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EN
The paper presents results of experimental studies on removal of NOx from flue gas via NO ozonation and wet scrubbing of products of NO oxidation in NaOH solutions. The experiment was conducted in a pilot plant installation supplied with flue gas from a coal-fired boiler at the flow rate 200 m3/h. The initial mole fraction of NOx,ref in flue gas was approx. 220 ppm, the molar ratio X = O3/NOref varied between 0 and 2.5. Ozone (O3 content 1÷5% in oxygen) was injected into the flue gas channel before the wet scrubber. The effect of the mole ratio X, the NaOH concentration in the absorbent, the liquid-to-gas ratio (L/G) and the initial NOx concentration on the efficiency of NOx removal was examined. Two domains of the molar ratio X were distinguished in which denitrification was governed by different mechanisms: for X ≤ 1.0 oxidation of NO to NO2 predominates with slow absorption of NO2, for X >> 1.0 NO2 undergoes further oxidation to higher oxides being efficiently absorbed in the scrubber. At the stoichiometric conditions (X = 1) the effectiveness of NO oxidation was better than 90%. However, the effectiveness of NOx removal reached only 25%. When ozonation was intensified (X ≥ 2.25) about 95% of NOx was removed from flue gas. The concentration of sodium hydroxide in the aqueous solution and the liquid-to-gas ratio in the absorber had little effect on the effectiveness of NOx removal for X > 2.
EN
According to the European Society of Cardiology (ESC) guidelines, non-vitamin K antagonist oral anticoagulants (NOACs) are first choice drugs in prevention of thromboembolic events among patients with atrial fibrillation (AF). According to our knowledge this was the only case of delayed absorption of dabigatran due to ileus. A 79-year-old woman with hypertension and a 1-year history of persistent AF treated with dabigatran (a direct thrombin inhibitor approved for the prevention of stroke in patients with non-valvular AF) 110 mg bid for two weeks. She was hospitalized due to acute abdominal pain, vomiting and diarrhea. Signs of acute embolism of abdominal aorta (paraparesis) were confirmed on contrast-enhanced computed tomography scan and she was qualified for emergency surgery. The use of idarucizumab, the specific reversal agent for dabigatran, was considered twice. This case shows that exposure to dabigatran may occur later in patient with acute ileus due to alterations in absorption than it can be expected in normal situation. Such patients should be carefully monitored for a significant rebound in anticoagulant activity.
EN
In this paper, we investigated the transient electron population and the transient behaviour of the dispersion, absorption and refractive property of weak probe light in a four-level InGaN/GaN quantum dot nanostructure. In order to achieve the wave functions and their corresponding energy levels of the mentioned quantum dot nanostructure, the Schrödinger and Poisson equations is solved selfconsistently for carriers (here electron) in quantum dot. Our findings show that the properties of transient processes can be dramatically affected by parameters such as intensity, detuning and relative phase of applied fields. Our proposed scheme provides a realistic model for transient control of refraction index properties in a quantum dot nanostructure. These results may have potential applications in high speed optical switch for quantum information technologies.
EN
Combinations of polymers and biopolymers of biologically active compounds in the last period have been the subject of intensive research. The active substance linked to a polymer often has a modified function and sometimes no action. On the other hand, the use of unsuitable polymers may result in a type of mismatch of drug-polymer. The aim of the study was to examine whether the active substance ketoconazole causes incompatibility with dietary supplements containing chitosan. Antifungal drug adsorption phenomenon was investigated by the static method in the concentration range of the single dose using a pharmaceutical model of the gastrointestinal tract. The test results show that the antifungal agent is adsorbed onto the chitosan in the pH ranges used, and the binding ability of the chitosan depends on the variety, or indirectly from the reaction environment. It was observed that the average sorption, depending on the variety of chitosan, was located in the limit from 94% to 100%. The increase of the size of the adsorption of anti-inflammatory drugs on the polymer with increasing pH from 7.6 to 8.0 can be explained by the swelling properties of chitosan, which grow with increasing pH of the environment in the direction of alkaline pH. Thus, the specific surface area and polymer sorption capacity is increased. Based on the above considerations, it can be concluded that, between the test drug and the polymer, there is antagonistic interaction involving the adsorption of the drug of this group on a polymer which is chitosan.
EN
According to the European Society of Cardiology (ESC) guidelines, non-vitamin K antagonist oral anticoagulants (NOACs) are first choice drugs in prevention of thromboembolic events among patients with atrial fibrillation (AF). According to our knowledge this was the only case of delayed absorption of dabigatran due to ileus. A 79-year-old woman with hypertension and a 1-year history of persistent AF treated with dabigatran (a direct thrombin inhibitor approved for the prevention of stroke in patients with non-valvular AF) 110 mg bid for two weeks. She was hospitalized due to acute abdominal pain, vomiting and diarrhea. Signs of acute embolism of abdominal aorta (paraparesis) were confirmed on contrast-enhanced computed tomography scan and she was qualified for emergency surgery. The use of idarucizumab, the specific reversal agent for dabigatran, was considered twice. This case shows that exposure to dabigatran may occur later in patient with acute ileus due to alterations in absorption than it can be expected in normal situation. Such patients should be carefully monitored for a significant rebound in anticoagulant activity.
