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  1. 1 Molecular Imprinting

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  1. 1 2016

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  1. 1 Dong J.

  2. 1 Liu Y.

  3. 1 Zhai J.

  4. 1 Zhao M.

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Magnetic surface imprinted hydrogel nanoparticles for specific and reversible stabilization of proteins

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Liu Y., Zhai J., Dong J., Zhao M.
Molecular Imprinting
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2014
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vol. 2
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issue 1
EN
In this work, we demonstrate the unique capability of surface imprinted hydrogels over magnetic nanoparticles (Fe3O4@MIP-NPs) for protection of enzyme proteins from denaturation induced by heat, UV irradiation, ultrasonication and addition of urea. Moreover, the Fe3O4@MIP-NPs successfully enabled rapid renaturation of heat-denatured proteins under mild conditions. These interesting properties of MIP nanoparticles offer useful tools for protection and renaturation of proteins in various applications.
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