Full-text resources of PSJD and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl
Preferences help
enabled [disable] Abstract
Number of results

Results found: 13

Number of results on page
first rewind previous Page / 1 next fast forward last

Search results

Search:
in the keywords:  cortisol
help Sort By:

help Limit search:
first rewind previous Page / 1 next fast forward last
EN
Body response is a key element of the periodization of any training unit. The main control systems in the human body are the nervous and endocrine systems. The study aims to examine the effect of bench press at a specified movement tempo on post-exercise blood testosterone and cortisol levels. The study involved 16 men (experience in resistance training 5.5 ± 1.3 years, aged 24 ± 2 years, body weight 86.1 ± 7.2 kg, and 1RM 125 ± 17 kg). The first stage of the test focused on determining the maximum force based on a single bench press with the highest possible external load (1RM). The second stage included the main test, i.e. bench press. The participants were asked to perform 5 sets successively, with an external load of 70% of an individual 1RM and as many repetitions as possible. The tempo of the exercise was precisely specified. The metronome was used to set a bench press tempo. The movement tempo included time under tension (TUT) 2/0/2/0. TUT means the total time of muscle tension during one repetition. The tests showed significant changes in cortisol levels recorded 30 minutes after exercise, amounting to 13.75 (±4.60) at F=9.16 and p=0.006. and 60 minutes after exercise, amounting to 11.37 (±4.17) at F=19.46 and p=0.0002. No significant statistical values were found for testosterone levels. This study brings additional evidence of the importance of hormonal responses in muscle strength training.
EN
The aim of the present study was to investigate the effect of Finnish sauna bathing on a white blood cell profile, cortisol levels and selected physiological indices in athletes and non-athletes. The study evaluated 9 trained middle-distance runners and 9 male non-athletes. The subjects from both groups participated in 15-minute sauna sessions until their core temperature rose by 1.2°C (mean temperature in the sauna room was 96° ± 2°C; relative humidity was 15 ± 3%) with a 2 minute cool down with water at a temperature of 19-20°C. Body mass was measured before and after the session and blood samples were taken for tests. Rectal temperature was monitored at five-minute intervals during the whole session. Serum total protein, haematological indices and cortisol levels were determined. Sauna bathing caused higher body mass loss and plasma volume in the athletes compared to the group of non-athletes. After the sauna session, an increased number of white blood cells, lymphocyte, neutrophil and basophil counts was reported in the white blood cell profile. Higher increments in leukocyte and monocyte after the sauna bathing session were recorded in the group of athletes compared to untrained subjects. The obtained results indicated that sauna bathing stimulated the immune system to a higher degree in the group of athletes compared to the untrained subjects.
OncoReview
|
2017
|
vol. 7
|
issue 4
176-179
EN
Cushing’s disease is a rare endocrine disorder caused by ACTH-secreting pituitary adenoma. The treatment of choice is a transsphenoidal surgery performed by an experienced neurosurgeon. However, in some patients adjuvant treatment is required due to ineffective surgery or disease recurrence. This article discusses new aspects of pharmacological treatment of ACTH-dependent hypercortisolism in light of a recent publication reporting the efficacy and safety of once a month pasireotide LAR injections in Cushing’s disease.
EN
The main objective of this study was to determine the effect of stress of a practical, thirty-hour driving course on changes in salivary cortisol concentration and on changes in systolic and diastolic blood pressure. The second objective was to determine the relation between the style of coping with stress (psychological indicator) and changes in the assessed biological parameters. All volunteers aged 18-30 years completed the Coping Inventory for Stressful Situations (CISS) before the start of the course. They were divided into control (n=15) and experimental (n=18) groups. In the experimental group saliva samples to measure cortisol were collected from each participant: before the start of the course, before the 1st, 13th and 28th driving hour, and blood pressure was measured before the course, during the 15th and 30th hour of the course. Participants in the control group had one saliva sample taken and their blood pressure was measured once at the same time. The results suggest that cortisol concentration in saliva correlates with the hour of the course. Systolic and diastolic pressure also correlates with the hour of the course. CISS test related differences among the individuals in copying with stress (sex as well as age-related) but they did not correlate with the cortisol and blood pressure responses. A driving course is a stress factor that causes changes in salivary cortisol concentration and systolic and diastolic blood pressure. The style of coping with stress does not correlate with changes in the salivary cortisol concentration during the course. Changes in systolic and diastolic blood pressure during the driving course do not depend on the way of coping with stress.
