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NOVEL CHITOSAN DERIVATIVES AS FILMS WITH AN ANTIMICROBIAL EFFECT

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Niemczyk A., El Fray M.
Progress on Chemistry and Application of Chitin and its Derivatives
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2013
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vol. 18
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issue 18
59-66
EN
This paper presents the results of chitosan acylation with linoleic (LA) and dilinoleic acid (DLA). The chemical structures of the new derivatives with different degrees of substitution of LA and DLA were assessed by Fourier transform infrared spectroscopy. Polymer films were prepared by solution casting and drying. The resistance of films to bacterial degradation was tested according ISO 846 standard: “Plastic-Evaluation of the Action of Microorganisms” and the antimicrobial properties were assessed using Gram-negative bacterium Escherichia coli and the fungi Candida albicans in an agar diffusion test. Bioassays showed an antimicrobial effect in direct contact with the material.
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