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EN
The paper presents a case of Burkitt lymphoma manifested by bleeding from a gastric ulcer. The control of bleeding required the use of diagnostic and therapeutic methods of interventional radiology.
EN
Hemorrhoid is protrusion of plexus or blood vessels in the anal canal. The hemorrhoid may cause symptoms that are: bleeding, pain, prolaps, itching, soilage of feces, and psychologic discomfort. There are many methods for treatment of hemorrhoid like, medical therapy, cryo-therapy, rubber band ligation, sclerotherapy, laser, and surgery. All methods have some complication in postoperative period and recurrence.The aim of the study was to evaluate Diode laser for treatment of hemorrhoid.Material and methods. This study included patients who suffer from the hemorrhoid. Cases with fistula and fissure had been omitted. Patients with hemorrhoid in grade 2, 3, 4 and mixed were treated with diode laser. Follow up was done 1,7,14, 30, 90, and 360 days laser therapy.Results. In this study, 341 patients with hemorrhoid treated with diode laser were included. Results of follow-up were as follows: need for analgesia in hospital stay and home was very low total complication was seen in 12 patient (3.51%), edema in 8 patient (2.34%), hemorrhage and abscess each of them in 2 patient (0.58%), stricture and recurrence was zero after one year.Conclusions. All methods used for hemorrhoid treatment has advantages, disadvantages, and limitations. But treatment of hemorrhoid by Diode laser, which is done by skilled surgeon has several advantages over other treatments. This advantages include, less operation time, less pain and bleeding, allow quick healing of piles, no stricture, and minimal recurrence after operation.
EN
A 77-year-old female patient was presented to the emergency department with swelling and bleeding in the occiput. It was learned from the patient that the soft tissue swelling on her head had been present for 1 year, and she had no history of trauma. The patient had diabetes mellitus and hypertension and a history of breast cancer 15 years ago. An epidermoid cyst, approximately 5x5 centimeter in size, bleeding in the form of leakage was observed on the patient's occipital scalp. There was no intracranial pathology in the brain computerized tomography. Wound debridement revealed that the cyst contained approximately 30 live larvae. All larvae were cleaned from the tissue defect. When looking from the outside, the larvae were 8-12 millimeters in size, yellow-white, spiral in shape, and were thought to be compatible with the larva of Lucilia sericata diptera. Myiasis is an ectoparasitic infection of diptera larvae by settling in human and animal tissues. When flies leave their larvae in the tissue, the larvae that invade and develop in that area cause infection. Cutaneous myiasis is the most common clinical form and can be seen on the scalp and cause furuncular myiasis. Immunosuppression, lack of self-care, travel to endemic areas and trauma have been reported as risk factors for myiasis. It was thought that the history of diabetes and old malignancy might be predisposing in our patient. In this case report, it is aimed to present a case of furuncular myiasis that settled down without any trauma to the occiput and presented with spontaneous soft tissue bleeding.
PL
77-letnia pacjentka została przyjęta na oddział ratunkowy z obrzękiem i krwawieniem potylicy. Od pacjentki dowiedzino się, że obrzęk tkanek miękkich na głowie występował od 1 roku i nie miała urazu w wywiadzie. Pacjentka miała cukrzycę i nadciśnienie tętnicze oraz raka piersi w wywiadzie 15 lat temu. Na skórze głowy potylicznej pacjentki stwierdzono torbiel naskórkową o wymiarach około 5x5 cm, krwawiącą w postaci wycieku. W tomografii komputerowej mózgu nie stwierdzono patologii wewnątrzczaszkowej. Oczyszczenie rany wykazało, że cysta zawierała około 30 żywych larw. Wszystkie larwy oczyszczono z ubytku tkanki. Patrząc z zewnątrz, larwy miały rozmiar 8-12 milimetrów, były żółto-białe, spiralnie ukształtowane i uważano, że są kompatybilne z larwami Lucilia sericata diptera. Muszyca to ektopasożytnicze zarażenie larw muchówek poprzez zasiedlenie tkanek ludzkich i zwierzęcych. Kiedy muchy pozostawiają swoje larwy w tkance, larwy, które atakują i rozwijają się w tym obszarze, powodują infekcję. Muszyca skórna jest najczęstszą postacią kliniczną i może być widoczna na skórze głowy i powodować muszycę czyrakową. Immunosupresja, brak samoopieki, podróże do obszarów endemicznych i urazy zostały zgłoszone jako czynniki ryzyka muszycy. Uznano, że u opisywanej pacjentki predysponować może przebyta cukrzyca i przebyta choroba nowotworowa. Celem niniejszego opisu przypadku jest przedstawienie przypadku muszycy czyrakowej, która ustąpiła bez urazu potylicy i objawiła się samoistnym krwawieniem do tkanek miękkich.
