Search results

1

Mice can learn roughness discrimination with vibrissae in a jump stand apparatus

100%

Cybulska-Klosowicz A., Kossut M.

|

EN

An adaptation of roughness dicrimination task successfully used on rats was performed on mice. It was found that mice can master discrimination of rough surfaces using only mystacial vibrissae. This task can be used for studying sensory abilities of genetically modified mice as well as dynamics and pharmacology of complex sensory learning.

2

Topography of primary afferent projections in the trigeminal sensory nuclei of rats

88%

Florence S. L., Lakshman S.

Acta Neurobiologiae Experimentalis

|

1995

|

vol. 55

|

issue 3

193-200

EN

The afferent projection pattern from individual vibrissae follicles was related to the distribution of cytochrome oxidase (CO) dark cell clusters in the trigeminal sensory nuclei of adult rats to determine whether segregated primary afferent projections limit the extend of the topogaphic recognizations that can occur at the level of the brainstem on a short term basis after changes in sensory driven activity.The results indicate that the projections to all the brain stem trigeminal subnuclei, including the principal sensory nucleus and the three subdivisions of the spina trigeminal nucleus, are topographic; however, the extend to which label from subdivision to subdivision.In the principal sensory nucleus there is nearly a one to one relationship between the inputs from the vibressae follicles and the corresponding CO-dense clusters.Thus, little overlap in inputs from different vibrissae rows is likely.In contrast, in the parts interpolaris and, to a lasser extend, in the pars caudalis, inputs from individual vibrissae follicles extend beyond the appropriate CO-dark patch into adjacent whisker patches; thus inputs to these subdivisions from different vibrissae likely overlap more extensively.

3

Functional plasticity and neurotransmitter receptor binding in the vibrissal barrel cortex

75%

Kossut M., Glazewski S., Siucinska E., Skangiel-Kramska J.

Acta Neurobiologiae Experimentalis

|

1993

|

vol. 53

|

issue 1

161-173

EN

A form of activity dependent, functional plasticity can be induced in the barrel cortex by sensory deprivation without damage to the sensory receptors. Changes of cortical representation of a spared C3 vibrissa, when all other whiskers were plucked out, were mapped with 2-deoxyglucose autoradiography in mice and rats after a short-lasting deprivation. An increase in the volume of cortical column activated by the spared vibrissa was found previously that if deprivation is commenced immediately after birth, yhe changes in cortical representation of the spared whisker appeared in the third week of life. In search of a possible reason for the delayed expression of functional plasticity in neonatal animals we examined the developmental curves of neurotransmitter receptor binding for several transmitters thought to be involved in plstic processes of the cerebral cortex. We found that the beta noradrenergic and miscarinic cholinergic receptor binding increased rapidly at the end of the second postnatal week and subsequently remained high. By contrast, the metabotropic glutamate receptor binding decreased during the first month of postnatal development. The AMPA receptors binding values rose during the first two weeks of life, and then decreased. Together with our previous data on the development of NMDA and GABA receptor and voltage dependent calcium channel binding, the results suggest that slow development of functional plasticity in neonatal animals may be due to low levels of receptors of several neurotransmitters implicated in brain plasticity.

Refine search results

3 Acta Neurobiologiae Experimentalis

1 2001

1 1995

1 1993

2 Kossut M.

1 Cybulska-Klosowicz A.

1 Florence S. L.

1 Glazewski S.

1 Lakshman S.

1 Siucinska E.

1 Skangiel-Kramska J.

Mice can learn roughness discrimination with vibrissae in a jump stand apparatus

Topography of primary afferent projections in the trigeminal sensory nuclei of rats

Functional plasticity and neurotransmitter receptor binding in the vibrissal barrel cortex