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Zmiany czynności mioelektrycznej żołądka u osób z depresją i objawami dyspeptycznymi

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Wojtkiewicz P., Stępień A., Chojnacki J.

Folia Medica Lodziensia

2016

vol. 43

issue 1

17-37

Introduction: A chronic or recurrent pain and discomfort in the upper abdomen occurs frequently in depressive patients. The pathogenesis of these symptoms is complex and not fully understood. The aim of the study was to estimate the gastric myoelectrical activity in this group of patients. Material and methods: The study group consisted of 90 subjects, including 71 women and 19 men (mean age – 38.0±8.1). Among them three groups were divided: healthy subjects (K, n=30), depressive patients with dyspepsia (group II, n=30) and depressive patients with Helicobacter pylori infection (group III, n=30). All the subjects completed Hamilton Depression Scale and the gastric myoelectrical activity examination with Polygraph–Medtronic A/S (Denmark) was done before and after a liquid meal for 120 minutes. Results: Preprandial normogastria in depressive patients (group II, III) compared to healthy subjects (group K) was lower 79.5±8.1% vs 73.6±8.7% (p<0.01) and 79.5±8.1% vs 68.4±9.9 (p<0.001). The similar differences were recorded during postprandial time. Power ratio scale (PR) was also lower in depressive patients than in healthy subjects: 3.5±0.7 (K), 1.6±0.7 (group II), 1.7±0.8 (group III) – p<0.001, p<0.001 respectively. Conclusions: In depressive patients gastric myoelectrical activity is disturbed and probably causes chronic dyspepsia symptoms.

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1 Folia Medica Lodziensia

1 2016

1 Chojnacki J.

1 Stępień A.

1 Wojtkiewicz P.

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Zmiany czynności mioelektrycznej żołądka u osób z depresją i objawami dyspeptycznymi