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EN
Introduction: Ischemic heart disease is the most common cause of death in the world. The lives of patients with vascular defects can be saved by coronary artery bypass grafting (CABG). However, it is associated with an increased risk of developing depression after surgery. Meterial and Methods: The aim of the study is to present the results of the latest research on postoperative depression after CABG, including studies describing the course of the disease, its consequences for the patient’s prognosis and treatment. The publications available on the PubMed platform published after 2011 were reviewed. Results: Depression before and after CABG affects 30–40% of patients, mostly women. Established after surgery and untreated, it persists for many years. The level of anxiety in patients decreases systematically after surgery. Indicators that may correlate with the patient’s postoperative depression, including cortisol, high sensitivity C-reactive protein (hsCRP) and oxidative stress biomarkers, are being investigated. The occurrence of depression in patients after CABG has a number of negative consequences. Those include: weaker response to treatment, greater chance of relapse, and increased readmission frequency and mortality. Treatment of patients with this disorder involves the use of antidepressants (most often SSRIs – selective serotonin reuptake inhibitor) and/or various types of psychotherapy with cognitive behavioral therapy (CBT) at the forefront. Conclusions: Depression following CABG decreases the quality of life and worsens patient prognosis. It is necessary to detect this condition early after surgery and to apply treatment, taking into account the cardiological disorders of the patient.
EN
The aim of the study was to answer the question as to whether transcranial direct current stimulation (tDCS) is more effective in reducing burnout syndrome in nurses than the commonly used individual psychotherapy. The study included 40 nurses from various health care facilities located in the Lesser Poland and Podkarpackie Voivodeship suffering from burnout syndrome. They were assigned to the experimental group while 20 to the control group. Two different therapy models were used: the experimental group (A) included 20 of the nurses treated with the use of transcranial direct current stimulation (tDCS), four times a week for 8 weeks, in sessions that lasted initially 10, then 15, 20, 25 and finally 30 minutes and the control group (B) included 20 of the nurses treated with individual psychotherapy employed for 8 weeks, once a week for 30 minutes. To evaluate the results we used: screening with a clinical interview, the Mini–Mental State Examination (MMSE), the Beck Depression Inventory and a Polish adaptation of the Italian questionnaire created by Massimo Sentinello (LBQ). Treatment was provided. The transcranial direct current stimulation (tDCS) used in Group A is more effective in reducing many symptoms than is the case with individual psychotherapy. Comparing the intragroup effects, it was found that the tDCS employed in Group A significantly reduced the intensity of depressive symptoms among the surveyed nurses [F (1.38) = 57.62; p <0.001; η2 = 0.603] while the individual psychotherapy used in Group B failed to produce a statistically significant effect [F (1.38) = 1.794; p = 0.188; η2 = 0.045]. These include a reduction of depression, a reduction in chronic psychophysical exhaustion, vegetative problem reduction, and the improvement of nurse-patient relations. Neurotherapy with the use of transcranial direct current stimulation (tDCS) is more effective in reducing burnout syndrome than the commonly used individual psychotherapy. It also helps to return these nurses to full professional activity. The studies presented above recommend the use of new neurotechnologies in therapy as a result of their usefulness and non-invasive character.
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vol. 17
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issue 3
165-171
EN
Purpose: The purpose of the study was to determine whether a link exists between early maladaptive schemas identified by Young et al. and depression in alcoholics. The relationships of schemas with selected alcohol dependence variables and suicidal thoughts in alcoholics were also checked. Material and methods: Seventy-seven alcohol addicts participated in the study – 19 women and 58 men. Young Schema Questionnaire (YSQ-S3), Beck’s Depression Inventory (BDI) and Michigan Alcoholism Screening Test (MAST) were used. Results: Based on the results obtained, 16 out of 18 schemas are positively and statistically correlated with depression among alcoholics. The strongest relationships were noted for emotional deprivation, social isolation/alienation and subjugation. Correlations between the schemas and the severity of addiction and the age of drinking initiation were also found. Differences in the intensity of some schemas occurred between people experiencing suicidal thoughts and people without these thoughts. Conclusions: There is a need to consider inclusion therapy focused on changing maladaptive schemas in alcoholics. This is especially true of the schemas of social isolation, emotional deprivation and subjugation. There is also a need for further research in this area.