EN
This study examined the effects of a 6-week non-failure strength training program in youth tennis players. Twenty tennis players (age: 15.0 ± 1 years, body height: 170.9 ± 5.1 cm, body mass: 63.3 ± 9.1 kg) were divided into experimental and control groups. Pre and post-tests included half squats, bench press, squat jumps, countermovementjumps and side-ball throws. Salivary cortisol samples were collected, and the Profile of Mood States questionnaire was used weekly during an anatomical adaptation period, a main training period and after a tapering week. The results showed that, after the main training period, the experimental group significantly improved (p<0.05) in mean and peak power output and in the total number of repetitions during the half-squat endurance test; mean force, power and velocity in the half-squat power output test; Profile of Mood States (in total mood disturbance between the last week of the mean training period and the tapering week); and in squat-jump and countermovement-jump height. Moreover, significant differences were found between the groups at the post-tests in the total number of repetitions, mean and peak power during the half-squat endurance test, mean velocity in the half-squat power output test, salivary cortisol concentration (baselines, first and third week of the mean training period) and in the Profile of Mood States (in fatigue subscale: first and third week of the mean training period). In conclusion, a non-failure strength training protocol improved lower-limb performance levels and produced a moderate psychophysiological impact in youth elite tennis players, suggesting that it is a suitable program to improve strength. Such training protocols do not increase the total training load of tennis players and may be recommended to improve strength.
EN
Adequate levels of strength and flexibility are important for the promotion and maintenance of health and functional autonomy as well as safe and effective sports participation. The aim of the present study was to analyze the effects of 8 weeks of strength training with or without inter-set static stretching on strength, flexibility and hormonal adaptations of trained men. Sixteen trained men were randomly divided into 2 groups: the static stretching group (SSG) and passive interval group (PIG). All participants performed 24 training sessions 3 times a week. The test and retest of 8RM, strength, flexibility, cortisol and growth hormone concentration in pre and post test conditions were also evaluated. To compare the differences between and within groups in pre- and post-training tests, ANOVA with repeated measures was performed (SSGpre x SSGpost; PIGpre x PIGpost; SSGpost x PIGpost). An alpha level of p<0.05 was considered statistically significant for all comparisons. Both groups showed significant increases in strength (SSGpre vs. SSGpost; PIGpre vs. PIGpost) in the same exercises for leg extension (LE) and Low Row (LR). Specifically, in the SSG group, the parameters for LE were (p = 0.0015 and ES = 2.28 - Large), and the parameters for LR were (p = 0.002 and ES = 1.95 - Large). Moreover, in the PIG group, the parameters for LE were (p = 0.009 and ES = 1.95 - Large), and the parameters for LR were (p = 0.0001 and ES = 2.88 - Large). No differences were found between the groups (SSGpost vs. PIGpost). Both groups showed significant increases in flexibility but in different joints (SSGpre vs. SSGpost; PIGpre vs. PIGpost). In the SSG group, only three joints showed significant increases in flexibility: shoulder extension (p = 0.004 and ES = 1.76 - Large), torso flexion (p = 0.002 and ES = 2.36 - Large), and hip flexion (p = 0.001 and ES = 1.79 - Large). In the PIG group, only three joints showed increases in flexibility: horizontal shoulder abduction (p = 0.003 and ES = 2.07 - Large), hip flexion (p = 0.001 and ES = 2.39 - Large), and hip extension (p = 0.02 and ES = 1.79 - Large). In-between group analyses (SSGpost x PIGpost) revealed differences in two joints: shoulder extension (p = 0.001) and horizontal shoulder abduction (p = 0.001). Hormonal profiles showed no significant differences in cortisol secretion or growth hormone concentration. In conclusion, both studied strength protocols (with and without inter-set static stretching) resulted in flexibility and strength gains without an effect on the anabolic and catabolic hormonal profile.