EN
Introduction: Bleeding from esophageal varices is a serious clinical condition in hemophilia patients due to congenital deficiency or lack of clotting factors VIII (in hemophilia A) and IX (in hemophilia B), decreased clotting factor II, VII, IX, X synthesis in the course of chronic liver disease and hipersplenic thrombocytopenia. The aim of this study was to assess the efficacy and safety of endoscopic sclerotherapy in acute esophageal variceal bleeding and in secondary prophylaxis of hemorrhage. The aim was also to investigate the optimal activity of deficiency factors VIII or IX and duration of replacement therapy required to ensure proper hemostasis after sclerotherapy procedures. Material and methods: 22 hemophilia patients (A-19, B-4) with coexistent liver cirrhosis and active esophageal variceal bleeding treated with endoscopic sclerotherapy were subjected to prospective analysis. The patients who survived were qualified to repeated sclerotherapy procedures every 3 weeks within secondary prophylaxis of bleeding (investigated group). A 3-day substitution therapy enhanced the infusion of the deficient or lacking factor in doses allowing to reach 80-100% of normal value activity of factor VIII on the 1st day and 60-80% in the next two days. The desired activity of factor IX was 60-80% and 40-60% respectively. The control group consisted of 20 non-hemophiliac patients with liver cirrhosis comparable in terms of age, sex, stage of advancement of liver cirrhosis, who underwent the same medical proceedings as the investigated group. Results: Active esophageal bleeding was stopped in 21 of 22 (95%) hemophilia patients. Complications were observed in 3 patients; 2 patients died. The rate of hemostasis, complications and deaths in the control group were comparable and no statistical differences were found. In hemophilia patients subjected to secondary prophylaxis of hemorrhage, in 18 of 20 (80%), complete eradication of esophageal varices was achieved after 4 to 7 sclerotherapy procedures in 1 patient (average 5.4). Recurrent bleeding was observed in 15% of patients, complication in 20%; 1 patient died. Time lapse from bleeding to eradication was 12-21 weeks (average 15.2). In the control group the rate of variceal eradication, complication and deaths was comparable and no statistical differences were found. The usage of factor VIII concentrates was as follows: in hemophilia A, in a severe form - 80.9 U/kg b.w./day, in hemophilia A in a severe form with an inhibitor <5 BU – 95.2 U/kg b.w./day, in mild form – 64.2 U/kg b.w./day and in severe hemophilia B – 91.6 U/kg b.w./day. Conclusions: Sclerotherapy is an effective method in the management of esophageal variceal bleeding in hemophilia patients. It is also effective for total eradication of varices when applied as a secondary prophylaxis of hemorrhage. In our opinion, a 3-day replacement therapy at the applied doses is sufficient to ensure hemostasis and avoid bleeding complications.
EN
Intraabdominal hemorrhage remains one of the most frequent surgical complications after liver transplantation. The aim of the study was to evaluate risk factors for intraabdominal bleeding requiring reoperation and to assess the relevance of the reoperations with respect to short- and long-term outcomes following liver transplantation. Material and methods. Data of 603 liver transplantations performed in the Department of General, Transplant and Liver Surgery in the period between January 2011 and September 2014 were analyzed retrospectively. Study end-points comprised: reoperation due to bleeding and death during the first 90 postoperative days and between 90 postoperative day and third post-transplant year. Results. Reoperations for intraabdominal bleeding were performed after 45 out of 603 (7.5%) transplantations. Low pre-transplant hemoglobin was the only independent predictor of reoperation (p=0.002) with the cut-off of 11.3 g/dl. Postoperative 90-day mortality was significantly higher in patients undergoing reoperation as compared to the remaining patients (15.6% vs 5.6%, p=0.008). Post-transplant survival from 90 days to 3 years was non-significantly lower in patients after reoperation for bleeding (83.3%) as compared to the remaining patients (92.2%, p=0.096). Nevertheless, multivariable analyses did not reveal any significant negative impact of reoperations for bleeding on short-term mortality (p=0.589) and 3-year survival (p=0.079). Conclusions. Surgical interventions due to postoperative intraabdominal hemorrhage do not appear to affect short- and long-term outcomes following liver transplantation. Preoperative hemoglobin concentration over 11.3 g/dl is associated with decreased risk of this complication, yet the clinical relevance of this phenomenon is doubtful.
EN
Some patients who need dual antiplatelet therapy sometimes require tracheotomy. Aim of this study was to compare the rate of complications during and after surgical tracheotomy between patients requiring dual antiplatelet therapy and those without dual antiplatelet therapy. We retrospectively included 79 patients (62% men, mean age 64 ± 14 years) in the period 2007- 2011. The following complications were analyzed: need for surgical revision within 24 hours after tracheotomy, need for bronchoscopy within 24 hour after tracheotomy, need for blood transfusion within 24 hours after tracheotomy, death attributed to tracheotomy and any complication attributed to tracheotomy. We compared patients where tracheotomy was performed while receiving dual antiplatelet therapy (n=27, 34%) to patients where tracheotomy was performed without dual antiplatelet therapy (n=52, 66%). Nonsignificant differences between the two groups were observed general characteristics. There were no statistically significant differences in complications after tracheotomy (surgical revision after tracheotomy p=0.63, bronchoscopy after tracheotomy p=0.74, blood transfusion after tracheotomy p=0.59, death attributed to tracheotomy p=1.00 and any complication attributed to tracheotomy p=1.00). The study shows that tracheotomy is safe in cardiac patients on dual antiplatelet therapy.