PL
Cel: Celem przeprowadzonego badania było sprawdzenie, czy istnieje związek między wczesnymi nieadaptacyjnymi schematami wyróżnionymi przez Younga i współpracowników a depresją u osób uzależnionych od alkoholu. Podjęto też próbę odpowiedzi na pytanie o związki schematów z wybranymi zmiennymi dotyczącymi uzależnienia od alkoholu, a także występowaniem tendencji suicydalnych u alkoholików. Materiał i metody: W badaniu wzięło udział 77 osób uzależnionych od alkoholu – 19 kobiet oraz 58 mężczyzn. Zastosowano Kwestionariusz Schematów Younga (Young Schema Questionnaire, YSQ-S3), Skalę Depresji Becka (Beck’s Depression Inventory, BDI), Michigan Alcoholism Screening Test (MAST). Wyniki: Na podstawie otrzymanych wyników można stwierdzić, iż 16 z 18 schematów jest powiązanych dodatnio i istotnie statystycznie z poziomem depresji u osób uzależnionych od alkoholu. Najsilniejsze związki odnotowano w przypadku schematu deprywacji emocjonalnej, izolacji/wyobcowania i podporządkowania. Stwierdzono także związki schematów z głębokością uzależnienia oraz wiekiem rozpoczęcia picia. Różnice w natężeniu niektórych schematów występowały również między osobami doświadczającymi myśli samobójczych i osobami bez tych myśli. Wnioski: Należy rozważyć włączenie do terapii odwykowej pracy ukierunkowanej na zmiany destrukcyjnych schematów poznawczych występujących u osób uzależnionych. Dotyczy to zwłaszcza schematu izolacji społecznej, deprywacji emocjonalnej i podporządkowania. Istnieje również potrzeba prowadzenia dalszych badań tego obszaru problemowego.
EN
Aim: Self-destructiveness involves behaviours whose likely negative effect is mediated by additional factors, and the relationship between behaviour and damage is perceived as probable. The main objective of the research is to evaluate the behaviour of indirect self-destructiveness in patients with symptoms of anxiety and/or depression (compared to the persons without mental disorders-control group). Material and method: Clinical group included 40 patients of the Department of Adult Psychiatry at the Medical University of Lodz – people reporting symptoms of anxiety and/or depressed mood. The control group consisted of people without mental disorders. Polish version of Chronic Self-Destructiveness Scale (CS-DS) adapted by Suchanska and Hospital Anxiety and Depression Scale – Modified (HADS-M) by Snaith and Zigmond were used. The survey aimed at collecting sociodemographic data. Results: Differences were noticed between the clinical and control group in the following indirect autodestructive behaviours: Poor Health Maintenance, Lack of Planfulness, Personal and Social Neglects, Helplessness and Passiveness. Behaviours in all of those areas were more frequent in the clinical group. There were no significant differences noticed between groups in terms of: Transgression and Risk, alcohol use and smoking. Conclusions: Anxiety and depressive disorders promotes occurring of indirect self destructive behaviours.
PL
Cel: Autodestruktywność pośrednia obejmuje zachowania, których prawdopodobny negatywny skutek jest upośredniony przez dodatkowe czynniki. Głównym celem badania była ocena zachowań o charakterze autodestruktywności pośredniej u osób z objawami lęku i/lub depresji (w porównaniu z grupą kontrolną, złożoną z osób bez zaburzeń psychicznych). Materiał i metoda: Grupę kliniczną stanowiło 40 pacjentów Kliniki Psychiatrii Dorosłych Uniwersytetu Medycznego w Łodzi. Były to osoby zgłaszające się z objawami lęku i/lub obniżonego nastroju. Równoliczną grupę kontrolną stanowiły osoby bez zaburzeń psychicznych. Zastosowano polską wersję skali chronicznej autodestruktywności (Chronic Self-Destructiveness Scale, CS-DS) Kelley w adaptacji Suchańskiej oraz Szpitalną Skalę Lęku i Depresji w wersji zmodyfikowanej (Hospital Anxiety and Depression Scale – Modified, HADS-M) autorstwa Snaitha i Zigmonda. Opracowana przez autorów ankieta miała na celu zebranie podstawowych danych socjodemograficznych. Wyniki: Zaobserwowano różnice między grupą kliniczną a kontrolną w przypadku następujących grup zachowań pośrednio autodestruktywnych: zaniedbania zdrowotne, nieuważność, nieostrożność i brak planowania, zaniedbania osobiste i społeczne, pasywność (bierność). Zachowania z wymienionych obszarów okazały się częstsze w grupie klinicznej. Nie stwierdzono istotnych różnic między grupami w zakresie zachowań transgresyjnych, spożywania alkoholu i palenia papierosów. Wnioski: Można przypuszczać, że zaburzenia depresyjne i lękowe sprzyjają występowaniu zachowań pośrednio autodestruktywnych.