PL
Aktywacja cytokin i rozwój procesu zapalnego jest wynikiem złożonej interakcji w patogenezie wielu schorzeń ośrodkowego układu nerwowego. Zarówno cytokiny o działaniu prozapalnym, jak i przeciwzapalnym są wytwarzane podczas odpowiedzi immunologicznej. Pomiar cytokin w płynie mózgowo-rdzeniowym może być stosowany jako dodatkowe narzędzie w procesie diagnostycznym pacjentów z chorobami OUN. W zakażeniach OUN o różnej etiologii, stężenia IL-1, IL-6, IL-8, IL-10 i TNF-α są zazwyczaj podwyższone. Zmiany ich poziomu pod wpływem antybiotykoterapii nie są w pełni wyjaśnione. Niektóre cytokiny, jak IL-6 są nie tylko parametrem zapalnym, ulegają również podwyższeniu stanach chorobowych o etiologii niezapalnej, jak np. u pacjentów z krwotokiem podpajęczynówkowym. Rola TNF-α jest znana w zaburzeniach neurodegeneracyjnych, gdzie zarówno w surowicy, jak i w CSF zwiększa się poziom czynników prozapalnych, w tym TNF-α, IL-1 i IL-6. Ocena poziomu cytokin w płynie mózgowo-rdzeniowym pacjenta może być dodatkowym narzędziem oceny w leczeniu zaburzeń ośrodkowego układu nerwowego u dzieci, zwłaszcza tych o podłożu zapalnym. Metody leczenia wpływające na stężenia określonych cytokin mogą być przyszłym narzędziem w leczeniu chorób zapalnych OUN.
EN
Cytokine activation and inflammatory process is a result of complex interaction in the pathogenesis of various central nervous system disorders (CNS). Both proinflammatory and anti- -inflammatory cytokines are produced during immune response. Cytokines measurement in the cerebrospinal fluid (CSF) may be used as an additional tool in patients assessment. In the state of CNS infection, IL-1, IL-6, IL-8, IL-10 and TNF-α levels are typically elevated. Cytokine level alterations after antibiotic therapy are not fully elucidated. Some cytokines, like IL-6, are not only an inflammatory parameter, being elevated in patients with subarachnoid haemorrhage. The role of TNF-α is known in neurodegenerative disorders, where levels of proinflammatory factors, including TNF-α, IL-1 and IL-6, are increased both in serum and in CSF. Assessment of cytokine levels in CSF may be an additional evaluation tool in the management of CNS disorders in children, especially those of inflammatory background. Therapeutic agents for specific cytokines could be a future tool in the treatment of inflammatory diseases.
PL
Kortyzol jest jednym z kluczowych hormonów dla zachowania homeostazy w organizmie człowieka, co zostało wykazane w wielu badaniach u osób zdrowych. Zbadano również prawidłowy rytm uwalniania kortyzolu. Stanowi to podstawę do dalszych badań zaburzeń wydzielania kortyzolu w różnych schorzeniach, szczególnie tych objawiających się zaburzeniami neuropsychiatrycznymi. Zaburzenia ze spektrum autyzmu stanowią jeden z najintensywniej badanych problemów zdrowotnych ze względu na objawy osiowe autyzmu, takie jak lęk czy zaburzenia społeczne i zachowania, jak również dodatkowe objawy, takie jak zaburzenia snu czy czynnościowe przewodu pokarmowego. Przeprowadziliśmy systematyczny przegląd piśmiennictwa w bazie PubMed, uwzględniając artykuły spełniające kryteria wyszukiwania “autism” (autyzm) i “cortisol” (kortyzol). Po pierwotnej selekcji istotnych prac, przeanalizowaliśmy 56 artykułów. Omawianie wyników podzieliliśmy na podkategorie, dotyczące profilu dobowego kortyzolu, podstawowych jego poziomów, wydzielania przy obudzeniu oraz poziomów w reakcji na konkretny bodziec. Analizowane dane były niejednoznaczne. Zaburzenia profilu dobowego kortyzolu, podstawowego jego poziomu, wydzielania przy obudzeniu oraz poziomów w reakcji na stresor stanowiły jednakże częste zjawisko wśród badanych osób z zaburzeniami ze spektrum autyzmu. Nieliczne dane dotyczące wpływu prowadzonych działań terapeutycznych wskazywały na częściej osiąganą kliniczną poprawę niż zmiany w stężeniu kortyzolu. Poniższy przegląd piśmiennictwa powinien stanowić podstawę do przeprowadzenia randomizowanych badań klinicznych na dużej, homogennej grupie, by uzyskać bardziej wnikliwe spojrzenie na rolę kortyzolu w zaburzeniach ze spektrum autyzmu.