EN
Background & Aims: Green tea is known worldwide for its high content of polyphenolic compounds and multifactorial beneficial effects on human health. The role of green tea as an inhibitor of lipid hydrolysis is widely discussed. The aim of the study was to assess the influence of green tea extract on lipid digestion and absorption. Methods: The study comprised 32 healthy volunteers aged 23 to 30 years with normal exocrine pancreatic function. In all subjects 13C-labelled mixed triglyceride breath test was performed twice with and without green tea extract ingestion. Cumulative percentage dose recovery was considered to reflect digestion and absorption of lipids. Values are expressed as medians and 1st-3rd quartile distribution. Results: In all subjects, cumulative percentage dose recovery values were normal in a placebo test (36.8% <30.1-43.3%>). These results were significantly higher (p=0.021) than those obtained in green tea extract test (28.8% <23.1-37.2%>). Results of six tests with GTE were abnormal. Conclusions: Single dose of green tea extract taken with a test meal decreases lipid digestion and absorption in humans.
Open Physics
|
2010
|
vol. 8
|
issue 1
95-100
EN
In practically all known methods of nuclear chronometry until now, research has usually taken into account the life-times of only the fundamental states of α-radioactive nuclei. But in the processes of nuclear synthesis in stars and under the influence of constant cosmic radiation on the surfaces of planets the excitations of the α-radioactive nuclei are still ongoing. Between these processes there are states with excited α-particles inside the parent nuclei leading to much smaller life-times. And inside the large masses of stellar, terrestrial and meteoric substances there are transitions between different internal conditions of radioactive nuclei that are accompanied by infinite chains of γ-radiations with subsequent γ-absorptions, further γ-radiations, etc. For a description of the α-decay evolution that accounts for such excited states and multiple γ-radiations and γ-absorptions inside stars, and under the influence of cosmic radiation on the Earth’s surface we present a quantum-mechanical approach, which is based on the generalized Krylov-Fock theorem. A few simple estimations are also presented. These approaches lead to the conclusion that the usual (non-corrected) “nuclear clocks” do really point not to realistic values but to the upper limits of the durations of α-decay in stellar and planet processes.
EN
Measurements of the absorption rate of carbon dioxide into aqueous solutions of N-methyldiethanoloamine (MDEA) and 2-ethylaminoethanol (EAE) have been carried out. On this basis a mathematical model of the performance of an absorption column operated with aqueous solution of a blend of the above amines at elevated temperatures and pressures have been proposed. The results of simulations obtained by means of this model are described. The work is a part of a wider program, aimed at the development of a new process.
EN
The goal of this work was to investigate the spectroscopic properties of Pr3+ ions, embedded in two different tellurite glass matrices, TeO2-WO3-PbO-La2O3 and TeO2-WO3-PbO-Lu2O3. The absorption and fluorescence spectra have been recorded and analyzed in terms of the Judd-Ofelt theory along with the luminescence decay of the 3P0 and 1D2 levels of the Pr3+ ion. The spectroscopic studies were completed with ellipsometric measurements providing the dispersion relation of the refractive index of the investigated glasses.
Open Physics
|
2012
|
vol. 10
|
issue 2
478-484
EN
Un-doped and Mn-doped ZnO nanoparticles were successfully synthesized in an ethanolic solution by using a sol-gel method. Material properties of the samples dependence on preparation conditions and Mn concentrations were investigated while other parameters were controlled to ensure reproducibility. It was observed that the structural properties, particle size, band gap, photoluminescence intensity and wavelength of maximum intensity were influenced by the amount of Mn ions present in the precursor. The XRD spectra for ZnO nanoparticles show the entire peaks corresponding to the various planes of wurtzite ZnO, indicating a single phase. The diffraction peaks of doped samples are slightly shifted to lower angles with an increase in the Mn ion concentration, signifying the expansion of the lattice constants and increase in the band gap of ZnO. All the samples show the absorption in the visible region. The absorbance spectra show that the excitonic absorption peak shifts towards the lower wavelength side with the Mn-doped ZnO nanoparticles. The PL spectra of undoped ZnO consist of UV emission at 388 nm and broad visible emission at 560 nm with varying relative peak intensities. The doping of ZnO with Mn quenches significantly the green emission while UV luminescence is slightly affected.
EN
Absorption of calcium is regulated by many endogenous and exogenous factors. Prolactin is important regulator. Numerous studies indicate that prolactin can stimulate calcium transport in the small intestine in vitro and in vivo. This is especially important during the growing demand for calcium in pregnancy and in lactation. There is report the role of prolactin in maintaining calcium homeostasis.
