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Multiple sclerosis (MS) is a disease of the central nervous system that results in many symptoms including mobility limitation, fatigue and redacted quality of life.The purpose of this study was to determine the effect of a yoga intervention on balance, speed and endurance of walking, fatigue and quality of life in MS patients.21women with MS (34.38±5,68) with Expanded Disability Status Scale scores 1.0 to 4.0, have been randomly assigned to a yoga group or control group. Yoga group subjects participated in a thrice weekly 60-70 minute sessions of Hatha yoga intervention for 8-weeks. Balance, speed and endurance of walking, fatigue and quality of life were measured by Berg Balance scores; 10-m time and 2-minute distance walking, Fatigue Severity Scale (FFS) and Multiple Sclerosis Quality of Life-54 questionnaire (MSQOL-54) respectively.Comparison of results of pre and post intervention revealed significant improvement on balance score, walking endurance, FFS and some of MSQOL-54 scale scores in the yoga group (p≤0.05 respectively). There were no clear changes in10-m times (p= 0.132), related to yoga group. No changes were observed for control group.These results suggest that yoga intervention can be beneficial for patients with MS
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