EN
Cortisol is a hormone crucial for homeostasis of the human organism. Many researchers proved the role of cortisol and its normal release rhythm in healthy individuals. It led to further investigations of the abnormalities in cortisol levels in those affected by various disorders , especially with neuropsychiatric symptoms. Autism spectrum disorder is one of these conditions which have been intensively researched due to its core and secondary symptoms. We conducted a systematic review of articles in PubMed, including papers that met the search criteria “autism” and “cortisol”. After initial selection of relevant papers, we analyzed data from 56 articles. We divided data into subcategories of studies concerning cortisol diurnal profile, basal cortisol levels, Cortisol Awakening Response (CAR) and cortisol levels in reaction to certain stimuli. Data was unequivocal, however, abnormal diurnal profile, basal level, CAR or stressor response were found in many research groups. It led to suspicion that the abnormalities of cortisol release are a widely-spread phenomenon among individuals with autism spectrum disorder. Very limited data from therapeutic interventions indicated more clinical than biological response. This systematic review should be a drive to action for further randomized clinical trial on larger, homogenous group of patients to obtain more thorough insight into the role of cortisol in autism spectrum disorder.
EN
Introduction. Cerebral Palsy (CP) is a neurological disorder caused by non-progressive damage to the central nervous system CNS in the perinatal or infantile period. The damage of the CNS causes progressive changes in the nervous control of the muscles and their structure. One theory of contracture development is satellite cells (SC) deficiency. SCs are muscle stem cells responsible for their growth, development and regeneration after an injury. The aim of this study is to present, based on a systematic review of the literature, the issue of SCs in a group of patients with CP.Material and methods. The systematic literature review was carried out according to PRISMA statement recommendations. MEDLINE/PubMed database was review using the key phrases: ‘satellite cells’ and ‘cerebral palsy’.Results. Between 2013 and 2021, 10 publications were identified, of which 3 were selected for detailed analysis. Significantly lower number of SCs was observed, also a reduced number of muscle fibers in the region for each SC, a smaller total number of muscle fibers, a reduction in the rate of fusion and myotubule formation in patients with CP.Conclusions. When planning a treatment and rehabilitation process, medical teams should take into account the reduced number of muscle SCs in patients with CP.
PL
Wstęp. Mózgowe porażenie dziecięce (MPD) jest zaburzeniem neurologicznym spowodowanym niepostępującym uszkodzeniem ośrodkowego układu nerwowego (OUN) w okresie okołoporodowym lub niemowlęcym. Uszkodzenie OUN nie ma charakteru progresywnego, natomiast powoduje postępujące zmiany zarówno w kontroli nerwowej mięśni, jak i w ich strukturze. Częstym powikłaniem tej niepogłębiającej się patologii OUN są przykurcze mięśniowe. Jedną z teorii wyjaśniającą powstawanie przykurczy jest ograniczona liczba komórek satelitarnych. Są to komórki macierzyste mięśni, odpowiadające za ich wzrost, rozwój i regenerację po urazie. Udowodniono, że u pacjentów z MPD w mięśniu przykurczonym jest o 60-70% mniej komórek satelitarnych niż w mięśniu osób zdrowych. Celem niniejszej pracy jest przedstawienie na podstawie systematycznego przeglądu piśmiennictwa zagadnienia dotyczącego komórek satelitarnych w grupie pacjentów z MPD. Materiał i metody. Przegląd piśmiennictwa został przeprowadzony zgodnie z rekomendacjami PRISMA Statement. Przeszukano medyczną bazę danych MEDLINE/PubMed z wykorzystaniem słów kluczowych: "komórki satelitarne" (ang. satellite cells) w połączeniu z "mózgowe porażenie dziecięce" (ang. cerebral palsy). Wyniki. W latach 2013-2021 zidentyfikowano 10 publikacji spełniających kryteria wyszukiwania, z tego 3 zakwalifikowano do szczegółowej analizy. Zanotowano znacznie mniejszą liczbę komórek satelitarnych w mięśniach, zmniejszoną liczbę włókien mięśniowych w obszarze dla każdej komórki satelitarnej, mniejszą łączną liczbę włókien mięśniowych, obniżenie szybkości tworzenia miotubuli u pacjentów z MPD w porównaniu do mięśni osób zdrowych. Wnioski. Planując proces leczenia i rehabilitacji, zespoły terapeutyczne powinny brać pod uwagę zredukowaną zawartość komórek satelitarnych w mięśniach pacjentów z MPD.
first rewind previous Page / 1 next fast forward last
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.