Search results

1

The relationship between the consumption of functional beverages and the use of other stimulants by high school students in Poland

100%

BŁASZCZYK E., PIÓRECKA B., JAGIELSKI P., PRUSAK A., SCHLEGEL-ZAWADZKA M.

Medicina Internacia Revuo

|

2015

|

vol. 26

|

issue 105

208-213

EN

Introduction: The results of national and international studies demonstrate the relationship of consumption of cola-type beverages by adolescents with increased dependence on other psychoactive substances, such as alcohol or tobacco. Aim: To assess the relationship between consumption of cola and functional drinks (energy and isotonic drinks) and other stimulants including coffee, tea, alcohol and cigarettes in a group of high school students. Material & methods: 120 students (16–17 years) attending upper secondary school in Lesko participated in the survey. The anonymous questionnaire collected data on frequency of consumption of selected products and beverages (FFQ), including functional beverages. To assess the differences between groups the Mann-Whitney U-test was appplied, while the relationship between variables was analyzed using the Spearman correlation coefficient (rs) at statistical significance level α=0.05. Results: The results showed that sugar beverages such as cola (soft drink), were consumed most frequently by young people (2.50±0.92). Of functional beverages, respondents choose energy drinks more often (2.07±0.87) than isotonic beverages (1.66±0.76). Among female respondents, a positive correlation between the consumption of energy drinks and cola drinks was found (rs=0.34, p=0.0001). Girls who smoke cigarettes reported consuming energy drinks significantly more often (p=0.0212) than non-smokers. The frequency of consumption of caffeinated beverages (cola and energizing drinks) in the surveyed group had no correlation with consumption of alcoholic beverages and tea. Conclusion: Excessive intake of caffeine by young people may lead to increased use of other stimulants. This indicates a need for quantitative data on consumption of caffeinated beverages by adolescents.

2

Caffeine and neurodegenerative disorders

100%

BOGATKO K., SZOPA A., POLESZAK E.

Medicina Internacia Revuo

|

2014

|

vol. 26

|

issue 103

89-93

EN

Neurodegenerative disorders are amongst the most dangerous diseases in modern society. At the end of 1990, adenosine receptor antagonists were used to block the adenosine A1 and A2A receptors causing less physical, cellular and molecular damage caused by Alzheimer’s and Parkinson’s diseases. In recent years, an increase in death rate caused by these diseases has been observed among people under 74. Caffeine, as NMDA receptor antagonist, prevents an uncontrolled influx of calcium ions into the interior of the cells exerting a neuroprotective effect and beneficial procognitive effects. There is much evidence that caffeine intake is associated with a reduced risk of Alzheimer’s and Parkinson’s diseases.

3

Review on analgesic effect of co-administrated ibuprofen and caffeine

100%

Polski A., Kasperek R., Sobotka-Polska K., Poleszak E.

Current Issues in Pharmacy and Medical Sciences

|

2014

|

vol. 27

|

issue 1

10-13

EN

Pain is a symptom of many diseases and significantly affects the quality of life, so researchers are constantly seeking new substances to be used as analgesics. Other, easier way is to combine already known drugs which cause synergistic effects greater than additive, so that probability of drug-specific side effects can be reduced. Researchers showed that caffeine can be an effective analgesic adjuvant enhancing antinociceptive effect of ibuprofen in animals and humans. By using modern drug technology methods tablets containing well-soluble ibuprofen salt and caffeine can be easily prepared. Thanks to that combination, the therapeutic dose of ibuprofen can be lowered and the side effects may be reduced.

4

Inhibition study of adenosine deaminase by caffeine using spectroscopy and isothermal titration calorimetry.

100%

Saboury A. A., Divsalar A., Ataie G., Amanlou M., Moosavi-Movahedi A. A., Hakimelahi G. H.

|

2003

|

vol. 50

|

issue 3

849-855

EN

Kinetic and thermodynamic studies were made on the effect of caffeine on the activity of adenosine deaminase in 50 mM sodium phosphate buffer, pH 7.5, using UV spectrophotometry and isothermal titration calorimetry (ITC). An uncompetitive inhibition was observed for caffeine. A graphical fitting method was used for determination of binding constant and enthalpy of inhibitor binding by using isothermal titration microcalorimetry data. The dissociation-binding constant is equal to 350 μM by the microcalorimetry method, which agrees well with the value of 342 μM for the inhibition constant that was obtained from the spectroscopy method. Positive dependence of caffeine binding on temperature indicates a hydrophobic interaction.

