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EN
Many commonly used drugs are typically effective in only 40-60% of the patient population, but still substantial number of subjects experience serious adverse reactions and death directly related to drug use. Personalized medicine uses genomic and molecular data to better target the delivery of healthcare by helping to determine individual patient's response to certain therapies.
EN
Current status of innovative drug industry is briefly presented with emphasis on new biopharmaceuticals introduced in the years 1995-2007. Adverse effects and problems of safety and effectiveness of these pharmacotherapeutics are reviewed. A separate part of the manuscript is devoted to the newly introduced methods of molecular diagnostics based on pharmacogenomics and employed in personalized medicine. Theranostic approach consisting in a joint use of drugs and companion diagnostics are characterized.
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