EN
Chitosan are biopolymers that are actively used for the production of local haemostatic agents. The physicochemical characteristics that determine its biological properties include the molecular weight and the deacetylation degree. However, there is no linear relationship between these parameters and haemostatic activity. The most reliable method of confirming the effectiveness is still in vivo experiments. The ability to initiate haemostasis depends on the conformational transition of chitosan macromolecules. The highest efficiency in vitro was for samples in which the transition of a significant part of the molecules from the ‘rigid rod’ state to the ‘globule’ occurred at physiological pH. It is proposed to expand the list of indicators of chitosan that can be controlled to evaluate the quality of raw materials, related to haemostatic activity, to include the definition of the conformational transition at physiological pH.
EN
ESWL (extracorporeal shock wave lithotripsy) is one of the basic treatment methods of the renal calculosis which is widely used as a non-invasive and efficient technique. With the growth of experience of the urologists who are performing lithotripsy treatments and improvement of lithotriptors, effectiveness of the medical procedures is rising. The authors report the extremely rare complication after the ESWL treatment as a kidney rupture and massive bleeding in the retroperitoneal space. A 78-year-old patient with thrombocytopenia after CABG, after implantation of the pacemaker, with hypertension and type II diabetes, treated with oral anticoagulants, was urgently admitted to the Clinic of Urology 6 hours after the ESWL treatment because of deterioration of general condition, increasing pains in the left lumbar region and massive haematuria. The kidney rupture with massive haematoma of the retroperitoneal space was diagnosed after the subjective and objective examination and on the bases of the additional tests (computer tomography of the abdomen). The patient was immediately qualified to the operative treatment. Huge haematoma filling the space of the left kidney and heading for the left iliac fossa as well as massive bleeding from a whole surface of the left injured kidney without possibilities of reaching haemostasia, was intraoperatively diagnosed. Regarding the above clinical picture a decision on resection of the left kidney was taken. With regard to massive posthaemorrhagic changes in surrounding tissues and uncertainty considering haemostasia, packing was carried out – 6 napkins were put into the retroperitoneal space. No complications occurred in the early postoperative period. The patient showed proper parameters of circulatory, respiratory and renal excretion efficiency. According to plan the napkins were removed from the left retroperitoneal space on the third day after the treatment. The renal bed after the kidney resection shows no pathologic changes. The patient was discharged from hospital after 16 days in good general condition.
PL
Kruszenie kamieni falą generowaną pozaustrojowo (extracorporeal shock wave lithotripsy, ESWL) należy do podstawowych metod leczenia kamicy nerkowej – zyskała ona szerokie zastosowanie jako metoda małoinwazyjna i skuteczna. Wraz ze wzrostem doświadczenia urologów wykonujących zabiegi litotrypsji oraz udoskonalaniem litotryptorów wzrasta skuteczność wykonywanych zabiegów. Autorzy przedstawiają niezmiernie rzadkie powikłanie po zabiegu ESWL pod postacią pęknięcia nerki i masywnego krwawienia do przestrzeni zaotrzewnowej. Siedemdziesięcioośmioletni pacjent z małopłytkowością, po zabiegu by-passów (coronary artery bypass graft, CABG), po implantacji układu stymulującego serca, z nadciśnieniem tętniczym i cukrzycą typu II, leczony doustnymi antykoagulantami został przyjęty do Kliniki Urologicznej 6 godzin po zabiegu ESWL w trybie pilnym z powodu pogarszającego się stanu ogólnego, narastających dolegliwości bólowych w lewej okolicy lędźwiowej i masywnego krwiomoczu. Po przeprowadzeniu badania podmiotowego, przedmiotowego i na podstawie wykonanych badań dodatkowych (tomografia komputerowa jamy brzusznej) rozpoznano pęknięcie nerki z masywnym krwiakiem przestrzeni zaotrzewnowej. Chorego zakwalifikowano w trybie pilnym do leczenia operacyjnego. Śródoperacyjnie stwierdzono ogromny krwiak wypełniający przestrzeń zaotrzewnową wokół nerki lewej i schodzący do lewego dołu biodrowego oraz masywne krwawienie z całej powierzchni uszkodzonej nerki bez możliwości opanowania krwawienia. Wobec powyższego obrazu podjęto decyzję o wycięciu nerki lewej. Z uwagi na stwierdzone płaszczyznowe krwawienie w otaczających tkankach i brak pewności co do ostatecznej hemostazy zdecydowano wykonać packing – założono 6 serwet do przestrzeni zaotrzewnowej. We wczesnym okresie pooperacyjnym nie stwierdzono powikłań. Pacjent krążeniowo, oddechowo i nerkowo wydolny. W 3. dobie od zabiegu w trybie planowym usunięto serwety z lewej przestrzeni zaotrzewnowej, nie stwierdzając krwawienia w loży po usuniętej nerce. Pacjent w 16. dobie hospitalizacji wypisany do domu w stanie ogólnym dobrym.
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