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vol. XVII
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issue 2
260-275
EN
The article is a review of neuroimaging studies performed during the Stroop paradigm based tasks among individuals suffering from unipolar and bipolar depression. The aim of the article is to highlight the validity od Stroop paradigm in neuropsychological and neuropsychiatric diagnosis of depressin, used as a tool for assessing cognitive functioning, but also claryfying the etiopathology of depressive disorders. The first of the article is a review of previous reports, describing resting brain activity abnormalities in affective disorders called neurocorrelates of depression. Then the most common cognitive dysfunctions represented by unipolar and bipolar patents will be discussed brefly and the impact of these dysfuctionts on Stroop test performance. In the last two parts of the article you can find a review of neuroimaging studies during Stroop task performance among healthy individuals and also the comparisons of brain activity during the Stroop interference effect in the group of healthy and depressive subjects. Different brain activity during stroop task among patients suffering from depression comaring with healthy individuals and some differences in brain pattern during the same cognitive task among unipolar and bipolar individuals may indicate the validity of Stroop test in neuropsychological and neuropsychiatric diagnosis.
EN
Most of the pathological changes in the spine begin with the physiological loss of intervertebral disc function. Discopathy of the lumbar spine leads to a significant deterioration in the quality of life, which is why the therapeutic team strives is to improve patients quality of life through actions aimed at reducing spinal dysfunction to an extent that allows for human functioning. The research aim was to determine the quality of life of patients who had been treat- ed as a result of discopathy of the lumbar spine and to establish the relationship between the experience of negative feelings and a subjective assessment of the quality of life with factors resulting frompatient socio-demographics. The study included 110 patients treated for lumbar discopathy. A diagnostic survey method was employed as a research technique, with the use of a proprietary survey questionnaire. Statistic analysis of the results was performedusing the statistical package PQStat v1.6.6. Subjective evaluation of patients quality of life in 66 persons (60%) was at an average level, only 6 (5.45%) respondents rated the quality of their lives as being higher. Those living in towns of up to 50,000 residents rated their quality of life higher (6.21), with the lowest level being reported by those living in the countryside (4.95). Age did not influence significantly the quality of life, but older people most often experienced pain (p=0.4). Analysis of variance did not show statistically significant differences between marital status and respondent quality of life (p = 0.53) but did show significant differences between education levels and the incidence of negative feelings such as fear, anxiety or depression. Socio-demographic variables: such as gender, age and marital status do not significantly differentiate the quality of life of the respondents. There is a relationship between experiencing negative feel ings and educational levels. The lower the education level obtained, the more often negative feelings are experienced. The experiencing of negative feelings and disease duration are variables that reduce the quality of life of respondents. ------------------------------------------------------------------------------------------------------------------------------------
EN
Aim: While the effect of antidepressants on platelet functions is relatively well studied, there are few studies comparing platelet parameters, such as platelet count, between elderly patients with unipolar depression and non-depressed elderly subjects. Therefore, the aim of the study was to determine if there are differences in platelet count in elderly patients with unipolar depression (DEP) compared with non-depressed elderly patients (nonDEP) using case-control analysis. Methods: We measured platelet count in 582 (DEP: n = 291, nonDEP: n = 291) Caucasian in-patients aged ≥60. The mean age of the study subjects was 77.2 years, there were 243 (83.5%) women in both study groups. Results: The mean platelet count was significantly (p = 0.02) lower in the DEP group (241.6 ± 82.0) compared with the nonDEP group (263.6 ± 107.2). We also found that platelet count was not correlated with age. Conclusions: Compared with non-depressed controls, elderly patients with depression have decreased number of platelet cells. This, combined with the known effect of antidepressants on platelet agreeability, may translate into an increased risk of bleeding complications in the course of antidepressive treatment in elderly patients. Careful monitoring of platelet parameters is therefore recommended in the clinical population of elderly depressed patients.
