Full-text resources of PSJD and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl
Preferences help
Polish version English version Language
enabled [disable] Abstract
Number of results

Results found: 3

Number of results on page
first rewind previous Page / 1 next fast forward last

Search results

Search:
in the keywords:  UREMIA
help Sort By:

help Limit search:
first rewind previous Page / 1 next fast forward last
1

Uremic autonomic neuropathy - pathogenesis and diagnosis

100%
Rozentryt P., Stryjewski D., Zembala M.
Postępy Higieny i Medycyny Doświadczalnej
|
1995
|
vol. 49
|
issue 5
671-689
EN
Autonomic impairment is associated with poor prognosis in many diseases.The pathogenesis of the uremic autonomic neuropathy has not been convincingly established, so the article reviews available information on factors involved in its development, futhermore the autors put forward their own hypothetical scheme of the pathogenesis.The last section outlines the methods most commonly used for its diagnosis and finally the autors discuss symptoms suggestive of this neuropathy in clinical setting.
2

Increased whole blood chemiluminescence in patients with chronic renal failure independent of hemodialysis treatment

100%
Rysz J., Potargowicz E., Banach M., Luczynska M., Stolarek R., Bialasiewicz P., Kasielski M., Cialkowska-Rysz A., Nowak D.
Archivum Immunologiae et Therapiae Experimentalis
|
2006
|
vol. 54
|
issue 5
347-352
EN
Introduction: The luminol-enhanced whole blood chemiluminescence (LBCL) assay is a rapid assay for the measurement of reactive oxygen species (ROS) generation by circulating phagocytes. This study's aim was to determine if patients on maintenance hemodialysis (HD) and non-dialyzed patients with chronic renal failure (CRF) have altered LBCL and if dialysis itself affects ROS production in the blood. Materials and Methods: Twenty-six HD patients, 11 non-dialyzed patients with CRF, and 20 gender- and age-matched healthy controls were studied. Resting (rCl) and 210?5 M n-formyl-methionyl-leucyl-phenylalanine-stimulated LBCL (peak chemiluminescence: pCl, total light emission after agonist addition: tCl) calculated per 104 phagocytes present in the 3-l blood samples were measured with a Bio-Orbit? 1251 luminometer at 37?C for 11 min. Results: Prior to the HD session, median rCL, pCL, and tCL were 1.5, 3.0, and 2.8 times higher in HD patients than in healthy controls (p<0.01) and tended to increase at the end of the session. Significant increases in tCl were observed at 30 min and 240 min (end) of HD (1023.5 vs. 1810.6 vs. 2006.8 arbitrary unitss/104 phagocytes, n=9, p<0.05). Median pCl and tCl were 5.0 and 4.3 times higher in non-dialyzed patients with CRF than in healthy controls (p<0.001). However, no significant differences were found between pre- and post-HD LBCL of HD patients and the LBCL of non-dialyzed patients with renal failure. Conclusions: Blood from patients with renal failure generates elevated amounts of oxidants independently of HD treatment. This may add to the understanding of the nature of oxidative stress and suggests the need of antioxidant treatment in these patients.
3

The influence of yeast killer toxins on the cytotoxicity of shiga-like toxins Part I ? The effect of killer toxins on mammalian cells

63%
Salek A. T.
Biotechnologia
|
2003
|
issue 1
244-256
EN
It is evident that the results of preliminary experiments with 5 different yeast killer proteins did not show emphatic cytotoxicity or any adverse effect on any mammalian and embryo-cells. Moreover, they are likely to be harmless to animals? and humans? tissue cells. Therefore, they could be used to explain the pre-therapeutic effect on mammalian cells (mostly animals) in the case of infections by strains Escherichia coli, called EHEC. It was found that the yeast killer toxin from Williopsis mrakii can protect mammalian cells such as HeLa and Vero cells against the challenge by Shiga-Like-Toxins (derived from cultures of pathogenic strains of Escherichia coli). The final activities of tested mammalian cells are better when they are pre-treated by the killer protein, i.e. before the challenge with Shiga-Like-Toxins. It appears that this prophylactic effect could be very interesting for veterinary, which has been proved on a big population (about 2000) of healthy and ill (with diarrhoea, i.e. haemorrhagic colitis) pigs (manuscript ? confidential data). We can conclude that the yeast killer strains are probiotic, i.e. could reduce or eliminate fecal shedding of EHEC strains in pigs prior treated with the developed yeast toxins.
first rewind previous Page / 1 next fast forward last
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.