft predisposition should not be disregarded. It seems that before planning a family it would be wise to consult with doctors of different specializations, especially in high-risk families with cleft history in order to analyze previous lifestyle. Clefts are very common in hereditary facial malformations and are causing a lot of other irregularities in the head and neck region. In this paper after a brief papers review authors present socio-geographic, environmental and also work place related factors that are influencing pregnant women condition and should be taken under serious consideration.
EN
The purpose of the study was to assess factors determining physical activity in persons at the age of 60-69 years in an urban area. The study included 262 working residents of Warsaw at the initial period of old age. The study utilized a questionnaire consisting of two parts. The first part concerned recreational and touristic activities in the previous year. The second is a Polish version of IPAQ, assessing the respondents' level of activity throughout the past week. Based on IPAQ results, the respondents were divided into physically active and inactive ones. The active group included people meeting moderate to vigorous physical activity, whereas the inactive group included people who took up no physical activity at all or those with a low physical activity level. The relations between taking up physical activity and the variables characterizing the demographic structure as well as touristic and recreational activity of the respondents were assessed with the use of a log-linear analysis. Out of the variables taken into account, age, education and participation in physical recreation proved to be significant factors in taking up activity by the elderly. The odds ratios computed for the analyzed variables indicate that the risk of being inactive increases over two times after exceeding 65 years of age; a risk of similar magnitude was also observed in case of less educated populations. Regular participation in physical recreation provides a four-times increase in the chances to achieve levels of physical activity sufficient to remain healthy.
EN
Dyslexia is the most common learning disability in school and the most devastating in terms of academic performance. In interaction with the socio-cultural environment, several and various factors can aggravate the difficulties of reader acquisition in dyslexic children. Identifying these factors and interpreting them according to the neuropsychological approach, in the Moroccan context, was the objective of this study Socio-economic data was collected from 626 children, aged 9 to 15 years with an average age of 11,95 years, enrolled in public educational establishments in the Beni Mellal-Khenifra region, located in central Mo- rocco. Among all the participants, 41 had a profile of dyslexia, 13 of whom had reading attitudes evoking "severe dyslexia". Subjects underwent a cognitive assessment. the others were normal-readers and classified as good readers (n=481) and weak readers (n=104). To follow our purpose, we have determined socio-cultural and cognitive variables that may discriminate between students in the "severely dyslexic" group and their "dyslexic" peers. The performance gap was significant in favor of "dyslexic" students in the reading test of pseudowords, rapid naming of images, and the deletion of the initial phoneme. These data reinforce the hypothesis that the phonological deficit is at the root of developmental dyslexia. On the socio-cultural domain, the results showed that preschool attendance and early exposure to written language activity discriminate the participants with a "severe dyslexia" profile from their peers in the "dyslexic" group. We believe that these two factors were responsible for the moderate intensity of the disorder observed in the "dyslexic" group. Our study also showed that bilingualism raises the degree of learning reading difficulties among students with this disorder. These results are consistent with those described in the literature, it suggests that dyslexics can implement compensation strategies both at the behavioral and neuronal level. They call on those in charge of the Moroccan education system to recognize the existence of learning disabilities of neurobiological origin in order to address the necessary care for children who suffer from them.
EN
Admission. Diabetes mellitus is a chronic metabolic disease resulting from disturbed secretion or action of insulin, a hormone produced by the pancreas. It is genetically and multigene conditioned and by environmental factors, mainly obesity, bad eating habits and lack of physical activity. Aim. The aim of this study was to assess the influence of genetic conditions and environmental factors on the incidence of type 2 diabetes. Material and methods. In this work, the survey technique and classic qualitative analysis of documents were used. Research tools are used for the technical collection of data, such as: interview questionnaire, observation sheet, dictaphone, pen, etc. Patients from the CDL Barska Diabetes Clinic in Włocławek participated in the study. The condition was the patient's written consent. Patients received the questionnaire and it was conducted with their consent Results. One of the factors causing complications is alcohol consumption. Most respondents stated that they do not consume alcohol (45%), but a very large proportion of the respondents admitted that they drink alcohol occasionally (44%). Patients indicated that alcohol may induce hypoglycaemia (51%). Most of the respondents answered that alcohol is bad for the treatment of type 2 diabetes (88%). When indicating the type of physical activity, the respondents most often reported walking (48,4%) and cycling (25,8%). Patients admitted that they do physical activity once a week (34%) or not at all (27%). Conclusions. Genetic and environmental factors in the incidence of type 2 diabetes are playing the very important role.
PL
Wstęp. Cukrzyca jest przewlekłą chorobą metaboliczną wynikająca z zaburzonego wydzielania lub działania insuliny – hormonu produkowanego przez trzustkę. Jest ona uwarunkowana genetycznie-wielogenowo oraz poprzez czynniki środowiskowe, głównie otyłość, złe nawyki żywieniowe oraz brak aktywności fizycznej. Cel. Celem niniejszej pracy była ocena wpływu uwarunkowań genetycznych i czynników środowiskowych na zachorowalność na cukrzycę typu 2. Materiał i metody. W niniejszej pracy wykorzystano technikę ankietowania oraz klasyczną jakościową analizę dokumentów. Narzędzia badawcze służą technicznemu gromadzeniu danych i są nimi np.: kwestionariusz ankiety. W badaniu wzięli udział pacjenci Poradni Diabetologicznej CDL Barska we Włocławku. Warunkiem była pisemna zgoda pacjenta. Ankietę otrzymali pacjenci i przeprowadzono ją za ich zgodą. Wyniki. Jednym z czynników powodujących powikłania jest spożywanie alkoholu. Najwięcej badanych stwierdziło, że nie spożywa alkoholu (45%), ale bardzo duża część badanych przyznała, iż spożywa alkohol okazjonalnie (44%). Pacjenci wskazali, że alkohol może wywołać niedocukrzenie (51%). Najwięcej osób odpowiedziało, że alkohol źle wpływa na leczenie cukrzycy typu 2 (88%). Wskazując na rodzaj aktywności fizycznej badani najczęściej podawali spacery (48,4%) oraz jazdę na rowerze (25,8%). Pacjenci przyznali, iż aktywność fizyczną uprawiają raz w tygodniu (34%) lub nie uprawiają wcale (27%). Wnioski. Czynniki genetyczne i środowiskowe w zachorowalności cukrzycy typu 2 odgrywają bardzo ważną rolę.
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