PL
Cel: O ile wpływ leków przeciwdepresyjnych na funkcje płytek krwi jest stosunkowo dobrze zbadany, o tyle niewiele jest badań porównujących parametry płytek krwi (takie jak liczba płytek krwi) u osób w podeszłym wieku z depresją jednobiegunową i bez depresji. Celem badania było określenie, czy istnieją różnice w liczbie płytek u pacjentów w podeszłym wieku z depresją jednobiegunową (DEP) w porównaniu z pacjentami w podeszłym wieku (nonDEP), za pomocą metody analizy case control. Metody: Oceniono liczbę płytek krwi u 582 (DEP: n = 291, nonDEP: n = 291) pacjentów rasy kaukaskiej w wieku ≥60 lat. Średni wiek badanych wynosił 77,2 roku, w obu grupach było 243 (83,5%) kobiet. Wyniki: Średnia liczba płytek krwi była istotnie statystycznie mniejsza (p = 0,02) w grupie DEP (241,6 ± 82,0) w porównaniu z grupą nonDEP (263,6 ± 107,2). Stwierdzono ponadto, że liczba płytek krwi nie korelowała z wiekiem. Wnioski: W porównaniu z grupą kontrolną u pacjentów w podeszłym wieku z depresją liczba płytek krwi była mniejsza. Fakt ten, w połączeniu ze znanym wpływem leków przeciwdepresyjnych na agregację płytek krwi, może przełożyć się na zwiększone ryzyko wystąpienia powikłań krwotocznych w trakcie leczenia przeciwdepresyjnego u pacjentów w podeszłym wieku. Zaleca się ostrożne monitorowanie parametrów płytek w populacji klinicznej u pacjentów w podeszłym wieku.
EN
Obesity is a growing public health concern in modern societies. This is a major health concern. It has been implicated as a risk factor for several physical illnesses, functional limitations and poor quality of life. However, while the physical consequences of obesity are well established, the relationship between obesity and mental health is still unclear. The question this study aimed to answer was whether the associations between obesity and mood disorders are occurring in the sanatorium patients population. The results found a significant association between obesity and mood disorders. It is still unclear whether the relationship between obesity and depression is causal, and if so, whether obesity causes depression or depression causes obesity. Implications for health care providers and suggestions for future research are discussed.
EN
Depressive disorders have become one of the greatest health problems of the modern society, with about 350 million people suffering from depression around the world (WHO). The aim of this study was to determine the prevalence of symptoms of depressed mood and symptoms indicating the possibility of depression or its progression among young people living in the city of Szczecin, Poland. Data from 150 students (107 women and 43 men) from one of the local universities constituted the material for this anonymous study which was based on the Beck Depression Inventory – 21 questions assessing the severity of depressive symptoms. Our results showed that 78% of women and 89% of men did not show symptoms of depression (Fig. 1). The incidence of mild depressive episodes was revealed in 15% of women and 7% of men, moderate episodes in 3% of women and 2% of men, and severe depression in 4% of women and 2% of men.
EN
Chronic obstructive pulmonary disease is one of the most important health problems and one of the most common chronic diseases. The occurrence of COPD is associated with a particular dimension of physical suffering, the source of which is the difficulty in breathing. A significant percentage of patients experience the mental consequences of illness such as depression and anxiety disorders. The aim of the study was to analyze the prevalence of depressive symptoms in patients with medium-severe and severe forms of COPD and to assess the cost of coexistence of depression in this group of patients. The retrospective study, based on medical records, included two groups of patients: Group 1- 63 persons and Group 2– 60 persons. The study evaluated the following parameters: degree of severity of COPD according to Global Initiative for Chronic Obstructive Lung Disease (GOLD), degree of severity of dyspnea using the mMRC scale of dyspnea developed by the Medical Research Council and occurrence of depressive symptoms and their severity using the Beck Depression Scale questionnaire. Patients were treated at the CENTER for Respiratory Medicine between January 2016 and December 2016. Results of our study showed that in both treatment groups analysis of the answers received from the Beck’s Depression Scale questionnaire revealed that all these patients have depressive symptoms of varying severity.
