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Genetics of myocardial infarction in clinical practice. Is it ready for prime time?

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Notarangelo M. F., Bontardelli F., Giacalone R., Guidorossi A., Caporale V., Ardissino D.
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vol. 1
1-5
EN
Ischemic heart diseases are the leading cause of morbidity and mortality in developed countries, despite advances in cardiac care over the last few decades. Myocardial infarction is a complex, multifactorial disorder that is thought to be due to interactions between genetic and environmental factors. Recent rapid advances in molecular genetics techniques have identified a number of common genetic variants loosely associated with myocardial infarction, and highly promising, newly designed platforms should identify less common genetic variants with an even greater clinical impact. These discoveries have brought us to a stage at which we need to begin to consider how personalised genomic information should be incorporated into clinical practice in order to benefit individuals and society in general.
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