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EN
Background Cystic fibrosis(CF),despite much progress in therapy, remains the disease which affects nutrition. Nutrition is an important prognostic factor of the outcome of the disease. We want to evaluate physical development, nutrition and body composition in CF children. Material and methods 75 children diagnosed with CF (9 months to 18 years old) were included into the study. 33 healthy children (9 months to 18 years old) constituted the control group. The study consisted of 2 stages. In the first the differences between groups were investigated. The second, took place a year later. At each time point the following measurements were performed: height, body mass, skin fold, arm circumference; BMI, FFM%, FM% and Frisancho index. FFM(fat free mass), FM(fat mass), muscle mass, TBW(total body water) were evaluated by mans of BIA(bioimpedance). Results CF children were shorter than healthy children. Stunting affected 18,67% of CF patients at first examination and 21,6% a year later. Underweight was diagnosed in 28% of patients at the beginning and in 41.2% a year after. Underweight was the result of both little FM and scarce muscle mass. Conclusions Many children with cystic fibrosis suffers from short stature and underweight, which progresses within time. FFM decreases with the disease progress
EN
Background: Cystic fibrosis(CF),despite much progress in therapy, remains the disease which affects nutrition. Nutrition is an important prognostic factor of the outcome of the disease. We want to evaluate physical development, nutrition and body composition in CF children. Material and methods: 75 children diagnosed with CF (9 months to 18 years old) were included into the study. 33 healthy children (9 months to 18 years old) constituted the control group. The study consisted of 2 stages. In the first the differences between groups were investigated. The second, took place a year later. At each time point the following measurements were performed: height, body mass, skin fold, arm circumference; BMI, FFM%, FM% and Frisancho index. FFM(fat free mass), FM(fat mass), muscle mass, TBW(total body water) were evaluated by mans of BIA(bioimpedance). Results: CF children were shorter than healthy children. Stunting affected 18,67% of CF patients at first examination and 21,6% a year later. Underweight was diagnosed in 28% of patients at the beginning and in 41.2% a year after. Underweight was the result of both little FM and scarce muscle mass. Conclusions: Many children with cystic fibrosis suffers from short stature and underweight, which progresses within time. FFM decreases with the disease progress
EN
WSTĘP: Do określenia tzw. suchej masy ciała zastosowano metodę bioimpedancji elektrycznej (BIA). Głównym celem pracy była ocena przydatności oznaczania suchej masy ciała za pomocą bioimpedancji elektrycznej u przewlekle dializowanych dzieci i młodych dorosłych, w tym w szczególności w odniesieniu do wybranych wykładników biochemicznych i parametrów układu sercowo-naczyniowego. Dodatkowo w tej grupie pacjentów, przy użyciu BIA, analizowano stan odżywienia. MATERIAŁ I METODY: Badaniem objęto 17 dzieci i młodych dorosłych w wieku od 6 do 24 lat (średnio 15 ± 3,5 roku), leczonych przewlekle hemodializą lub dializą otrzewnową. Oceniono wartości ciśnienia tętniczego, badania biochemiczne, parametry sercowe i wyniki z bioimpedancji w badaniu wyjściowym i po 2 miesiącach, po modyfikacji leczenia dializacyjnego w oparciu o parametry BIA. WYNIKI: Badane parametry ciśnienia tętniczego (skurczowe, rozkurczowe, średnie, tętna) było istotnie niższe podczas drugiego badania w porównaniu z wartościami wyjściowymi. Stężenie hemoglobiny było istotnie wyższe po 2 miesiącach obserwacji. W badaniu echokardiograficznym wykazano istotny wzrost frakcji wyrzutowej lewej komory, przy niezmienionych parametrach anatomicznych serca. Oceniane wskaźniki odżywienia – tkanki beztłuszczowej (LTI) i tłuszczowej (FTI) – nie uległy zmianie. Wykazano dodatnią korelację LTI z ciśnieniem tętniczym i niektórymi para-metrami z badania echokardiograficznego. WNIOSKI: Bioimpedancja elektryczna, jako prosta do przeprowadzenia i nieinwazyjna metoda, może być przydatna do precyzyjnego wyznaczania tzw. suchej masy ciała u dializowanych dzieci i młodych dorosłych. Adekwatne odwodnienie pacjentów pozwala na normalizację ciśnienia tętniczego krwi, co wiąże się z poprawą funkcji i prawdopodobnie stanu anatomicznego mięśnia sercowego. BIA pozwala także na dokładniejszą ocenę stanu odżywienia dializowanych chorych i wcześniejsze wykrycie niedożywienia, co w przypadku populacji pediatrycznej ma znaczenie rokownicze.
PL
INTRODUCTION: Electrical bioimpedance (BIA) is used to estimate a patient's dry weight. The main goal of the study was to assess the usefulness of BIA in evaluating dry weight in children and young adults on chronic dialysis, with relation to selected biochemical and cardiovascular parameters. An additional goal was to analyze the state of nutrition by means of BIA. MATERIAL AND METHODS: 17 children and young adults, aged from 6 to 24 years (mean 15 ± 3.5 years) on hemodialysis or peritoneal dialysis, were examined. We estimated the arterial blood pressure, biochemical results, echocardiographic and bioimpedance parameters during the initial examination. Based on these results, modifications in the dialysis treatment were introduced. The follow-up examination was performed after 2 months. RESULTS: Arterial blood pressure values were significantly lower at the time of the second examination compared to the first one. The hemoglobin levels were higher after 2 months of observation. In the echocardiographic results, only the EF% improved. The Lin Tissue Indexes (LTI) and the Fat Tissue Indexes (FTI) were similar in both examinations. We observed positive correlations between LTI and arterial blood pressure and some echocardiographic parameters. CONCLUSION: The arterial blood pressure values were significantly lower at the time of the second examination compared to the first one. The hemoglobin levels were higher after 2 months of observation. In the echocardiographic results, only the EF% improved. The Lin Tissue Indexes (LTI) and the Fat Tissue Indexes (FTI) were similar in both examinations. We observed positive correlations between LTI and arterial blood pressure and some echocardiographic parameters.
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