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vol. 17
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issue 2
129-136
EN
Alopecia areata (also known as spot baldness) is a disease with multifactorial aetiology, including genetic, hormonal, autoimmune and  psychological factors as well as nervous system disorders. This disorder belongs to  the group of dermatological conditions modified by psychological factors. Clinical experience indicates that stress and psychological aspects contribute significantly to the onset and/or exacerbation of alopecia areata. Pharmacological treatment of this dermatosis is often ineffective or insufficient. Therefore, a holistic approach to the disease, including both medical and  psychological aspects, is  crucial. It  is  emphasised in  the subject literature that some forms of  psychotherapy and pharmacotherapy used in patients with alopecia areata improve their psychophysical condition, and, consequently, stimulate the regrowth of their hair. Research has shown that cognitive-behavioural therapy complements dermatological treatment of alopecia areata, improving the quality of life of patients. The aim of cognitive and behavioural techniques is, on the one hand, to change the maladaptive negative convictions about oneself, the world, and the disease, and, on the other hand, to acquire the ability to cope with negative emotional states and difficult situations, such as a disease. The aim of the paper is to present the results of a literature review on the efficiency of pharmacotherapy and the role of cognitive-behavioural therapy in alopecia areata.
PL
Łysienie plackowate (alopecia areata) jest chorobą o wieloczynnikowej etiologii, w której uwzględnia się czynniki genetyczne, hormonalne, autoimmunologiczne i psychiczne oraz zaburzenia w zakresie układu nerwowego. Schorzenie to zalicza się do grupy chorób dermatologicznych modyfikowanych przez czynniki psychologiczne. Doświadczenie kliniczne wskazuje, że stres i aspekty psychologiczne mają znaczący udział w wystąpieniu i/lub zaostrzeniu łysienia plackowatego. Leczenie farmakologiczne tej dermatozy nierzadko okazuje się nieskuteczne albo niewystarczające. Istotne jest zatem holistyczne podejście do choroby, obejmujące zarówno aspekt medyczny, jak i psychologiczny. W literaturze przedmiotu podaje się, że niektóre formy psychoterapeutyczne i farmakoterapia stosowane u pacjentów z łysieniem plackowatym poprawiają ich stan psychofizyczny, a w konsekwencji wpływają także na odrost włosów. Badania wskazują, że terapia poznawczo- -behawioralna to istotne uzupełnienie dermatologicznego leczenia łysienia plackowatego, przyczyniające się do poprawy jakości życia pacjentów. Celem technik poznawczych i behawioralnych jest z jednej strony zmiana nieadaptacyjnych negatywnych przekonań (zarówno na temat samego siebie czy świata, jak i choroby), a z drugiej nabycie umiejętności radzenia sobie z negatywnymi stanami emocjonalnymi i trudnymi sytuacjami (np. z chorobą). W pracy zaprezentowano wyniki przeglądu literatury dotyczącej efektywności farmakoterapii stosowanej w łysieniu plackowatym oraz techniki terapii poznawczo-behawioralnej, które można wykorzystać w leczeniu tej dermatozy, z uwzględnieniem istotnych problemów charakterystycznych dla pacjentów z chorobami przewlekłymi.
