for plant cell culture was improved. Diameter of the upper part of the bioreactor, was expanded from 155 to 220 mm. Function of a draughtube was changed from a suspension riser to a downcomer. Instead of original aeration tube with holes stainless steel sintered air sparger was introduced. As a result the aeration rate was reduced sixfold for the same kLa value, and the culture foaming and cell deposit on the bioreactor wall was markedly limited.
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