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Carotenoid composition and in vitro pharmacological activity of rose hips

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Horváth G., Molnár P., Radó-Turcsi E., Deli J., Kawase M., Satoh K., Tanaka T., Tani S., Sakagami H., Gyémánt N., Molnár J.
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2012
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vol. 59
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issue 1
129-132
EN
The aim of the present study was to compare carotenoid extracts of Rose hips (Rosa canina L.) with regard to their phytochemical profiles and their in vitro anti-Helicobacter pylori (H. pylori), cytotoxic, multidrug resistance (MDR) reversal and radical scavenging activity. Carotenoid composition was investigated in the different fractionation of rose hips, using extraction methods. Six main carotenoids - epimers of neochrome, lutein, zeaxanthin, rubixanthin, lycopene, β,β-carotene - were identified from Rose hips by their chromatographic behavior and UV-visible spectra, which is in accordance with other studies on carotenoids in this plant material. The active principles in the carotenoid extract might differ, depending upon the extraction procedures.
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