EN
Although randomized trials have proven the benefit of revascularization with the use of carotid endarterectomy (CEA) or stenting (CAS) for appropriate patients, health care purchasers increasingly look beyond clinical outcome toward measures of health-related quality of life (HRQoL) in apportioning limited resources. 36 patients after TIA participated in this study. One group (n=18) had undergone CEA, whereas the second group (n=18) had undergone CAS. Both groups were matched according to age and sex. The Short Form 36 (SF-36) was used to assess the differences in patient-perceived HRQoL in two groups of patients who had suffered minor cerebral ischemic events. No significant difference in health profile between the CEA and CAS was detected for the eight SF-36 domains. However, the CEA group rated a significantly improved change in general health after one year compared with the CAS group (p<0.001). A greater proportion of the CEA group comparing to the CAS group thought their treatment had been successful and that their health had been improved (p<0.001). Both groups shared the same level of anxiety over potential future cerebral ischemic events (p=0.3). Patients' perception of HRQoL measured by the SF-36 domains was almost identical between the CEA and CAS apart from a small but significant improvement in self-reported overall health in the CEA group after one year follow up. HRQoL outcome measures may be of value in future clinical trials of cerebral revascularization to compare the effectiveness of carotid revascularization with the particular method of operation.
EN
Backgorund Decreased affective efficiency, preceded by emotional problems, is a common advanced-age disorder which can lead to depression. Aim The aim of this study was to assess the relationship between depressive symptoms experienced by elderly people and their sociodemographic data, self-reported health status, physical fitness, functional capacity, and history of falls. Material and methods The study involved 304 individuals aged 65-100 years. The research instruments were the Geriatric Depression Scale-Short Form, the Barthel Scale, and the Background Survey Geriatric Questionnaire. Results Depression was more common among the elders who had a lower education level, lived alone, were in a worse financial position, and among those whose families were unprepared to provide them with informal care (p < 0.05). Conclusions Depressive symptoms observed in the respondents were significantly related to their sociodemographic data, reduced ability to perform daily activities, low self-reported health status and physical fitness, and recurrent falls.
EN
Temporomandibular disorders (TMD) constitute a group of clinical problems involving the masticatory muscles, the temporomandibular joint and associated structures. An etiological connection of TMD with psychological factors was proposed as early as the 1980’s. Indeed, the interdependence of psychological and health aspects in the patient’s treatment, place light upon the more important variables contributing to the various mental disorders that may accompany TMD. Current literature suggests a close relationship between TMD and selected psychological factors, such as personality traits, stress, depression, anxiety, and catastrophizing. Of note, anxiety-depressive disorders, somatisation and catastrophizing contribute to chronic TMD, mainly in the form of myofascial pain. Hence, knowledge of the influence of psychological factors affecting TMD, enables the identification of patients with an increased risk of chronic painful TMD.
EN
Aim The objective of the study was to assess psychological aspects of the quality of life of patients in long-term stationary care. Material and methods The research was carried out from December 2018 to February 2019. The study was conducted among 92 patients of the Nursing and Care Institution. The research method was a diagnostic survey, while the research technique was a survey. The research tools were the author's questionnaire and the Beck’s Depression Scale. The results obtained from the questionnaires were subjected to statistical analysis. The differences between the variables were verified using the chi-square independence test and the Kruskal-Wallis test, assuming a significance level of p<0.05. Results The occurrence of depression in the respondents was assessed using the Beck Depression Scale. Lack of depression was found in 40.2% of the respondents, mild depression in 45.7% and moderate depression in 14.1%. Analysis of the research showed that the marital status of the respondents significantly affected their incidence of depression. It was found that moderate depression was 38.4% more common (p=0.0409). The most numerous group of respondents were respondents, who often experienced anxiety (80.4%) and irritability (56.5%). The most common situations causing irritability and anxiety in subjects is lack of independence (53.3%), which has a significant impact on the feeling of loneliness among the subjects. Conclusions The most common situations causing irritability and anxiety in subjects result from a lack of independence, which affects their sense of loneliness. Subjects who did not spend time among other patients more often felt helpless and confused.