5

In vitro pharmacological interaction of caffeine and first-line antibiotics is antagonistic against clinically important bacterial pathogens

88%

Olajuyigbe O., Adeoye-Isijola M., Okon V., Adedayo O., Coopoosamy R.

|

2017

|

vol. 64

|

issue 2

255-263

EN

The in vitro antibacterial activity of pure caffeine powder and its interaction with first line antibiotic against bacterial isolates were investigated with the macrobroth dilution and the checkerboard assay methods. This study showed that caffeine and the antibiotics exhibited various degrees of antibacterial activities. While caffeine had MICs ranging between 67.19 and 268.75 µg/ml, chloramphenicol was characterized by MICs between 0.98 and 31.25 µg/ml, kanamycin - 15.63-62.5 µg/ml, nalidixic acid - 0.49-250 µg/ml, erythromycin - 0.49-62.5 µg/ml, tetracycline - 1.99-62.5 µg/ml and metronidazole - 15.63-31.25 µg/ml. Combining ½ MICs and MICs of caffeine with the antibiotics as well as direct combination of caffeine and the antibiotics resulted in significant reduction of antibiotics' effectiveness. The fractional inhibitory concentration index (FICI) for the combination of ½ MICs of caffeine with different antibiotics showed antagonistic interactions with the antibiotics except kanamycin which had additive and indifferent interactions with caffeine. The FICI of the MICs of caffeine combined with antibiotics showed a reduction in the number of antagonistic interactions as chloramphenicol, nalidixic acid and erythromycin showed some indifferent interactions while kanamycin was the only antibiotic that showed indifferent interaction against all the bacterial isolates. The direct combination of caffeine and the antibiotics resulted in significant antagonistic interactions higher than in the case when caffeine, at the ½ MICs and MICs, was combined with the antibiotics. Although caffeine demonstrated significant antibacterial activity against the selected bacterial isolates, its combination with the selected antibiotics resulted in significant antagonistic interactions. Caffeine should not be combined with antibiotics as this could result in serious therapeutic failure and, possibly, drug toxicity in vivo.

6

The Popular Ergogenic Substances in Sport and Physical Activity

88%

Świtała K.

Central European Journal of Sport Sciences and Medicine

|

2023

|

vol. 41

69-80

EN

Few supplements have a scientifically proven ergogenic effects of improving exercise capacity and/or physical performance in sport. The athletes require specialised nutrition, including precisely good quality supplementation, i.e. scientifically tested. Nowadays, more and more athletes use nutritional supplementation to improve their sporting performance both at the elite and non-elite levels. In this review, ergogenic substances such as the β-alanine, caffeine, creatine monohydrate, creatine malate, sodium bicarbonate were analysed among athletes/active people from an exercise and health capacity perspective. The aim of this review is to analyse the efficacy, mechanisms of action, dosage, side effects of the selected ergogenic substances, among athletes involved in physical effort/specific sport disciplines. Furthermore, the article will show the benefits of using these supplements in terms of health as well as improvement of exercise capacity among athletes.

7

Adsorption of penicillin by decaffeinated tea waste

88%

Gharbani P., Mehrizad A., Jafarpour I.

|

EN

Removal of penicillin has been investigated using decaffeinated tea waste (DCTW). Decaffeination of tea waste was investigated using different methods. Results indicate that ozonation was the most effective process for removal of penicillin. Batch adsorption experiments were completed at various temperatures (20, 30, and 40°C), DCTW dosages (2, 4, 6, 8, and 10 g per 250 mL), penicillin concentrations (4, 10, and 14 mg/L), and pH (3, 7, and 10) conditions. Studies showed that adsorption reaches equilibrium within 40 min. The main factor affecting adsorption of penicillin was the solution pH, with maximum adsorption occurring at pH 3. Higher adsorbent dosages and lower penicillin concentrations also resulted in higher percentages of penicillin removal. Results show that data obeyed the pseudo-first-order kinetic and Freundlich isotherm models. This process proves that low-cost DCTW could be used as a high performance adsorbent for removing penicillin from aqueous solutions.

8

Neurological effects of acute exposure to caffeine and organophosphates in mice

75%

Łukawski K., Raszewski G., Kruszyński K., Czuczwar S. J., Łukawski K., Raszewski G., Kruszyński K., Czuczwar S. J.

Polish Journal of Veterinary Sciences

|

2021

|

vol. 24

|

issue 2

9

Caffeine degradation in water by gamma irradiation, ozonation and ozonation/gamma irradiation

75%

Torun M., Abbasova D., Şolpan D., Güven O.

|

EN

Aqueous solutions of caffeine were treated with ozone and gamma irradiation. The amounts of remaining caffeine were determined after solid phase extraction as a function of absorbed dose and ozonation time. In addition to this, some important parameters such as inorganic ions, chemical oxygen demand (COD) dissolved oxygen and total acidity changes were followed. Caffeine (50 ppm) is found to be completely decomposed at 3.0 kGy and 1.2 kGy doses in the absence of H2O2 and in 1.20 mM H2O2 solutions, respectively. In the case of gamma irradiation after ozonation, 50 ppm caffeine was removed at 0.2 kGy when the solution was ozonized for 100 s at a rate of 10 g O3 h-1 in 400 mL 50 ppm paracetamol solution.