PL
Wchłanianie wapnia regulują liczne czynniki endogenne i egzogenne, m.in. prolaktyna. Jak wynika z wielu badań, może ona stymulować transport wapnia w jelicie cienkim w warunkach in vitro oraz in vivo. Jest to szczególnie ważne w okresie wzrostu zapotrzebowania na wapń w okresie ciąży i laktacji. W licznych doniesieniach wskazano na rolę prolaktyny w zachowaniu homeostazy wapniowej.
EN
Epilepsy is one of the oldest known diseases. The word epilepsia has 2 500 years and comes from the Greek epi­lamvanein, which means ‘attack’, ‘grab’, ‘possess’. Seizures were treated as an expression possessed by demons, evil spirits and therefore for a long time it was considered as “sacred disease”. Epilepsy is not a disease in the clas­sic sense, but rather a complex pathophysiological process, the numerous and complex symptoms are the result of various disorders of brain function. Epilepsy is one of the most difficult problems neuroepidemiology. Seizures are an expression of pathological brain activity in different areas of the course of many disease processes. Source discharges in the clinical pathological form of epileptic seizure can be traumatic scars, compression changes, in­flammatory, degenerative, vascular fire or developmental disorders. Focal epileptic tissue is modified zone lying between the damage and the area healthy. This is a group of neurons that generates periodic paroxysmal bioelectri­cal activity in the form of paroxysmal discharge depolarization generating clinical seizures. Most epilepsies are pri­mary brain disorder, but there are also many processes outbrain disturbing systemic homeostasis. In the treatment of epilepsy, there is no one standard way to proceed. The aim of epilepsy treatment is complete seizure control and getting the least side effects during treatment with antiepileptic drugs. Knowledge and experience are the most im­portant practitioners of the factors contributing to the care of patients with epilepsy. The drug should be tailored to the type of seizure or epilepsy syndrome, the frequency and severity of seizures. The emergence of a new gener­ation of drugs gave them some advantage over older-generation drugs. They are characterized by greater specific­ity of action, improved pharmacokinetic properties, better evaluation of clinical trials and less side effects. These drugs are in clinical trials, and direct observation of lessons can be drawn that they are very useful in some types of epilepsy. There is no doubt that further research and observation
PL
Padaczka jest jedną z najdłużej znanych chorób. Słowo epilepsia liczy 2500 lat i pochodzi od greckiego epilamvanein, co znaczy ‘atakować’, ‘chwycić’, ‘posiąść’. Napady padaczkowe traktowane były jako wyraz owładnięcia przez demony, złe duchy, w związku z czym padaczkę przez długi czas uważano za „świętą chorobę”. Nie jest to choroba w klasycznym znaczeniu, a raczej skomplikowany proces patofizjologiczny, którego bardzo liczne i złożone objawy są wynikiem różnych zaburzeń funkcji mózgu. Padaczka należy do najtrudniejszych problemów neuroepidemiolo­gicznych. Napady padaczkowe są wyrazem patologicznej czynności różnych obszarów mózgu w przebiegu wielu procesów chorobowych. Źródłem patologicznych wyładowań w klinicznej formie napadu padaczkowego mogą być blizny pourazowe, zmiany uciskowe, zapalne, zwyrodnieniowe, ogniska naczyniopochodne czy zaburze­nia rozwojowe. Ogniskiem padaczkowym jest strefa zmienionej tkanki, leżącej między uszkodzeniem a okolicą zdrową. To grupa neuronów generująca okresowo napadową czynność bioelektryczną w formie napadowych wy­ładowań depolaryzacyjnych generujących kliniczny napad padaczkowy. Większość padaczek to zaburzenia pier­wotne mózgowe, choć istnieje również wiele procesów pozamózgowych zaburzających homeostazę ustrojową. W leczeniu padaczki nie występuje jeden standardowy sposób postępowania. Celem terapii jest całkowita kontrola napadów i uzyskanie jak najmniejszych objawów niepożądanych podczas leczenia lekami przeciwpadaczkowymi. Wiedza i doświadczenie lekarzy praktyków są najistotniejszym czynnikiem wpływającym na opiekę nad chorym z padaczką. Lek powinien być dostosowany do typu napadu lub zespołu padaczkowego, częstości i ciężkości na­padów. Pojawienie się leków nowej generacji dało im pewną przewagę w stosunku do starszych leków. Cechują je: większa swoistość działania, lepsze właściwości farmakokinetyczne, lepsza ocena klinicznych prób i słabsze objawy niepożądane. Z badań klinicznych i z bezpośrednich obserwacji wynika, iż są to leki bardzo przydatne w niektó­rych typach padaczek. Nie ulega wątpliwości, że potrzebne są dalsze badania i obserwacje.
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