EN
Background: Both depressive disorders and nicotine use are proven and important risk factors of dementia. The purpose of this study was to verify if cigarette smoking and depression symptoms together are disadvantageous for the prognosis in mild cognitive impairment. Material and methods: A total of 43 patients with a diagnosis of mild cognitive impairment were included in the study. ADAS-Cog was performed upon inclusion in the study and again at least 2 years later. Additionally, patients with ≥18 points in MADRS were qualified as depressive. The Fagerström scale for nicotine dependence was administered to smokers. Results: Our study shows a relation between severity of depressive symptoms and further deterioration of cognitive functions according to ADAS-cog scale. Regression analysis revealed that smoking associated with severity of depressive disorders is also correlated with the progression of cognitive impairment. Conclusions: The results of our study are based on a small number of subjects and should be regarded as early findings. Moreover, nicotine dependency should not be regarded as an isolated factor affecting mood disorders and cognitive impairment progression. Further studies on larger groups of patients and using more sensitive methods of cognitive function assessment are needed.
EN
Aim of the study. Study aims were to compare neuropsychological functioning of depressed bipolar patients and healthy controls and to estimate relationship between severity of depressive symptoms and cognitive functioning. Method. Cognitive functions were examined in 30 depressed bipolar patients aged 18-68 (M=45,6, SD= 12,6; 18 women and 12 men) who fulfilled ICD-10 criteria for depressive episode (Hamilton Depression Rating Scale score ≥11). The comparison group consisted of 30 healthy subjects aged 23-71 (M=46, 20 women and 10 men) matched in age, years of education and gender to bipolar group. A neuropsychological battery assessed executive functions and working memory. Results. The bipolar patients in depression revealed neuropsychological deficits in working memory and some aspects of executive functions in comparison to healthy group. Only in WCST test both groups received similar results. Neuropsychological functioning seems to be independent of the severity of depressive symptoms. Discussion. Different aspects of working memory and executive functions are impaired in depression period of bipolar disorder and they seem independent of the severity of depressive symptoms. These results are consistent with previous reports. Conclusions. In patients with bipolar depression cognitive assessment should be taken into account in the diagnosis and the disturbances in executive functions and working memory should be treated with neuropsychological rehabilitation and / or pharmacotherapy.
EN
Introduction. Studies on the dietary habits of depressive patients demonstrate frequent deviation result- ing in the development of many diseases. Purpose. The aim of the study was to assess the efficacy of weight reduction diet in patients with depres- sive disorders, including the assessment of changes in the intake of major nutrients that may promote al- terations in body composition during a three-month observation. Methods. The study included 77 people with excessive body weight (45 women and 32 men; average age of women 49.3±10.3 years and men 47.1± 1.2 years) treated for recurrent depressive disorders and being on a 3-month weight reduction diet. The study patients underwent anthropometric measurements and their body composition was determined with electric bio-impedance. Results. Mean weight loss in women was 2.7±2.5kg, and in men 2.0±5.6kg. There was a decrease in fat mass in women by an average of 1.8±5.7kg and in men by 1.3±7.1kg. A statistically significant reduc- tion was reported in the mean waist circumference (3.8±3.7cm) and hips (2.0 ± 1.9cm) among women. Diet modification brought a decrease in the energy value of daily diet and reduction in the supply of ma- cronutrients. Conclusions. The long-term effect of the nutritional therapy indicates the need for intensified dietary ed- ucation, both in terms of the number of dietary trainings and intensive cooperation between patient and dietician for proper selection of food products. The cooperation should not only be related to diet correc- tion, but is also expected to motivate physical activity and lifestyle changes.
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Background. During the last few decades, adiposity has become a relatively common phenomenon worldwide. The available data on the effects of pro-inflammatory factors in both depression and adiposity has been attracting great attention. Aim. We sought to assess the prevalence of -889C>T IL-1α, -31T>C and -511C>T IL-1β, -330T>G IL-2 and -174G>C IL-6 genes and their association with adiposity and depression in Polish subjects. Methods. A cohort study was conducted in 2013/2014, covering a sample of 297 individuals (217 female and 80 male). Anthropometric data was handled using the BIA analysis method, while for genotyping PCR-RFLP techniques were used. Results. A positive correlation between depression and anthropometric parameters: adipose tissue (in kg) and adipose tissue (in %) (R=0.135 and p=0.02, R=0.114 and p<0.05, respectively) was found. No association between studied polymorphisms and depression was observed. Conclusion. Although it was not possible to demonstrate any influence of the studied polymorphisms as the genetic modulator of depression, authors believe that the presented data are noticeable and may provide the basis for future studies on larger groups.
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