10

Występowanie cech kofeinizmu u młodzieży i młodych dorosłych deklarujących częste spożycie bezalkoholowych napojów typu cola zawierających kofeinę

63%

Gustek S., Barcz M., Jaworski M.

Pediatria i Medycyna Rodzinna

|

2011

|

vol. 7

|

issue 4

366-371

EN

Introduction: Over the past few years there has been a significant increase in consumption of caffeinated beverages, especially among children and adolescents. This trend is worrisome, and numerous studies point to the negative impact of excess supply of caffeine on various aspects of human functioning. In order to analyse this problem a proper study was conducted which aim was to assess the problem of addiction to caffeine among adolescents and young adults with particular emphasis on the characteristics of people declaring frequent consumption of soft beverages. Material and methods: Based on the review of literature about caffeinism authors constructed a questionnaire survey and identified the following inclusion criteria: 1) declaration of consuming soft beverages, 2) age 13-30 years. Diagnostic survey was conducted on a group of 118 people. Demographic variables were also controlled. Results: The most frequently declared potential symptoms of caffeinism were: headache, irritability and explosiveness, sleep problems, insomnia, palpitations and accelerated heartbeat, but these results differed within age groups. Conclusions: Excessive intake of soda products and exposure to high doses of caffeine can be an important environmental factor in the formation and maintezawierająnance of chronic diseases and addictions, also can be associated with poor dietary behaviours. Therefore it is important to prevent and rise awareness of children, adolescents and their parents about the dangers of excessive supply of products containing caffeine as well as further research on the effects of caffeine on the psychophysical functioning in this age group.

PL

Wprowadzenie: W ciągu ostatnich lat obserwuje się znaczny wzrost spożycia napojów zawierających kofeinę, szczególnie wśród dzieci i młodzieży. Tendencja ta jest niepokojąca, a liczne badania wskazują na negatywny wpływ nadmiernej podaży kofeiny na różne aspekty funkcjonowania człowieka. W celu głębszej analizy tego zjawiska przeprowadzono badanie własne i dokonano próby oceny problemu uzależnienia od kofeiny wśród młodzieży i młodych dorosłych ze szczególnym uwzględnieniem cech kofeinizmu u osób deklarujących częste spożycie napojów typu cola. Materiał i metodyka: Na podstawie przeglądu literatury dotyczącej kofeinizmu skonstruowano autorski kwestionariusz ankiety. Określono następujące kryteria włączenia do badania: 1) deklaracja o spożywaniu napojów typu coca-cola, 2) wiek 13-30 lat. W badaniu metodą sondażu diagnostycznego wzięło udział 118 osób. Dodatkowo kontrolowano także zmienne demograficzne, tj. wiek, płeć oraz wzrost i masę ciała. Wyniki: Najczęściej deklarowane przez respondentów potencjalne objawy kofeinizmu to: bóle głowy, drażliwość i wybuchowość, problemy ze snem, przyspieszona praca serca i palpitacje, przy czym symptomy te uzależnione były od wieku. Wnioski: Nadmierne spożycie produktów zawierających kofeinę może być ważnym czynnikiem środowiskowym w kształtowaniu i utrzymywaniu się chorób przewlekłych oraz uzależnień, a także wiązać się ze złymi zachowaniami żywieniowymi. Dlatego tak istotne są profilaktyka i zwiększanie świadomości dzieci, młodzieży oraz ich rodziców na temat szkodliwości nadmiernej podaży produktów zawierających kofeinę, a także dalsze badania nad wpływem kofeiny na funkcjonowanie psychofizyczne tej grupy wiekowej.

Refine search results

The relationship between the consumption of functional beverages and the use of other stimulants by high school students in Poland

Caffeine and neurodegenerative disorders

Review on analgesic effect of co-administrated ibuprofen and caffeine

Inhibition study of adenosine deaminase by caffeine using spectroscopy and isothermal titration calorimetry.

In vitro pharmacological interaction of caffeine and first-line antibiotics is antagonistic against clinically important bacterial pathogens

The Popular Ergogenic Substances in Sport and Physical Activity

Adsorption of penicillin by decaffeinated tea waste

Neurological effects of acute exposure to caffeine and organophosphates in mice

Caffeine degradation in water by gamma irradiation, ozonation and ozonation/gamma irradiation

Występowanie cech kofeinizmu u młodzieży i młodych dorosłych deklarujących częste spożycie bezalkoholowych napojów typu cola zawierających kofeinę