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The P wave duration in patients with atrial fibrillation undergoing cryoballoon pulmonary vein isolation. Preliminary results

100%
Zawadzki J. M., Adamowicz J., Sławuta A., Gajek A., Zyśko D., Gajek J.
|
2018
|
vol. 1
|
issue 1
44-47
EN
The pulmonary vein isolation remains the major target of atrial fibrillation ablation. The cryoablation lesions in the left atrium are supposed to disconnect the pulmonary vein from the atrium on the atrial side of the orifices. We hypothesized that the cryoballoon pulmonary vein isolation could result in the prolongation of the P wave duration. The aim of the study was to assess the duration of the P wave in 12-lead electrocardiogram and the influence of pulmonary vein isolation on this parameter. The study group included 21 patients (11 women and 10 men) 66.2+/-7.4 years of age undergoing cryoballoon ablation. In order to measure the P wave duration, we used the constant acquisition of electrogram and the electrocardiographic channels provided by LABSYSTEM™ Pro EP Recording System (Boston Scientific), magnifying the leads 64x. We calculated the duration in the simultaneously recorded 12-lead ECG, from the beginning of the earliest recorded P wave deflection, until the end of the latest P-wave deflection recorded in any lead. The P wave duration in the entire study group was 141.7+/-12.5 ms before the ablation and increased significantly to 151.1+/-11.5 ms (p<0.05) after the procedure. The respective values in women were 144.1+/-4.3 vs. 156.0+/-4.7 ms (p<0.01) and 139.1+/-4.6 vs. 145.6+/-4.5 ms in men (p<0.05). The mean standard deviation of every single measurement considered separately was 4.4+/-2.1 ms before the cryoablation and 4.6+/-1.8 ms after the procedure (p= not significant (n.s).), indicating very good reproducibility of the measurements. We concluded, that cryoballoon pulmonary vein isolation leads to the prolongation of the measured P wave duration. It seemed to result from conduction disturbances created by cryoablation. The clinical significance of the observed changes remains unknown.
2
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Content available

The P wave duration in patients with atrial fibrillation undergoing cryoballoon pulmonary vein isolation. Preliminary results

100%
Zawadzki J. M., Adamowicz J., Sławuta A., Gajek A., Zyśko D., Gajek J.
European Journal of Translational and Clinical Medicine
|
2018
|
vol. 1
|
issue 1
44-47
EN
The pulmonary vein isolation remains the major target of atrial fibrillation ablation. The cryoablation lesions in the left atrium are supposed to disconnect the pulmonary vein from the atrium on the atrial side of the orifices. We hypothesized that the cryoballoon pulmonary vein isolation could result in the prolongation of the P wave duration. The aim of the study was to assess the duration of the P wave in 12-lead electrocardiogram and the influence of pulmonary vein isolation on this parameter. The study group included 21 patients (11 women and 10 men) 66.2+/-7.4 years of age undergoing cryoballoon ablation. In order to measure the P wave duration, we used the constant acquisition of electrogram and the electrocardiographic channels provided by LABSYSTEM™ Pro EP Recording System (Boston Scientific), magnifying the leads 64x. We calculated the duration in the simultaneously recorded 12-lead ECG, from the beginning of the earliest recorded P wave deflection, until the end of the latest P-wave deflection recorded in any lead. The P wave duration in the entire study group was 141.7+/-12.5 ms before the ablation and increased significantly to 151.1+/-11.5 ms (p<0.05) after the procedure. The respective values in women were 144.1+/-4.3 vs. 156.0+/-4.7 ms (p<0.01) and 139.1+/-4.6 vs. 145.6+/-4.5 ms in men (p<0.05). The mean standard deviation of every single measurement considered separately was 4.4+/-2.1 ms before the cryoablation and 4.6+/-1.8 ms after the procedure (p= not significant (n.s).), indicating very good reproducibility of the measurements. We concluded, that cryoballoon pulmonary vein isolation leads to the prolongation of the measured P wave duration. It seemed to result from conduction disturbances created by cryoablation. The clinical significance of the observed changes remains unknown.
3
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Content available

Recent advances on diagnosis and treatment of osteoid osteoma

58%
Gryglewski K., Napora J., Wałejko S., Mazurek T.
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|
vol. 87
|
issue 1
25-31
PL
Kostniak kostnawy jest nowotworem łagodnym o charakterystycznym ognisku (nidus) w badaniach radiologicznych. Najczęstszym objawem prowadzącym do jego rozpoznania jest silny, nocny ból, reagujący na niesteroidowe leki przeciwzapalne. Tomografia komputerowa jest metodą z wyboru w diagnostyce i lokalizacji zmiany. Kostniak kostnawy może wygoić się samoistnie, toteż leczenie zachowawcze jest jedną z metod postępowania. Resekcja otwarta była standardowym leczeniem kostniaka kostnawego do czasu wprowadzenia termoablacji prądem wysokiej częstotliwości (RFA) na początku lat 90. XX wieku. Obecnie istnieje kilka metod leczenia małoinwazyjnego. RFA pod kontrolą tomografii komputerowej jest aktualnie uważana za złoty standard terapeutyczny leczenia kostniaka kostnawego. W wielu przypadkach występuje znaczne opóźnienie pomiędzy początkiem charakterystycznych objawów a postawieniem prawidłowej diagnozy i skutecznym wyleczeniem. W związku z tym istotna jest znajomość obrazu klinicznego, prawidłowy dobór metod diagnostycznych i leczniczych.
EN
Osteoid osteoma (OO) is a benign bony lesion with a characteristic radiologic feature of x-ray focus (nidus). The most common symptom indicating diagnosis is strong nocturnal pain that eases with nonsteroidal anti-inflammatory drugs (NSAID). Computed tomography (CT) is a method of choice for diagnosing and localizing the tumor. Osteoid osteoma can regress spontaneously, thus conservative treatment is one of the methods of choice. In the past open resection surgery had been a standard management of osteoid osteoma until radiofrequency ablation (RFA) was discovered in the early 1990s. Nowadays, there are a few minimally invasive treatment techniques that are used. CT-guided radiofrequency ablation is considered a gold standard technique these days. Many cases occur with late diagnosis, and delayed treatment despite of characteristic symptoms. Therefore, it is crucial to be familiar with the clinical features of osteoid osteoma, proper diagnostic patterns, and treatment schemes.
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