Full-text resources of PSJD and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl
Preferences help
Polish version English version Language
enabled [disable] Abstract
Number of results

Results found: 2

Number of results on page
first rewind previous Page / 1 next fast forward last

Search results

Search:
in the keywords:  Silymarin
help Sort By:

help Limit search:
first rewind previous Page / 1 next fast forward last
1
Publication available in full text mode
Content available

IN VITRO ANTIVIRAL AND ANTIOXIDANT ACTIVITIES OF SILYMARIN AND PANAX GINSENG ON VERO CELLS INFECTED WITH BOVINE EPHEMERAL FEVER VIRUS AND BLUE TONGUE VIRUS

100%
DiK B., AVCI O., DiK I.
Acta Poloniae Pharmaceutica - Drug Research
|
2019
|
vol. 76
|
issue 2
291-297
EN
The inadequacy of antiviral drugs in the treatment of viral diseases, has led to herbal medicine. It was aimed to determine the antiviral and antioxidant activities of Silymarin and Panax ginseng against Bovine Ephemeral Fever Virus (BEFV) and Bluetongue virus (BTV) in cell culture. Silymarin and Panax ginseng were dissolved at the concentration of 400 µg/ml within distillated water. The cell proliferation test was used to evaluate the cytotoxic activity of the Silymarin and Panax ginseng. They were cytotoxic over 50 μg / ml dose in Vero cells. Hence, antiviral activities of subjects were investigated against BEFV at the 25 and 50 µg/ ml doses. However, they did not show antiviral activity at any dose level against BTV. Effects of Silymarin and Panax ginseng were evaluated on the total antioxidant capacity (TAC) and thiobarbituric acid reactive substances (TBARS), oxidative stress marker, levels in Vero cells infected with BEFV and BTV. Silymarin (25 and 50 µg/ ml) affected TAC levels in Vero cells infected with BEFV, but it did no effect the TBARS levels in Vero cells infected with BEFV and BTV. Panax ginseng decreased TBARS levels in both diseases, although it did not change TAC levels at same doses on Vero cells infected with BEFV and BTV. In conclusion, it is referred that Silymarin and Panax ginseng may have antiviral some viruses and they have antioxidant, cell protective and inhibitory effects of virus replication.
2
Publication available in full text mode
Content available

Nephroprotective role of Potentilla reptans L. aqueous extract on paracetamol - induced kidney nephrotoxicity in male mice

100%
Muthulingam M., Prabhahar C., Senthilmurugan S., Pugazhendy K., Vijayan P., Baranitharan M.
|
|
vol. 39
76-85
EN
Nephroprotective effects (NPE) of simple Potentilla reptans - aqueous leaf extract (Pr-ALE) leaves on Paracetamol induced kidney poisonousness in wistar rats. Adult male wistar rats (weight range (WR): 200-220g) were divided into 6 groups (n=6). Paracetamol (PA) and Silymarin (SY) stayed managed intraperitoneally arranged the 5th day to rats in all groups but the normal control. Furthermore, a significant nephroprotective (NP) of the aqueous leaf extract (ALE) and oral dose of PA and SY. Pr-ALE did not mortality or significant changes in the body weight. Progression of nephrotoxicity (NT) induced by PA in rats was interfered by Pr-ALE managed, and these effects were correspond to those managed with SY. This is the first record on NPE of Pr against PA-induced NT.
first rewind previous Page / 1 next fast forward last
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.