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A short overview of vitamin C and selected cells of the immune system

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Pavlovic V., Sarac M.
Open Medicine
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2011
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vol. 6
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issue 1
1-10
EN
Vitamin C (ascorbic acid) is an essential water-soluble nutrient that primarily exerts its effect on a host defense mechanisms and immune homeostasis and is the most important physiological antioxidant. Stable intake of vitamin C is essential for life in humans because the body does not synthesize it. Even the numerous studies have demonstrated that vitamin C supplementation stimulates the immune system, prevents DNA damage and significantly decreases the risk of a wide range of pathologies; the potential protective mechanisms are still largely unknown. This review summarizes the recently known facts about the role of vitamin C on the selected cells of the immune system and potential molecular mechanisms involved. Further, in this review, many new data about the positive effects of vitamin C on the immune system, potential toxicological effects, vitamin C supplementation in disease development, as well as some proposed mechanisms of vitamin C activity, are discussed.
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Nutritional Composition, Minerals, Vitamin C and Antioxidant Analysis of Yellow Mombin (Spondias mombin L.) Nut

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Odokwo E. O., Uzoekwe N. M.
World News of Natural Sciences
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2024
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vol. 53
86-93
EN
The nutritional, mineral, Vitamin C and antioxidant capacity profiling of the nut of Spondias mombin has been carried out. The nut of S. mombin (NSM) was extracted from its fruit and then profiled quantitatively for its nutritional, mineral and vitamin C contents using the AOAC standard procedures. The antioxidant capacity of the methanol extract of NSM was carried out using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical assay and ferric reducing antioxidant potential (FRAP) techniques. The nut was found to have nutritional facts of: moisture content (12.24±0.06%), lipid content (1.69±0.01%), fibre content (45.27±0.32%), protein content (5.69±0.04%), ash content (0.41±0.02%) and carbohydrate content (34.70±0.33%). The mineral content in mg/g of sample was found to contain: K (7.014), Na (2.966), Ca (1.333), Mg (0.690), Fe (0.131), Cu (0.079), Zn (0.015), Cd (0.004) and Cr (0.009). Pb was not detected. The vitamin C content was 3.89 mg, DPPH antioxidant potential increases as concentration of NSM increases from 25.00 µg/ml to 400 µg/mL and FRAP was observed at 400 μg/ml NSM to be 75.304±0.002 mgAAE. The nut of S. mombin has shown to be good sources for alternative nutrition and as a base for minerals rich in cellular ions. The nut of S. mombin has exhibited antioxidant capacity which can be attributed to the presence of some vital phytoconstituents.
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