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  1. 1 Biotechnologia

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  1. 1 1996

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  1. 1 Pietrucha T.

  2. 1 Watala C.

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Staphylokinase - a new approach in the treatment of vascular disease

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Pietrucha T., Watala C.
Biotechnologia
|
1996
|
issue 3
43-51
EN
Staphylokinase is a new promising therapeutic agent with an expanding clinical application in the treatment of vascular disease.In the present paper the autors discuss the biochemical and physiological properties of the recombinant protein.The methods and techniques of protein synthesis, isolation and purification, including the genetic engineering approaches are critically summarized.The emphasis is put onto the critical review of the experiments concerning the use of ataphylokinase in thrombotic models in experimental animals.Moreover, we discuss the potential role and advantages of staphylokinase over the other thrombolytic agents in the treatment of cardiovascular disease in humans.
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