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Recent advances in enzymatic synthesis of oligosaccharides catalyzed by endo-glycosidasas

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Buchowiecka A., Bielecki S.

Biotechnologia

2000

issue 2

174-183

The review is focused on recent advances in the enzymatic synthesis of oligosaccharides catalysed by endo-glycosidases. Four types of applicable donors (oligo- and polysaccharides, oligosyl fluorides, distorted substrates, glycopeptides) have been presented. Additionally enzymatic glycosylation of glycals by endo-acting glycosidses has been discussed.

Factors inducing synthesis of metallothioneins

100%

Florianczyk B.

Postępy Higieny i Medycyny Doświadczalnej

2000

vol. 54

issue 5

687-697

Metallothioneins (MT) are the widespread proteins in animal world. These proteins are characterized by the great invariability of their structure. While isolated from the different organs of different animals they only slightly differ in the aminoacid composition from one another. Studies on the structure and biological functions of MT have identified four major isoforms (MT-I, -II, -III and ?IV) in mammals. Both MT-I and MT-II genes are expressed in various organs and they are inducible by a variety of metals, hormones, cytokines and xenobiotics. MT-III is expressed only in brain and no specific environmental regulatores have been identified. MT-IV is only expressed in differentiating cells of stratified squamous epithelia.

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1 Biotechnologia

1 Postępy Higieny i Medycyny Doświadczalnej

2 2000

1 Bielecki S.

1 Buchowiecka A.

1 Florianczyk B.

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Recent advances in enzymatic synthesis of oligosaccharides catalyzed by endo-glycosidasas

Factors inducing synthesis of metallothioneins